Aliases for KRT72 Gene
External Ids for KRT72 Gene
Previous GeneCards Identifiers for KRT72 Gene
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2009]
GeneCards Summary for KRT72 Gene
KRT72 (Keratin 72) is a Protein Coding gene. Diseases associated with KRT72 include Palmoplantar Keratoderma, Nonepidermolytic, Focal Or Diffuse and Loose Anagen Hair Syndrome. Among its related pathways are Developmental Biology and Keratinization. Gene Ontology (GO) annotations related to this gene include structural molecule activity. An important paralog of this gene is KRT71.
UniProtKB/Swiss-Prot Summary for KRT72 Gene
Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable).