Aliases for KRT27 Gene
External Ids for KRT27 Gene
Previous HGNC Symbols for KRT27 Gene
Previous GeneCards Identifiers for KRT27 Gene
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]
GeneCards Summary for KRT27 Gene
KRT27 (Keratin 27) is a Protein Coding gene. Diseases associated with KRT27 include Type I. Among its related pathways are Keratinization and Circadian entrainment. Gene Ontology (GO) annotations related to this gene include structural molecule activity. An important paralog of this gene is KRT25.
UniProtKB/Swiss-Prot for KRT27 Gene
Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs).