Aliases for KLK15 Gene
Aliases for KLK15 Gene
External Ids for KLK15 Gene
- HGNC: 20453
- Entrez Gene: 55554
- Ensembl: ENSG00000174562
- OMIM: 610601
- UniProtKB: Q9H2R5
Previous GeneCards Identifiers for KLK15 Gene
- GC19M051957
- GC19M051689
- GC19M056004
- GC19M056020
- GC19M051328
- GC19M047663
Summaries for KLK15 Gene
-
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
GeneCards Summary for KLK15 Gene
KLK15 (Kallikrein Related Peptidase 15) is a Protein Coding gene. Diseases associated with KLK15 include Prostate Cancer. Among its related pathways are MSP-RON Signaling and Collagen chain trimerization. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase activity and serine-type peptidase activity. An important paralog of this gene is KLK11.
UniProtKB/Swiss-Prot for KLK15 Gene
-
Protease whose physiological substrate is not yet known.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KLK15 Gene
Genomics for KLK15 Gene
GeneHancer (GH) Regulatory Elements for KLK15 Gene
Promoters and enhancers for KLK15 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around KLK15 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the KLK15 gene promoter:
Regulatory Element Products
Genomic Locations for KLK15 Gene
Genomic Locations for KLK15 Gene
- chr19:50,825,289-50,837,213
- (GRCh38/hg38)
- Size:
- 11,925 bases
- Orientation:
- Minus strand
- chr19:51,328,545-51,340,469
- (GRCh37/hg19)
Genomic View for KLK15 Gene
Genes around KLK15 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by Ensembl
- 19q13.33 by Entrez Gene
- 19q13.33 by HGNC
KLK15 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for KLK15 Gene
Proteins for KLK15 Gene
-
Protein details for KLK15 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9H2R5-KLK15_HUMAN
- Recommended name:
- Kallikrein-15
- Protein Accession:
- Q9H2R5
- A0AUY8
- Q15358
- Q6ISI0
- Q9H2R3
- Q9H2R4
- Q9H2R6
- Q9HBG9
Protein attributes for KLK15 Gene
- Size:
- 256 amino acids
- Molecular mass:
- 28087 Da
- Quaternary structure:
- No Data Available
Protein Expression for KLK15 Gene
Selected DME Specific Peptides for KLK15 Gene
- Q9H2R5:
-
- LQGIVSWG
- GDSGGPL
- WVLSAAHC
- SQPWQVA
- SGGPLVC
- PGVYTKV
- VRLGEHN
- QGIVSWG
Post-translational modifications for KLK15 Gene
Other Protein References for KLK15 Gene
Antibody Products
- R&D Systems Antibodies for KLK15 (Kallikrein 15)
-
Custom Antibody ServicesOriGene Antibodies for KLK15
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-
Santa Cruz Biotechnology (SCBT) Antibodies for KLK15
Protein Products
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-
Abcam proteins for KLK15
Assay Products
Domains & Families for KLK15 Gene
Gene Families for KLK15 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Enzymes
- Predicted intracellular proteins
- Predicted secreted proteins
Protein Domains for KLK15 Gene
Suggested Antigen Peptide Sequences for KLK15 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9H2R5- Family:
-
- Belongs to the peptidase S1 family. Kallikrein subfamily.
Function for KLK15 Gene
Molecular function for KLK15 Gene
- UniProtKB/Swiss-Prot Function:
- Protease whose physiological substrate is not yet known.
Enzyme Numbers (IUBMB) for KLK15 Gene
Phenotypes From GWAS Catalog for KLK15 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004252 | serine-type endopeptidase activity | NAS | 11010966 |
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0008233 | peptidase activity | IEA | -- |
| GO:0008236 | serine-type peptidase activity | TAS | 8018728 |
| GO:0016787 | hydrolase activity | IEA | -- |
Phenotypes for KLK15 Gene
- GenomeRNAi human phenotypes for KLK15:
-
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- Lamellipodia cells
- Decreased viability in esophageal squamous lineage
- Increased shRNA abundance (Z-score > 2)
- Dynamic nuclei (hole, folded or small irregular)
- Decreased shRNA abundance (Z-score < -2)
- Increased viability with MLN4924 (a NAE inhibitor)
Animal Model Products
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Taconic Biosciences Mouse Models for KLK15
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-
-
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-
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-
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- genomics-online: shRNA clones - Search results for 109 available Kallikrein 15 gene related products
- Overview of 109 available Kallikrein 15 gene related products
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ViGene Biosciences ready-to-package AAV shRNAs for KLK15 gene
Clone Products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for 109 available Kallikrein 15 gene related products
- Overview of 109 available Kallikrein 15 gene related products
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-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
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Horizon Cell Lines for KLK15
-
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-
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-
ViGene Biosciences ready-to-package AAV shRNAs for KLK15 gene
No data available for Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for KLK15 Gene
Localization for KLK15 Gene
Subcellular locations from UniProtKB/Swiss-Prot for KLK15 Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| mitochondrion | 1 |
| nucleus | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for KLK15 Gene
Pathways & Interactions for KLK15 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Collagen chain trimerization | ||
| 2 | MSP-RON Signaling | ||
| 3 | PPAR Alpha Pathway | ||
Pathways by source for KLK15 Gene
1 BioSystems pathway for KLK15 Gene
3 Qiagen pathways for KLK15 Gene
Interacting Proteins for KLK15 Gene
Selected Interacting proteins:
Q9H2R5-KLK15_HUMAN
ENSP00000469315
for KLK15 Gene via
IID
STRING
UniProtKB
MINT
| Symbol | External ID(s) | Details |
|---|---|---|
| ABHD3 | ||
| APP | ||
| EPPIN-WFDC6 | ||
| FSTL4 | ||
| FSTL5 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006508 | proteolysis | IEA | -- |
No data available for SIGNOR curated interactions for KLK15 Gene
Transcripts for KLK15 Gene
mRNA/cDNA for KLK15 Gene
- (12) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (19) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for KLK15 Gene
CRISPR Products
-
OriGene CRISPR knockouts for KLK15
- Applied Biological Materials CRISPR for KLK15
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for KLK15
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miRNA Products
- Search ViGene Biosciences for KLK15
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for KLK15
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- genomics-online: shRNA clones - Search results for 109 available Kallikrein 15 gene related products
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-
ViGene Biosciences ready-to-package AAV shRNAs for KLK15 gene
Clone Products
-
OriGene ORF clones in human for KLK15
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for KLK15
- VectorBuilder custom plasmid, inducible vectors for KLK15
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for KLK15
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for 109 available Kallikrein 15 gene related products
- Overview of 109 available Kallikrein 15 gene related products
- orf clones - Search results for 109 available Kallikrein 15 gene related products
- Overview of 109 available Kallikrein 15 gene related products
- Applied Biological Materials Clones for KLK15
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||
| SP2: | |||||||||||||||||
| SP3: | |||||||||||||||||
| SP4: | - | - |
Expression for KLK15 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Testis (Reproductive System)
- Leydig Cells Testis Interstitium
mRNA differential expression in normal tissues according to GTEx for KLK15 Gene
This gene is overexpressed in Testis (x17.7), Colon - Transverse (x13.9), Prostate (x5.6), and Adrenal Gland (x4.6).
This gene is overexpressed in Monocytes (49.8) and Rectum (19.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for KLK15 Gene
NURSA nuclear receptor signaling pathways regulating expression of KLK15 Gene:
KLK15SOURCE GeneReport for Unigene cluster for KLK15 Gene:
Hs.567535mRNA Expression by UniProt/SwissProt for KLK15 Gene:
Q9H2R5-KLK15_HUMAN
Tissue specificity:
Highest expression in the thyroid gland. Also expressed in the prostate, salivary, and adrenal glands and in the colon testis and kidney.
