Aliases for KRT12 Gene
External Ids for KRT12 Gene
Previous GeneCards Identifiers for KRT12 Gene
KRT12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Mutations in this gene lead to Meesmann corneal dystrophy. [provided by RefSeq, Jul 2008]
GeneCards Summary for KRT12 Gene
KRT12 (Keratin 12) is a Protein Coding gene. Diseases associated with KRT12 include Corneal Dystrophy, Meesmann, 1 and Corneal Dystrophy. Among its related pathways are Keratinization and Relaxin signaling pathway. Gene Ontology (GO) annotations related to this gene include structural molecule activity. An important paralog of this gene is KRT24.
UniProtKB/Swiss-Prot Summary for KRT12 Gene
May play a unique role in maintaining the normal corneal epithelial function. Together with KRT3, essential for the maintenance of corneal epithelium integrity (By similarity).