Aliases for KRT28 Gene
External Ids for KRT28 Gene
Previous HGNC Symbols for KRT28 Gene
Previous GeneCards Identifiers for KRT28 Gene
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]
GeneCards Summary for KRT28 Gene
KRT28 (Keratin 28) is a Protein Coding gene. Diseases associated with KRT28 include Skin Pilomatrix Carcinoma and Loose Anagen Hair Syndrome. Among its related pathways are Relaxin signaling pathway and Developmental Biology. Gene Ontology (GO) annotations related to this gene include structural molecule activity. An important paralog of this gene is KRT27.
UniProtKB/Swiss-Prot Summary for KRT28 Gene
Essential for the proper assembly of types I and II keratin protein complexes and the formation of keratin intermediate filaments in the inner root sheath (irs).