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This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. Experimental evidence indicated that the encoded protein functioned in a similar manner to that of the Drosophila rough deal protein. [provided by RefSeq, Jul 2008] See more...
Aliases for KNTC1 Gene
Aliases for KNTC1 Gene
External Ids for KNTC1 Gene
- HGNC: 17255
- Entrez Gene: 9735
- Ensembl: ENSG00000184445
- OMIM: 607363
- UniProtKB: P50748
Previous GeneCards Identifiers for KNTC1 Gene
- GC12M121730
- GC12U900005
- GC12P122820
- GC12P121450
- GC12P121451
- GC12P121536
- GC12P121577
- GC12P123011
- GC12P119972
Summaries for KNTC1 Gene
-
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. Experimental evidence indicated that the encoded protein functioned in a similar manner to that of the Drosophila rough deal protein. [provided by RefSeq, Jul 2008]
GeneCards Summary for KNTC1 Gene
KNTC1 (Kinetochore Associated 1) is a Protein Coding gene. Diseases associated with KNTC1 include Orbital Plasma Cell Granuloma and Chronic Orbital Inflammation. Among its related pathways are Signaling by GPCR and Mitotic Prometaphase.
UniProtKB/Swiss-Prot Summary for KNTC1 Gene
-
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores (PubMed:11146660, PubMed:11590237, PubMed:15824131). Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
Additional gene information for KNTC1 Gene
- HGNC(17255)
- Entrez Gene(9735)
- Ensembl(ENSG00000184445)
- OMIM(607363)
- UniProtKB(P50748)
- Open Targets Platform(ENSG00000184445)
- Search for KNTC1 at DataMed
- Search for KNTC1 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for KNTC1 Gene
Genomics for KNTC1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for KNTC1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around KNTC1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for KNTC1
- Top Transcription factor binding sites by QIAGEN in the KNTC1 gene promoter:
-
- c-Myc
- E4BP4
- Elk-1
- HEN1
- Lmo2
- Max1
- NF-kappaB1
- Pax-4a
- PPAR-gamma2
Genomic Locations for KNTC1 Gene
Genomic Locations for KNTC1 Gene
- chr12:122,527,106-122,626,409
- (GRCh38/hg38)
- Size:
- 99,304 bases
- Orientation:
- Plus strand
- chr12:123,011,793-123,110,947
- (GRCh37/hg19)
- Size:
- 99,155 bases
- Orientation:
- Plus strand
Genomic View for KNTC1 Gene
Genes around KNTC1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q24.31 by HGNC
- 12q24.31 by Entrez Gene
- 12q24.31 by Ensembl
KNTC1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for KNTC1 Gene
Proteins for KNTC1 Gene
-
Protein details for KNTC1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P50748-KNTC1_HUMAN
- Recommended name:
- Kinetochore-associated protein 1
- Protein Accession:
- P50748
- A7E2C4
- B3KSG2
Protein attributes for KNTC1 Gene
- Size:
- 2209 amino acids
- Molecular mass:
- 250749 Da
- Quaternary structure:
-
- Interacts with ZW10; the interaction is required for stable association with the kinetochore. Component of the RZZ complex composed of KNTC1/ROD, ZW10 and ZWILCH; in the complex interacts directly with ZWILCH.
- SequenceCaution:
-
- Sequence=BAA11483.2; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for KNTC1 Gene
Post-translational modifications for KNTC1 Gene
Other Protein References for KNTC1 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for KNTC1
- Novus Biologicals Antibodies for KNTC1
-
Abcam antibodies for KNTC1
- Invitrogen Antibodies for KNTC1 (AFLGC-KNTC1)
-
Biorbyt antibodies for KNTC1
-
Santa Cruz Biotechnology (SCBT) Antibodies for KNTC1
Protein Products
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Abcam proteins for KNTC1
Assay Products
- antibodies-online: Show 3 available KNTC1 Elisa Kits ranked by validation data
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-
Quality Products:
-
Signalway ELISA kits for KNTC1
No data available for DME Specific Peptides for KNTC1 Gene
Domains & Families for KNTC1 Gene
Gene Families for KNTC1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for KNTC1 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for KNTC1 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ36151 fis, clone TESTI2025365, highly similar to Kinetochore-associated protein 1 (B3KSG2_HUMAN)
- Rough deal homolog (KNTC1_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for KNTC1 Gene
Function for KNTC1 Gene
Molecular function for KNTC1 Gene
- UniProtKB/Swiss-Prot Function:
- Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores (PubMed:11146660, PubMed:11590237, PubMed:15824131). Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
Phenotypes From GWAS Catalog for KNTC1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 11146660 |
Phenotypes for KNTC1 Gene
- MGI mutant phenotypes for KNTC1:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for KNTC1:
Animal Models for KNTC1 Gene
- MGI Knock Outs for KNTC1:
-
- Kntc1 Kntc1<tm1b(EUCOMM)Hmgu>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for KNTC1 - Select products 50% OFF >
- * KNTC1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
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-
Santa Cruz Biotechnology (SCBT) CRISPR for KNTC1
miRNA for KNTC1 Gene
- miRTarBase miRNAs that target KNTC1
-
- hsa-miR-193b-3p (MIRT016317)
- hsa-miR-484 (MIRT041835)
- hsa-miR-149-5p (MIRT045471)
- hsa-miR-183-5p (MIRT047167)
- hsa-miR-5584-3p (MIRT656786)
- hsa-miR-6875-3p (MIRT656787)
- hsa-miR-5006-3p (MIRT656788)
- hsa-miR-4755-5p (MIRT656789)
- hsa-miR-632 (MIRT656790)
- hsa-miR-4288 (MIRT656791)
- hsa-miR-527 (MIRT656792)
- hsa-miR-518a-5p (MIRT656793)
- hsa-miR-211-5p (MIRT656794)
- hsa-miR-204-5p (MIRT656795)
- hsa-miR-623 (MIRT656796)
- hsa-miR-6886-3p (MIRT656797)
- hsa-miR-4778-3p (MIRT656798)
- hsa-miR-6832-3p (MIRT656799)
- hsa-miR-5088-3p (MIRT656800)
- hsa-miR-129-2-3p (MIRT656801)
- hsa-miR-129-1-3p (MIRT656802)
- hsa-miR-3145-5p (MIRT764998)
- hsa-miR-4771 (MIRT772197)
- hsa-miR-519d-5p (MIRT773730)
- hsa-miR-5583-3p (MIRT774725)
- hsa-miR-633 (MIRT776136)
- hsa-miR-885-5p (MIRT782546)
miRNA Products
Inhibitory RNA Products
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Clone Products
- Applied Biological Materials (abm): Clones for KNTC1 - Select products 50% OFF >
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- Sino Biological Human cDNA Clone for KNTC1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for KNTC1
Cell Line Products
-
Horizon Cell Lines for KNTC1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for KNTC1 Gene
Localization for KNTC1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for KNTC1 Gene
- Cytoplasm. Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Note=Dynamic pattern of localization during the cell cycle. At interphase, uniformly distributed throughout the cytoplasm and nucleus. By prophase and until late stages of prometaphase, a fraction of the total pool is concentrated at kinetochores. By metaphase, detected at kinetochores, along spindle fibers and most prominently at the poles. By late anaphase until the end of telophase, no longer detectable on kinetochores or along spindle fibers, but still present at the spindle poles.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| cytoskeleton | 5 |
| nucleus | 5 |
| cytosol | 4 |
| extracellular | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
- Cytosol (3)
- Plasma membrane (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000775 | chromosome, centromeric region | IEA | -- |
| GO:0000776 | kinetochore | IEA | -- |
| GO:0000777 | condensed chromosome kinetochore | IEA | -- |
| GO:0000922 | spindle pole | IDA | 11146660 |
| GO:0005634 | nucleus | NAS | 11146660 |
Pathways & Interactions for KNTC1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cell Cycle, Mitotic |
.83
|
.60
|
| 2 | Mitotic Metaphase and Anaphase |
.94
|
|
| 3 | Mitotic Prometaphase | ||
| 4 | Signaling by Rho GTPases | ||
| 5 | Signaling by GPCR | ||
Pathways by source for KNTC1 Gene
12 Reactome pathways for KNTC1 Gene
Interacting Proteins for KNTC1 Gene
Selected Interacting proteins:
P50748-KNTC1_HUMAN
ENSP00000328236
for KNTC1 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for KNTC1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007049 | cell cycle | IEA | -- |
| GO:0007093 | mitotic cell cycle checkpoint | IDA | 11146660 |
| GO:0007096 | regulation of exit from mitosis | NAS | 11146660 |
| GO:0051301 | cell division | IEA | -- |
| GO:0065003 | protein-containing complex assembly | NAS | 11146660 |
No data available for SIGNOR curated interactions for KNTC1 Gene
Transcripts for KNTC1 Gene
mRNA/cDNA for KNTC1 Gene
- 1 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 15 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000333479 6974 nts (view in UCSC)
- ENST00000377192 1519 nts (view in UCSC)
- ENST00000423927 1250 nts (view in UCSC)
- ENST00000436959 2412 nts (view in UCSC)
- ENST00000450485 3655 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for KNTC1 - Select products 50% OFF >
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- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for KNTC1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for KNTC1
-
Santa Cruz Biotechnology (SCBT) CRISPR for KNTC1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for KNTC1
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Clone Products
- Applied Biological Materials (abm): Clones for KNTC1 - Select products 50% OFF >
- * KNTC1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for KNTC1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for KNTC1
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | · | 10c | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19a | · | 19b | · | 19c | ^ | 20 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - |
| ExUns: | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25a | · | 25b | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||
| SP2: | |||||||||||||||||||
| SP3: | |||||||||||||||||||
| SP4: | - | ||||||||||||||||||
| SP5: | |||||||||||||||||||
| SP6: | - | ||||||||||||||||||
| SP7: | |||||||||||||||||||
| SP8: |
Relevant External Links for KNTC1 Gene
- GeneLoc Exon Structure for
- KNTC1
Expression for KNTC1 Gene
mRNA differential expression in normal tissues according to GTEx for KNTC1 Gene
This gene is overexpressed in Testis (x4.1).
This gene is overexpressed in Tlymphocyte (19.1), Blymphocyte (14.3), Neutrophil (11.3), and Breast (8.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for KNTC1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for KNTC1
SOURCE GeneReport for Unigene cluster for KNTC1 Gene:
Hs.300559mRNA Expression by UniProt/SwissProt for KNTC1 Gene:
P50748-KNTC1_HUMAN
Tissue specificity:
High expression in testis.
Evidence on tissue expression from TISSUES for KNTC1 Gene
- Bone marrow(4.5)
- Blood(2.7)
- Skin(2.5)
- Kidney(2.3)
- Nervous system(2.1)
- Thyroid gland(2.1)
- Intestine(2.1)
- Lymph node(2)
Primer Products
-
OriGene qPCR primer pairs for KNTC1
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for KNTC1 Gene
Orthologs for KNTC1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | KNTC1 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | KNTC1 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | KNTC1 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Kntc1 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Kntc1 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | KNTC1 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | KNTC1 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | KNTC1 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | KNTC1 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | kntc1 30 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.9622 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | kntc1 30 31 |
|
OneToOne | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | rod 31 |
|
OneToOne | |
| Worm (Caenorhabditis elegans) |
Secernentea | rod-1 31 |
|
OneToOne |
- Species where no ortholog for KNTC1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for KNTC1 Gene
- ENSEMBL:
- Gene Tree for KNTC1 (if available)
- TreeFam:
- Gene Tree for KNTC1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for KNTC1: view image
Paralogs for KNTC1 Gene
Pseudogenes.org Pseudogenes for KNTC1 Gene
No data available for Paralogs for KNTC1 Gene
Variants for KNTC1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for KNTC1 Gene
| SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs772156434 | Uncertain Significance: Malignant tumor of prostate | 122,626,224(+) | C/T | MISSENSE_VARIANT | |
| rs11837038 | - | p.Val2021Gly | |||
| rs17883249 | - | p.Glu738Asp | |||
| rs35315099 | - | p.Thr1506Met | |||
| rs7310898 | - | p.Pro1830Leu |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2658251 | CNV | deletion | 23128226 |
| esv2661880 | CNV | deletion | 23128226 |
| esv2761772 | CNV | gain | 21179565 |
| esv3630978 | CNV | loss | 21293372 |
| nsv1041677 | CNV | gain | 25217958 |
| nsv1054458 | CNV | loss | 25217958 |
| nsv826529 | CNV | gain | 20364138 |
| nsv826530 | CNV | loss | 20364138 |
| nsv957298 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
86.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
8.97;
87.33% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for KNTC1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- KNTC1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KNTC1 Gene
Disorders for KNTC1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| orbital plasma cell granuloma |
|
|
| chronic orbital inflammation |
|
|
| orbital disease |
|
|
| mikulicz disease |
|
|
| dacryoadenitis |
|
|
Search KNTC1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for KNTC1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for KNTC1 Gene
Publications for KNTC1 Gene
- Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery. (PMID: 20462495) Civril F … Musacchio A (Structure (London, England : 1993) 2010) 3 4 23
- Zwilch, a new component of the ZW10/ROD complex required for kinetochore functions. (PMID: 12686595) Williams BC … Goldberg ML (Molecular biology of the cell 2003) 3 4 23
- The ZW10 and Rough Deal checkpoint proteins function together in a large, evolutionarily conserved complex targeted to the kinetochore. (PMID: 11590237) Scaërou F … Goldberg ML (Journal of cell science 2001) 2 3 4
- Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores. (PMID: 11146660) Chan GK … Yen TJ (Nature cell biology 2000) 2 3 4
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
ExternalLinks
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- Invitrogen Antibodies for KNTC1 (AFLGC-KNTC1)
- VectorBuilder Custom and pre-made DNA vectors for KNTC1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for KNTC1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for KNTC1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for KNTC1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for KNTC1
- antibodies-online: Show 5 available KNTC1 Antibodies ranked by validation data
- Compare Top KNTC1 Antibodies
- antibodies-online: Show 3 available KNTC1 Elisa Kits ranked by validation data
- Compare Top KNTC1 Elisa Kits
- Quality Products:
- antibodies-online: Search results for available KNTC1 related products ranked by validation data
- Santa Cruz Biotechnology (SCBT) Antibodies for KNTC1
- Search Santa Cruz Biotechnology (SCBT) for KNTC1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for KNTC1
- Horizon Cell Lines for KNTC1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for KNTC1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for KNTC1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for KNTC1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KNTC1
- Biorbyt antibodies for KNTC1
- Signalway ELISA kits for KNTC1
Sources for KNTC1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB