Aliases for KRT74 Gene
External Ids for KRT74 Gene
Previous GeneCards Identifiers for KRT74 Gene
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This protein belongs to a family of keratins that are specifically expressed in the inner root sheath of hair follicles.[provided by RefSeq, Jun 2009]
GeneCards Summary for KRT74 Gene
KRT74 (Keratin 74) is a Protein Coding gene. Diseases associated with KRT74 include Ectodermal Dysplasia 7, Hair/Nail Type and Hypotrichosis 3. Among its related pathways are Developmental Biology and Keratinization. Gene Ontology (GO) annotations related to this gene include structural molecule activity and keratin filament binding. An important paralog of this gene is KRT71.
UniProtKB/Swiss-Prot Summary for KRT74 Gene
Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable).