Aliases for KMT2B Gene
Aliases for KMT2B Gene
- Lysine Methyltransferase 2B 2 3 5
- Myeloid/Lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila) 4 2 3
- Myeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 4 3 4
- Lysine (K)-Specific Methyltransferase 2B 2 3
- Histone-Lysine N-Methyltransferase 2B 2 3
- WBP-7 3 4
- HRX2 3 4
- MLL2 3 4
- MLL4 3 4
- TRX2 3 4
- WBP7 3 4
- Histone-Lysine N-Methyltransferase MLL4 3
External Ids for KMT2B Gene
- HGNC: 15840
- Entrez Gene: 9757
- Ensembl: ENSG00000272333
- OMIM: 606834
- UniProtKB: Q9UMN6
Previous GeneCards Identifiers for KMT2B Gene
- GC19P036214
- GC19P036217
- GC19P035801
- GC19P035830
- GC19P035847
- GC19P036006
- GC19P036169
- GC19P036242
- GC19P036411
- GC19P036572
Summaries for KMT2B Gene
-
This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008]
GeneCards Summary for KMT2B Gene
KMT2B (Lysine Methyltransferase 2B) is a Protein Coding gene. Diseases associated with KMT2B include Dystonia 28, Childhood-Onset and Spindle Cell Sarcoma. Among its related pathways are Chromatin organization and PKMTs methylate histone lysines. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and histone methyltransferase activity (H3-K4 specific). An important paralog of this gene is KMT2A.
UniProtKB/Swiss-Prot for KMT2B Gene
-
Histone methyltransferase. Methylates Lys-4 of histone H3. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation.
Additional gene information for KMT2B Gene
- Monarch Initiative
- Search for KMT2B at DataMed
- Search for KMT2B at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KMT2B Gene
Genomics for KMT2B Gene
GeneHancer (GH) Regulatory Elements for KMT2B Gene
Promoters and enhancers for KMT2B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around KMT2B on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for KMT2B Gene
Genomic Locations for KMT2B Gene
- chr19:35,717,995-35,738,880
- (GRCh38/hg38)
- Size:
- 20,886 bases
- Orientation:
- Plus strand
- chr19:36,208,921-36,229,779
- (GRCh37/hg19)
- Size:
- 20,859 bases
- Orientation:
- Plus strand
Genomic View for KMT2B Gene
Genes around KMT2B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.12 by Entrez Gene
- 19q13.12 by HGNC
- 19q13.12 by Ensembl
KMT2B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for KMT2B Gene
Proteins for KMT2B Gene
-
Protein details for KMT2B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UMN6-KMT2B_HUMAN
- Recommended name:
- Histone-lysine N-methyltransferase 2B
- Protein Accession:
- Q9UMN6
- O15022
- O95836
- Q96GP2
- Q96IP3
- Q9UK25
- Q9Y668
- Q9Y669
Protein attributes for KMT2B Gene
- Size:
- 2715 amino acids
- Molecular mass:
- 293515 Da
- Quaternary structure:
-
- Component of the menin-associated histone methyltransferase complex, at least composed of KMT2B/MLL4, ASH2L, RBBP5, WDR5, DPY30, MEN1; the complex interacts with POLR2A and POLR2B via MEN1. Interacts with NFE2. Interacts with KDM6B.
Protein Expression for KMT2B Gene
Post-translational modifications for KMT2B Gene
Other Protein References for KMT2B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
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-
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- Invitrogen Antibodies for KMT2B (AFLGC-KMT2B)
- antibodies-online: Search results for 25 available KMT2B Antibodies ranked by validation data
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- ABIN2611792
- ABIN2887614
- ABIN4329263
- ABIN462281
- ABIN268620
- ABIN4329262
- ABIN203215
- ABIN203655
- ABIN2624632
- ABIN2624631
- ABIN2611792
- ABIN2887614
- ABIN4329263
- ABIN462281
- ABIN268620
- ABIN4329262
- ABIN203215
- ABIN203655
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- ABIN4329263
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- GeneTex KMT2B Antibody for KMT2B
-
Boster Bio Antibodies for KMT2B
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Santa Cruz Biotechnology (SCBT) Antibodies for KMT2B
Protein Products
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- Search GeneTex for Proteins for KMT2B
Assay Products
No data available for DME Specific Peptides for KMT2B Gene
Domains & Families for KMT2B Gene
Gene Families for KMT2B Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Enzymes
- Predicted intracellular proteins
- Transcription factors
Protein Domains for KMT2B Gene
Suggested Antigen Peptide Sequences for KMT2B Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9UMN6UniProtKB/Swiss-Prot:
KMT2B_HUMAN :- Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
- Family:
-
- Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
Function for KMT2B Gene
Molecular function for KMT2B Gene
- UniProtKB/Swiss-Prot Function:
- Histone methyltransferase. Methylates Lys-4 of histone H3. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development. Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation.
- UniProtKB/Swiss-Prot CatalyticActivity:
- S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
Enzyme Numbers (IUBMB) for KMT2B Gene
Phenotypes From GWAS Catalog for KMT2B Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | ISA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003700 | DNA binding transcription factor activity | NAS | 10409430 |
| GO:0005515 | protein binding | IPI | 17021013 |
| GO:0008168 | methyltransferase activity | IEA | -- |
Phenotypes for KMT2B Gene
- MGI mutant phenotypes for KMT2B:
-
inferred from 7 alleles
- cardiovascular system phenotype
- homeostasis/metabolism phenotype
- nervous system phenotype
- endocrine/exocrine gland phenotype
- mortality/aging
- cellular phenotype
- liver/biliary system phenotype
- reproductive system phenotype
- embryo phenotype
- normal phenotype
- adipose tissue phenotype
- growth/size/body region phenotype
- GenomeRNAi human phenotypes for KMT2B:
Animal Model Products
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-
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-
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miRNA for KMT2B Gene
- miRTarBase miRNAs that target KMT2B
-
- hsa-mir-7515 (MIRT536433)
- hsa-mir-302a-5p (MIRT536434)
- hsa-mir-3154 (MIRT536435)
- hsa-mir-6782-3p (MIRT536436)
- hsa-mir-519c-3p (MIRT536437)
- hsa-mir-519b-3p (MIRT536438)
- hsa-mir-519a-3p (MIRT536439)
- hsa-mir-5692a (MIRT536440)
- hsa-mir-548t-5p (MIRT536441)
- hsa-mir-548az-5p (MIRT536442)
- hsa-mir-526b-3p (MIRT536443)
- hsa-mir-519d-3p (MIRT536444)
- hsa-mir-93-5p (MIRT536445)
- hsa-mir-20a-5p (MIRT536446)
- hsa-mir-17-5p (MIRT536447)
- hsa-mir-106b-5p (MIRT536448)
- hsa-mir-106a-5p (MIRT536449)
- hsa-mir-20b-5p (MIRT536450)
- hsa-mir-153-3p (MIRT536451)
- hsa-mir-1224-3p (MIRT556671)
- hsa-mir-1294 (MIRT737173)
- hsa-mir-1914-3p (MIRT738506)
- hsa-mir-214-3p (MIRT738995)
- hsa-mir-31-5p (MIRT740494)
- hsa-mir-3184-5p (MIRT740860)
- hsa-mir-3619-5p (MIRT741718)
- hsa-mir-3689d (MIRT742469)
- hsa-mir-423-5p (MIRT743258)
- hsa-mir-4316 (MIRT743996)
- hsa-mir-4426 (MIRT744290)
- hsa-mir-4440 (MIRT744512)
- hsa-mir-4459 (MIRT744810)
- hsa-mir-4647 (MIRT746449)
- hsa-mir-4662b (MIRT746703)
- hsa-mir-4688 (MIRT747009)
- hsa-mir-4722-5p (MIRT747603)
- hsa-mir-5194 (MIRT749970)
- hsa-mir-6085 (MIRT751799)
- hsa-mir-6165 (MIRT752510)
- hsa-mir-6734-5p (MIRT754140)
- hsa-mir-6738-5p (MIRT754265)
- hsa-mir-6743-5p (MIRT754409)
- hsa-mir-6789-5p (MIRT756017)
- hsa-mir-6813-5p (MIRT756735)
- hsa-mir-6851-5p (MIRT757592)
- hsa-mir-761 (MIRT759469)
- hsa-mir-7704 (MIRT759730)
- hsa-mir-885-3p (MIRT760386)
miRNA Products
Inhibitory RNA Products
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Clone Products
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OriGene ORF clones in human for KMT2B
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No data available for Transcription Factor Targets and HOMER Transcription for KMT2B Gene
Localization for KMT2B Gene
Subcellular locations from UniProtKB/Swiss-Prot for KMT2B Gene
- Nucleus.