Evidence on tissue expression from TISSUES for KLK15 Gene
- Nervous system(4.2)
Primer Products
-
OriGene qPCR primer pairs for KLK15
- genomics-online: primer clones - Search results for 109 available Kallikrein 15 gene related products
- Overview of 109 available Kallikrein 15 gene related products
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for KLK15 Gene
Orthologs for KLK15 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | KLK15 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | KLK15 33 |
|
||
| cow (Bos Taurus) |
Mammalia | KLK15 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | LOC102553035 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Klk15 33 16 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | KLK15 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | KLK15 34 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | CG17239 35 |
|
|
- Species where no ortholog for KLK15 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for KLK15 Gene
Paralogs for KLK15 Gene
(63) SIMAP similar genes for KLK15 Gene using alignment to 7 proteins:
- KLK11
- KLK8
- KLK6
- KLK9
- PRSS1
- KLK12
- TRY8
- PRSS2
- KLK5
- PRSS3
- CELA3A
- KLK7
- KLK13
- KLK4
- KLK14
- KLK1
- KLK10
- CTRL
- CTSG
- GZMH
- ELANE
- ELA2A
- LOC136242
- CELA3B
- GZMA
- KLK2
- GZMB
- OVCH1
- CELA2A
- ELA2B
- CELA2B
- CELA1
- CTRB1
- PRSS41
- ELA3A
- CTRC
- GZMK
- CMA1
- TMPRSS5
- serase-1B
- PRSS45
- HABP2
- GZMM
- DF
- CTRB2
- PRTN3
- ST14
- PRSS56
- CFD
- PRSS55
- TPSAB1
- TMPRSS3
- F12
- TPSB2
- TMPRSS2
- factor IX F9
- F9 p22
- TMPRSS15
- APS
- tryptaseC
- TPSG1
- TPSD1
- TMPRSS9
Variants for KLK15 Gene
| SNP ID | Clin | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| VAR_036298 | A breast cancer sample | p.Ala137Thr | |||
| rs1000290070 | -- | 50,831,936(-) | C/T | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000426976 | -- | 50,831,595(-) | A/T | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000549668 | -- | 50,825,501(-) | C/T | 3_prime_UTR_variant, downstream_transcript_variant, genic_downstream_transcript_variant, non_coding_transcript_variant | |
| rs1000704134 | -- | 50,831,247(-) | CCCC/CCC | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1058e212 | CNV | loss | 25503493 |
| dgv1802n106 | CNV | deletion | 24896259 |
| dgv203n21 | CNV | loss | 19592680 |
| dgv204n21 | CNV | loss | 19592680 |
| esv2422090 | CNV | deletion | 20811451 |
| esv2662649 | CNV | deletion | 23128226 |
| esv2763099 | CNV | loss | 21179565 |
| esv3556538 | CNV | deletion | 23714750 |
| esv3583463 | CNV | loss | 25503493 |
| esv3583464 | CNV | loss | 25503493 |
| esv3644656 | CNV | loss | 21293372 |
| esv3644657 | CNV | gain | 21293372 |
| nsv1140251 | OTHER | inversion | 24896259 |
| nsv2531 | CNV | deletion | 18451855 |
| nsv515608 | CNV | loss | 19592680 |
Residual Variation Intolerance Score:
82.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.80;
47.47% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for KLK15 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KLK15 Gene
Disorders for KLK15 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| prostate cancer |
|
Search KLK15 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for KLK15
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for KLK15 Gene
Publications for KLK15 Gene
- Molecular cloning of the human kallikrein 15 gene (KLK15). Up-regulation in prostate cancer. (PMID: 11010966) Yousef GM … Diamandis EP (The Journal of biological chemistry 2001) 2 3 4 22 58
- The androgen-regulated gene human kallikrein 15 (KLK15) is an independent and favourable prognostic marker for breast cancer. (PMID: 12439720) Yousef GM … Diamandis EP (British journal of cancer 2002) 2 3 22 58
- Replication of prostate cancer risk loci on 8q24, 11q13, 17q12, 19q33, and Xp11 in African Americans. (PMID: 19902474) Hooker S … Kittles RA (The Prostate 2010) 3 44 58
- Risk of meningioma and common variation in genes related to innate immunity. (PMID: 20406964) Rajaraman P … Inskip PD (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010) 3 44 58
- Blood biomarker levels to aid discovery of cancer-related single-nucleotide polymorphisms: kallikreins and prostate cancer. (PMID: 20424135) Klein RJ … Lilja H (Cancer prevention research (Philadelphia, Pa.) 2010) 3 44 58
Products for KLK15 Gene
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- Taconic Biosciences Mouse Models for KLK15
- Find your next knockout model in the Taconic Knockout Repository
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 76 available Kallikrein 15 Antibodies ranked by validation data
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- genomics-online: cdna clones - Search results for 109 available Kallikrein 15 gene related products
- Overview of 109 available Kallikrein 15 gene related products
- orf clones - Search results for 109 available Kallikrein 15 gene related products
- Overview of 109 available Kallikrein 15 gene related products
- genomics-online: gRNA clones - Search results for 109 available Kallikrein 15 gene related products
- Overview of 109 available Kallikrein 15 gene related products
- genomics-online: primer clones - Search results for 109 available Kallikrein 15 gene related products
- Overview of 109 available Kallikrein 15 gene related products
- genomics-online: shRNA clones - Search results for 109 available Kallikrein 15 gene related products
- Overview of 109 available Kallikrein 15 gene related products
Sources for KLK15 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
