Aliases for KLRF1 Gene
External Ids for KLRF1 Gene
Previous GeneCards Identifiers for KLRF1 Gene
KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009]
GeneCards Summary for KLRF1 Gene
KLRF1 (Killer Cell Lectin Like Receptor F1) is a Protein Coding gene. Among its related pathways are Hematopoietic Stem Cells and Lineage-specific Markers and Innate Immune System. Gene Ontology (GO) annotations related to this gene include transmembrane signaling receptor activity and MHC class I receptor activity. An important paralog of this gene is KLRF2.
UniProtKB/Swiss-Prot Summary for KLRF1 Gene
Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.