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA | 17500065 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0035097 | histone methyltransferase complex | IDA | 17500065 |
No data available for Subcellular locations from COMPARTMENTS for KMT2B Gene
Pathways & Interactions for KMT2B Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Chromatin organization | ||
| 2 | PKMTs methylate histone lysines | ||
| 3 | Lysine degradation | ||
| 4 | Chromatin Regulation / Acetylation | ||
Pathways by source for KMT2B Gene
1 GeneTex pathway for KMT2B Gene
1 BioSystems pathway for KMT2B Gene
3 Reactome pathways for KMT2B Gene
1 KEGG pathway for KMT2B Gene
1 Cell Signaling Technology pathway for KMT2B Gene
Interacting Proteins for KMT2B Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001541 | ovarian follicle development | IEA | -- |
| GO:0006325 | chromatin organization | IEA | -- |
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006357 | regulation of transcription by RNA polymerase II | IEA | -- |
No data available for SIGNOR curated interactions for KMT2B Gene
Drugs & Compounds for KMT2B Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| s-adenosylmethionine |
|
485-80-3 |
|
Drug Products
Transcripts for KMT2B Gene
mRNA/cDNA for KMT2B Gene
- (6) REFSEQ mRNAs :
- (436) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000420124 8469 bps (uc021usv.1)
- ENST00000606995 195 bps (uc060xgx.1)
- ENST00000592092 823 bps (uc060xgy.1)
- ENST00000585476 2864 bps (uc060xgz.1)
- ENST00000586308 705 bps (uc060xha.1)
CRISPR Products
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-
Santa Cruz Biotechnology (SCBT) CRISPR for KMT2B
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miRNA Products
Inhibitory RNA Products
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Clone Products
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OriGene ORF clones in human for KMT2B
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Expression for KMT2B Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Bone (Muscoskeletal System)
This gene is overexpressed in Pancreatic juice (17.3), Peripheral blood mononuclear cells (12.3), Monocytes (8.8), and Testis (6.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for KMT2B Gene
NURSA nuclear receptor signaling pathways regulating expression of KMT2B Gene:
KMT2BmRNA Expression by UniProt/SwissProt for KMT2B Gene:
Q9UMN6-KMT2B_HUMAN
Tissue specificity:
Widely expressed. Highest levels in testis. Also found in brain with higher expression in the cerebellum than in any other region, bone marrow, heart, muscle, kidney, placenta, spleen, thymus, prostate, ovary, intestine, colon, peripheral blood lymphocytes and pancreas. Often amplified in pancreatic carcinomas.
Primer Products
-
OriGene qPCR primer pairs for KMT2B
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Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for KMT2B Gene
Orthologs for KMT2B Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | -- 34 |
|
OneToOne | |
| LOC455959 33 |
|
||||
| cow (Bos Taurus) |
Mammalia | -- 34 |
|
OneToOne | |
| KMT2B 33 |
|
||||
| dog (Canis familiaris) |
Mammalia | -- 34 |
|
OneToOne | |
| MLL4 33 |
|
||||
| rat (Rattus norvegicus) |
Mammalia | LOC102550344 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Kmt2b 16 34 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | Str.7192 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | kmt2ba 34 |
|
OneToMany | |
| kmt2bb 34 |
|
OneToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | trx 34 |
|
OneToMany | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SET1 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for KMT2B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for KMT2B Gene
- ENSEMBL:
- Gene Tree for KMT2B (if available)
- TreeFam:
- Gene Tree for KMT2B (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for KMT2B: view image
Paralogs for KMT2B Gene
Variants for KMT2B Gene
| SNP ID | Clin | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1057519278 | pathogenic, Dystonia 28, childhood-onset | 35,732,955(+) | C/ | coding_sequence_variant, frameshift, genic_downstream_transcript_variant | |
| rs1057519279 | pathogenic, Dystonia 28, childhood-onset | 35,720,980(+) | C/T | coding_sequence_variant, genic_upstream_transcript_variant, non_coding_transcript_variant, stop_gained | |
| rs1057519280 | pathogenic, Dystonia 28, childhood-onset | 35,733,761(+) | A/G | genic_downstream_transcript_variant, splice_acceptor_variant | |
| rs1057519281 | pathogenic, Dystonia 28, childhood-onset | 35,721,775(+) | C/T | coding_sequence_variant, genic_upstream_transcript_variant, non_coding_transcript_variant, stop_gained, upstream_transcript_variant | |
| rs1057519282 | pathogenic, Dystonia 28, childhood-onset | 35,719,503(+) | CCCCC/CCCCCC | 5_prime_UTR_variant, coding_sequence_variant, frameshift, genic_upstream_transcript_variant, intron_variant, non_coding_transcript_variant |
Residual Variation Intolerance Score:
1.39% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.48;
82.13% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for KMT2B Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KMT2B Gene
Disorders for KMT2B Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| dystonia 28, childhood-onset |
|
|
| spindle cell sarcoma |
|
|
| kabuki syndrome 1 |
|
|
| corneal staphyloma |
|
|
| early-onset generalized dystonia |
|
|
Search KMT2B in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
KMT2B_HUMAN- Dystonia 28, childhood-onset (DYT28) [MIM:617284]: A form of dystonia, a disorder defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYT28 is an autosomal dominant, progressive form characterized by onset in the first decade of life and variable severity. Dystonia begins focally in the lower limbs, resulting in gait difficulties, with later progression to other body regions, including the upper limbs, neck, and orofacial region. {ECO:0000269 PubMed:27839873, ECO:0000269 PubMed:27992417}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for KMT2B
No data available for Genatlas for KMT2B Gene
Publications for KMT2B Gene
- MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell lines. (PMID: 10637508) Huntsman DG … Caldas C (Oncogene 1999) 2 3 4 22 58
- MLL2: A new mammalian member of the trx/MLL family of genes. (PMID: 10409430) FitzGerald KT … Diaz MO (Genomics 1999) 2 3 4 58
- Mutations in the histone methyltransferase gene KMT2B cause complex early-onset dystonia. (PMID: 27992417) Meyer E … Kurian MA (Nature genetics 2017) 3 4 58
- Haploinsufficiency of KMT2B, Encoding the Lysine-Specific Histone Methyltransferase 2B, Results in Early-Onset Generalized Dystonia. (PMID: 27839873) Zech M … Winkelmann J (American journal of human genetics 2016) 3 4 58
- The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4 58
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For KMT2B
- GenScript: Next-day shipping of latest version cDNA ORF clones for KMT2B in any vector
- GenScript Custom Purified and Recombinant Proteins Services for KMT2B
- GenScript Custom Assay Services for KMT2B
- GenScript Custom overexpressing Cell Line Services for KMT2B
- GenScript: Design CRISPR guide RNA sequences for KMT2B
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for KMT2B
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for KMT2B
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for KMT2B
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for KMT2B (AFLGC-KMT2B)
- Cyagen custom Knockout/knockin (KOKI) mouse models for KMT2B
- Addgene plasmids for KMT2B
- antibodies-online: Search results for 25 available KMT2B Antibodies ranked by validation data
- Compare Top KMT2B Antibodies
- Quality Products:
- ABIN4329263
- ABIN462281
- ABIN268620
- ABIN4329262
- ABIN203215
- ABIN203655
- ABIN2624632
- ABIN2624631
- ABIN2611792
- ABIN2887614
- ABIN4329263
- ABIN462281
- ABIN268620
- ABIN4329262
- ABIN203215
- ABIN203655
- ABIN2624632
- ABIN2624631
- ABIN2611792
- ABIN2887614
- ABIN4329263
- ABIN462281
- ABIN268620
- ABIN4329262
- ABIN203215
- ABIN203655
- ABIN2624632
- ABIN2624631
- ABIN2611792
- ABIN2887614
- ABIN4329263
- ABIN462281
- ABIN268620
- ABIN4329262
- ABIN203215
- ABIN203655
- ABIN2624632
- ABIN2624631
- ABIN2611792
- ABIN2887614
- antibodies-online: Search results for 2 available KMT2B Elisa Kits ranked by validation data
- Compare Top KMT2B Elisa Kits
- antibodies-online: Search results for 25 available KMT2B Proteins ranked by validation data
- Compare Top KMT2B Proteins
- GeneTex KMT2B Antibody for KMT2B
- Search GeneTex for Proteins for KMT2B
- Santa Cruz Biotechnology (SCBT) Antibodies for KMT2B
- Search Santa Cruz Biotechnology (SCBT) for KMT2B siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for KMT2B
- Horizon Cell Lines for KMT2B
- genomics-online: cdna clones - Search results for available KMT2B gene related products
- orf clones - Search results for available KMT2B gene related products
- genomics-online: gRNA clones - Search results for available KMT2B gene related products
- genomics-online: primer clones - Search results for available KMT2B gene related products
- genomics-online: shRNA clones - Search results for available KMT2B gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for KMT2B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for KMT2B
- GeneCopoeia miRNA 3'UTR Target clone products for KMT2B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KMT2B
- Boster Bio Antibodies for KMT2B
- Browse Boster Bio ELISA Kits
Sources for KMT2B Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt