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This gene overlaps with the gene for cysteine endopeptidase AUT-like 4 in a head-to-tail orientation. [provided by RefSeq, Jul 2008]
KRI1 (KRI1 Homolog) is a Protein Coding gene. Diseases associated with KRI1 include Cerebral Cavernous Malformations and Cerebrocostomandibular Syndrome.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003723 | RNA binding | HDA | 22658674 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005730 | nucleolus | IBA,IDA | -- |
GO:0030686 | 90S preribosome | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | IBA | 21873635 |
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | |||||||||||||||||||||||||||||||||||||||||
SP2: | |||||||||||||||||||||||||||||||||||||||||
SP3: | |||||||||||||||||||||||||||||||||||||||||
SP4: | |||||||||||||||||||||||||||||||||||||||||
SP5: | |||||||||||||||||||||||||||||||||||||||||
SP6: | |||||||||||||||||||||||||||||||||||||||||
SP7: | - | - | - | ||||||||||||||||||||||||||||||||||||||
SP8: |
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | KRI1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | KRI1 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | KRI1 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | LOC687183 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Kri1 30 17 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | KRI1 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | KRI1 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | KRI1 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | kri1 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | kri1 30 31 |
|
OneToOne | |
Dr.20345 30 |
|
||||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG5645 30 31 |
|
OneToOne | |
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP007295 30 |
|
||
Worm (Caenorhabditis elegans) |
Secernentea | F54C9.9 30 31 |
|
OneToOne | |
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | KRI1 31 33 |
|
OneToOne | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.3549 31 |
|
OneToOne |
SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs11545166 | - | p.Glu179Ala | |||
rs12984043 | - | p.Gly138Arg | |||
rs1982074 | - | p.Leu445Pro | |||
rs3087689 | - | p.Ser703Pro | |||
rs33999611 | - | p.Arg336Trp |
Disorder | Aliases | PubMed IDs |
---|---|---|
cerebral cavernous malformations |
|
|
cerebrocostomandibular syndrome |
|
|
epithelial recurrent erosion dystrophy |
|
|
dental pulp necrosis |
|
|
myasthenic syndrome, congenital, 4c, associated with acetylcholine receptor deficiency |
|
|