This gene encodes a member of the kallikrein subfamily of serine proteases that have diverse physiological functions such as regulation of blood pressure and desquamation. The altered expression of this gene is implicated in the progression of different cancers including breast and prostate tumors. The encoded protein is a precursor that is proteolytically processed to generate... See more...

Aliases for KLK14 Gene

Aliases for KLK14 Gene

  • Kallikrein Related Peptidase 14 2 3 5
  • KLK-L6 2 3 4
  • Kallikrein-Like Protein 6 3 4
  • Kallikrein-14 3 4
  • Kallikrein 14 2
  • EC 3.4.21.- 4
  • EC 3.4.21 51
  • KLK14 5
  • KLKL6 4
  • HK14 4

External Ids for KLK14 Gene

Previous GeneCards Identifiers for KLK14 Gene

  • GC19M052211
  • GC19M051941
  • GC19M056256
  • GC19M056272
  • GC19M051580
  • GC19M047914

Summaries for KLK14 Gene

Entrez Gene Summary for KLK14 Gene

  • This gene encodes a member of the kallikrein subfamily of serine proteases that have diverse physiological functions such as regulation of blood pressure and desquamation. The altered expression of this gene is implicated in the progression of different cancers including breast and prostate tumors. The encoded protein is a precursor that is proteolytically processed to generate the functional enzyme. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

GeneCards Summary for KLK14 Gene

KLK14 (Kallikrein Related Peptidase 14) is a Protein Coding gene. Diseases associated with KLK14 include Netherton Syndrome and Breast Cancer. Among its related pathways are Keratinization and Collagen chain trimerization. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase activity. An important paralog of this gene is KLK5.

UniProtKB/Swiss-Prot Summary for KLK14 Gene

  • Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. May function in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3. May function through desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface. May be involved in several aspects of tumor progression including growth, invasion and angiogenesis.

Gene Wiki entry for KLK14 Gene

Additional gene information for KLK14 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for KLK14 Gene

Genomics for KLK14 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for KLK14 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J051016 Promoter/Enhancer 1.6 EPDnew Ensembl ENCODE 10.4 +65.6 65622 4 RNF2 CTCF TEAD4 PRDM10 ZNF512 IKZF1 ZNF692 ETV6 ZNF300 PRDM1 KLK10 ZNF175 ZNF577 ZNF615 ZNF649 ZNF350 ZNF473 LRRC4B POLD1 SPACA6
GH19J051136 Promoter/Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 10.6 -53.7 -53726 3.7 ARHGAP35 IKZF1 MTA2 PKNOX1 ZNF24 REST POLR2A MNT ZNF766 NFE2 ENSG00000267990 lnc-SIGLEC9-1 SIGLEC17P CTU1 SIGLEC9 KLK14 KLK10 SIGLEC7 SIGLEC10 CD33
GH19J051064 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE CraniofacialAtlas 7.5 +19.1 19144 1.4 KDM1A MTA1 NR2C1 HDAC1 SOX6 GATAD2B NRF1 SOX13 THRA ZNF766 KLK13 LOC107985341 LRRC4B SHANK1 KLK14 ENSG00000268390 KLK12
GH19J050537 Enhancer 1.1 ENCODE dbSUPER 9.5 +546.4 546366 0.1 CREB1 CTCF TEAD4 IKZF1 RFX5 JUND ZNF143 MTA2 ZSCAN4 REST ASPDH JOSD2 LRRC4B GPR32 SNORD88A SNORD88B SNORD88C NAPSA NR1H2 C19orf48
GH19J050931 Enhancer 0.9 Ensembl ENCODE 10.2 +151.4 151422 2.9 SP1 CTBP1 NFE2 ZNF316 MAFF MAFK MAFG EHMT2 CTCF FOXA1 KLK4 KLK6 KLK2 KLK15 KLK1 LINC01869 C19orf48 SNORD88C KLK14 CTU1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around KLK14 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for KLK14

Top Transcription factor binding sites by QIAGEN in the KLK14 gene promoter:
  • AhR
  • C/EBPalpha
  • CHOP-10
  • GATA-1
  • NRSF form 2
  • p300
  • p53
  • Pax-5
  • RREB-1
  • YY1

Genomic Locations for KLK14 Gene

Genomic Locations for KLK14 Gene
chr19:51,077,494-51,084,245
(GRCh38/hg38)
Size:
6,752 bases
Orientation:
Minus strand
chr19:51,580,752-51,587,502
(GRCh37/hg19)
Size:
6,751 bases
Orientation:
Minus strand

Genomic View for KLK14 Gene

Genes around KLK14 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KLK14 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KLK14 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KLK14 Gene

Proteins for KLK14 Gene

  • Protein details for KLK14 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9P0G3-KLK14_HUMAN
    Recommended name:
    Kallikrein-14
    Protein Accession:
    Q9P0G3
    Secondary Accessions:
    • A7UNK5
    • Q1RMZ2
    • Q6B089

    Protein attributes for KLK14 Gene

    Size:
    267 amino acids
    Molecular mass:
    29122 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAD50773.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAG23260.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAK48523.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAK48524.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=ABU63131.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for KLK14 Gene

Selected DME Specific Peptides for KLK14 Gene

Q9P0G3:
  • GDSGGPL
  • SGGPLVC
  • DSCQGDSGG
  • CQGDSGGP

Post-translational modifications for KLK14 Gene

  • Proteolytic cleavage of the activation peptide produces the active enzyme.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KLK14 Gene

Domains & Families for KLK14 Gene

Gene Families for KLK14 Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Enzymes
  • Plasma proteins
  • Predicted secreted proteins

Protein Domains for KLK14 Gene

InterPro:
Blocks:
  • Serine protease, trypsin family
  • Chymotrypsin serine protease family (S1) signature
ProtoNet:

Suggested Antigen Peptide Sequences for KLK14 Gene

GenScript: Design optimal peptide antigens:
  • Kallikrein-like protein 6 (KLK14_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9P0G3

UniProtKB/Swiss-Prot:

KLK14_HUMAN :
  • Belongs to the peptidase S1 family. Kallikrein subfamily.
Family:
  • Belongs to the peptidase S1 family. Kallikrein subfamily.
genes like me logo Genes that share domains with KLK14: view

Function for KLK14 Gene

Molecular function for KLK14 Gene

UniProtKB/Swiss-Prot Function:
Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. May function in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3. May function through desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface. May be involved in several aspects of tumor progression including growth, invasion and angiogenesis.
UniProtKB/Swiss-Prot Induction:
Up-regulated by steroid hormone.
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=0.3 mM for S-2288 {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:17110383}; KM=0.2 mM for S-2222 {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:17110383}; KM=0.2 mM for S-2302 {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:17110383}; KM=0.7 mM for S-2586 {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:17110383}; KM=0.045 mM for Gln-Ala-Arg synthetic peptide {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:17110383}; KM=0.043 mM for Val-Pro-Arg synthetic peptide {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:17110383}; KM=0.09 mM for Pro-Phe-Arg synthetic peptide {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:17110383}; KM=0.278 mM for Phe-Ser-Arg synthetic peptide {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:17110383}; KM=0.0577 mM for Leu-Gly-Arg synthetic peptide {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:17110383}; KM=0.139 mM for Gln-Gly-Arg synthetic peptide {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:17110383}; KM=0.173 mM for Gly-Pro-Arg synthetic peptide {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:17110383}; KM=0.0268 mM for Gln-Arg-Arg synthetic peptide {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:17110383}; KM=0.130 mM for Gly-Gly-Arg synthetic peptide {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:17110383}; KM=0.578 mM for Val-Leu-Lys synthetic peptide {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:17110383}; Note=Has a higher catalytic efficiency for the trypsin-like enzyme substrates S-2288, S-2222 and S-2302 compared to S-2586 a chymotrypsin-like enzyme substrate. Has a lower catalytic activity compared to trypsin towards S-2288, S-2222 and S-2302. Cleaves preferentially after Arg residues.; pH dependence: Optimum pH is 8.0. {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:17110383};
UniProtKB/Swiss-Prot EnzymeRegulation:
Inhibited by SERPINA1, SERPINC1, SERPINE1, SERPINF2, aprotinin, soybean, trypsin inhibitor and leupeptin. Inhibited by serine protease inhibitor SPINK5. Has an autoproteolytic activity which may have a regulatory effect. Activated by citrate and inhibited by zinc and to a lower extent by manganese.

Enzyme Numbers (IUBMB) for KLK14 Gene

Phenotypes From GWAS Catalog for KLK14 Gene

Gene Ontology (GO) - Molecular Function for KLK14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004252 serine-type endopeptidase activity NAS 10969073
GO:0008233 peptidase activity IEA --
GO:0008236 serine-type peptidase activity IEA --
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with KLK14: view
genes like me logo Genes that share phenotypes with KLK14: view

Animal Models for KLK14 Gene

MGI Knock Outs for KLK14:
  • Klk14 Klk14<tm1.1(KOMP)Vlcg>

Animal Model Products

  • Taconic Biosciences Mouse Models for KLK14

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KLK14

No data available for Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for KLK14 Gene

Localization for KLK14 Gene

Subcellular locations from UniProtKB/Swiss-Prot for KLK14 Gene

Secreted, extracellular space.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KLK14 gene
Compartment Confidence
extracellular 5
plasma membrane 2
cytoskeleton 1
mitochondrion 1
nucleus 1
endoplasmic reticulum 1
endosome 1
cytosol 1
lysosome 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for KLK14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005615 extracellular space IEA,IDA 15654974
GO:0030141 secretory granule IBA 21873635
genes like me logo Genes that share ontologies with KLK14: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for KLK14 Gene

Pathways & Interactions for KLK14 Gene

PathCards logo

SuperPathways for KLK14 Gene

SuperPathway Contained pathways
1 Collagen chain trimerization
.48
.46
2 Keratinization
3 MSP-RON Signaling
-
4 Developmental Biology
genes like me logo Genes that share pathways with KLK14: view

Pathways by source for KLK14 Gene

3 Qiagen pathways for KLK14 Gene
  • Blood Coagulation Cascade
  • Intrinsic Prothrombin Activation Pathway
  • MSP-RON Signaling

Gene Ontology (GO) - Biological Process for KLK14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IDA 15654974
GO:0009566 fertilization IDA 18482984
GO:0045744 negative regulation of G protein-coupled receptor signaling pathway IDA 16885167
GO:0045745 positive regulation of G protein-coupled receptor signaling pathway IDA 16885167
GO:0048730 epidermis morphogenesis IBA,IDA 17158887
genes like me logo Genes that share ontologies with KLK14: view

No data available for SIGNOR curated interactions for KLK14 Gene

Drugs & Compounds for KLK14 Gene

(1) Drugs for KLK14 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(1) Additional Compounds for KLK14 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with KLK14: view

Transcripts for KLK14 Gene

mRNA/cDNA for KLK14 Gene

3 REFSEQ mRNAs :
9 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KLK14

Alternative Splicing Database (ASD) splice patterns (SP) for KLK14 Gene

No ASD Table

Relevant External Links for KLK14 Gene

GeneLoc Exon Structure for
KLK14

Expression for KLK14 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for KLK14 Gene

mRNA differential expression in normal tissues according to GTEx for KLK14 Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x6.6), Vagina (x4.5), and Skin - Not Sun Exposed (Suprapubic) (x4.3).

Protein differential expression in normal tissues from HIPED for KLK14 Gene

This gene is overexpressed in Saliva (68.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for KLK14 Gene



Protein tissue co-expression partners for KLK14 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for KLK14

SOURCE GeneReport for Unigene cluster for KLK14 Gene:

Hs.283925

mRNA Expression by UniProt/SwissProt for KLK14 Gene:

Q9P0G3-KLK14_HUMAN
Tissue specificity: Highly expressed in CNS, bone marrow and fetal liver. Also expressed in breast, thyroid, kidney, colon, pancreas, spleen, prostate, uterus, small intestine, placenta and skeletal muscle. Among 40 tissues tested, the highest expression is detected in skin followed by breast and prostate (at protein level). Expressed in stratum corneum by sweat ducts and sweat glands and detected in sweat (at protein level).

Evidence on tissue expression from TISSUES for KLK14 Gene

  • Lung(4.4)
  • Skin(2.4)
  • Blood(2.3)
  • Nervous system(2.1)
genes like me logo Genes that share expression patterns with KLK14: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for KLK14 Gene

Orthologs for KLK14 Gene

This gene was present in the common ancestor of animals.

Orthologs for KLK14 Gene

Organism Taxonomy Gene Similarity Type Details
Dog
(Canis familiaris)
Mammalia KLK14 30 31
  • 83.4 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia KLK14 30 31
  • 80.53 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Klk14 30
  • 77.2 (n)
Mouse
(Mus musculus)
Mammalia Klk14 30 17 31
  • 76.93 (n)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia KLK14 31
  • 64 (a)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia KLK14 31
  • 60 (a)
OneToOne
Fruit Fly
(Drosophila melanogaster)
Insecta CG17239 32
  • 38 (a)
CG6041 32
  • 36 (a)
Species where no ortholog for KLK14 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for KLK14 Gene

ENSEMBL:
Gene Tree for KLK14 (if available)
TreeFam:
Gene Tree for KLK14 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for KLK14: view image

Paralogs for KLK14 Gene

Variants for KLK14 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for KLK14 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
734214 Likely Benign: not provided 51,078,909(-) G/A MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT
734215 Likely Benign: not provided 51,082,640(-) T/A INTRON_VARIANT
808632 Likely Benign: not provided 51,082,721(-) C/T SPLICE_DONOR_VARIANT
rs2569490 - p.Arg64His
rs2569491 - p.His45Tyr

Additional dbSNP identifiers (rs#s) for KLK14 Gene

Structural Variations from Database of Genomic Variants (DGV) for KLK14 Gene

Variant ID Type Subtype PubMed ID
esv2718766 CNV deletion 23290073
esv2718767 CNV deletion 23290073
esv34104 CNV loss 18971310
nsv1140251 OTHER inversion 24896259
nsv953606 CNV deletion 24416366

Variation tolerance for KLK14 Gene

Residual Variation Intolerance Score: 93.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.36; 88.42% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for KLK14 Gene

Human Gene Mutation Database (HGMD)
KLK14
SNPedia medical, phenotypic, and genealogical associations of SNPs for
KLK14

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KLK14 Gene

Disorders for KLK14 Gene

MalaCards: The human disease database

(3) MalaCards diseases for KLK14 Gene - From: DISEASES and Novoseek

Disorder Aliases PubMed IDs
netherton syndrome
  • neth
breast cancer
  • breast lobular carcinoma
autosomal recessive congenital ichthyosis
  • arci
- elite association - COSMIC cancer census association via MalaCards
Search KLK14 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for KLK14

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with KLK14: view

No data available for UniProtKB/Swiss-Prot and Genatlas for KLK14 Gene

Publications for KLK14 Gene

  1. Major role of human KLK14 in seminal clot liquefaction. (PMID: 18482984) Emami N … Diamandis EP (The Journal of biological chemistry 2008) 3 4 23
  2. A potential role for multiple tissue kallikrein serine proteases in epidermal desquamation. (PMID: 17158887) Borgoño CA … Diamandis EP (The Journal of biological chemistry 2007) 3 4 23
  3. Enzymatic profiling of human kallikrein 14 using phage-display substrate technology. (PMID: 15843175) Felber LM … Deperthes D (Biological chemistry 2005) 3 4 23
  4. Cloning of a new member of the human kallikrein gene family, KLK14, which is down-regulated in different malignancies. (PMID: 11309303) Yousef GM … Diamandis EP (Cancer research 2001) 3 4 23
  5. Blood biomarker levels to aid discovery of cancer-related single-nucleotide polymorphisms: kallikreins and prostate cancer. (PMID: 20424135) Klein RJ … Lilja H (Cancer prevention research (Philadelphia, Pa.) 2010) 3 41

Products for KLK14 Gene

  • Boster Bio Antibodies for KLK14
  • Boster Bio ELISA Kits for KLK14
  • Signalway ELISA kits for KLK14

Sources for KLK14 Gene