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Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may pl... See more...
Aliases for KLK10 Gene
Aliases for KLK10 Gene
- Kallikrein Related Peptidase 10 2 3 5
- NES1 2 3 4
- Normal Epithelial Cell-Specific 1 3 4
- Protease Serine-Like 1 3 4
- Kallikrein-10 3 4
- PRSSL1 3 4
- Breast Normal Epithelial Cell Associated Serine Protease 3
- Kallikrein 10 Protein 12 3
- Kallikrein 10 Protein 13 3
- Kallikrein 10 Protein 1 3
- Kallikrein 10 Protein 2 3
External Ids for KLK10 Gene
- HGNC: 6358
- NCBI Entrez Gene: 5655
- Ensembl: ENSG00000129451
- OMIM®: 602673
- UniProtKB/Swiss-Prot: O43240
Previous HGNC Symbols for KLK10 Gene
- PRSSL1
Previous GeneCards Identifiers for KLK10 Gene
- GC19M052148
- GC19M051877
- GC19M056193
- GC19M056209
- GC19M051516
- GC19M047848
Summaries for KLK10 Gene
-
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
GeneCards Summary for KLK10 Gene
KLK10 (Kallikrein Related Peptidase 10) is a Protein Coding gene. Diseases associated with KLK10 include Gastroesophageal Adenocarcinoma and Breast Cancer. Among its related pathways are Collagen chain trimerization and MSP-RON Signaling. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase activity and serine-type peptidase activity. An important paralog of this gene is F12.
UniProtKB/Swiss-Prot Summary for KLK10 Gene
-
Has a tumor-suppressor role for NES1 in breast and prostate cancer.
Additional gene information for KLK10 Gene
- HGNC (6358)
- NCBI Entrez Gene (5655)
- Ensembl (ENSG00000129451)
- OMIM® (602673)
- UniProtKB/Swiss-Prot (O43240)
- Open Targets Platform(ENSG00000129451)
- Monarch Initiative
- Search for KLK10 at DataMed
- Search for KLK10 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for KLK10 Gene
Genomics for KLK10 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for KLK10 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around KLK10 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for KLK10
- Top Transcription factor binding sites by QIAGEN in the KLK10 gene promoter:
-
- ER-alpha
- NF-E2
- NF-E2 p45
- ZID
Genomic Locations for KLK10 Gene
Latest Assembly
- chr19:51,012,739-51,020,175
- (GRCh38/hg38)
- Size:
- 7,437 bases
- Orientation:
- Minus strand
Previous Assembly
- chr19:51,515,995-51,523,353
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 7,359 bases
- Orientation:
- Minus strand
- chr19:51,515,995-51,523,431
- (GRCh37/hg19 by Ensembl)
- Size:
- 7,437 bases
- Orientation:
- Minus strand
Genomic View for KLK10 Gene
Genes around KLK10 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.41 by HGNC
- 19q13.41 by Entrez Gene
- 19q13.41 by Ensembl
KLK10 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for KLK10 Gene
Proteins for KLK10 Gene
-
Protein details for KLK10 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O43240-KLK10_HUMAN
- Recommended name:
- Kallikrein-10
- Protein Accession:
- O43240
- A6NC12
- Q53YL3
- Q99920
- Q9GZW9
Protein attributes for KLK10 Gene
- Size:
- 276 amino acids
- Molecular mass:
- 30170 Da
- Quaternary structure:
- No Data Available
Protein Expression for KLK10 Gene
Selected DME Specific Peptides for KLK10 Gene
- O43240:
-
- VLTAAHC
- WVLTAAH
- QGILSWG
- SGGPLVC
Post-translational modifications for KLK10 Gene
Other Protein References for KLK10 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences KLK10 / Kallikrein 10 Antibody
-
Custom Antibody ServicesOriGene Antibodies for KLK10
- Novus Biologicals Antibodies for KLK10
-
Abcam antibodies for KLK10
- Invitrogen Antibodies for KLK10 (AFLGC-KLK10)
- antibodies-online: Show 23 available Kallikrein 10 Antibodies ranked by validation data
- Compare Top Kallikrein 10 Antibodies
-
Recommended
- 12 IF (p) Antibodies (anti-mouse)
- 9 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-rat)
- 9 WB Antibodies (anti-rat)
- 84 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 4 IHC Antibodies (anti-human)
- 3 IP Antibodies (anti-human)
- 2 RIA Antibodies (anti-human)
- 1 FACS Antibody (anti-human)
-
Custom Antibody ServicesProSci Antibodies for KLK10
-
Santa Cruz Biotechnology (SCBT) Antibodies for KLK10
Protein products for research
- G Biosciences Human Kallikrein 10/KLK10, Liquid
- RayBiotech Recombinant Human Kallikrein-10/KLK-10
- Search Origene for MassSpec and Protein Over-expression Lysates for KLK10
- Origene Custom Protein Services for KLK10
- ProSpec Recombinant Proteins for KLK10
-
ProSci Proteins for KLK10
-
Abcam proteins for KLK10
Domains & Families for KLK10 Gene
Gene Families for KLK10 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Enzymes
- Predicted secreted proteins
Protein Domains for KLK10 Gene
- InterPro:
- Blocks:
-
- Serine protease, trypsin family
- Chymotrypsin serine protease family (S1) signature
- ProtoNet:
Suggested Antigen Peptide Sequences for KLK10 Gene
- GenScript: Design optimal peptide antigens:
-
- Protease serine-like 1 (KLK10_HUMAN)
- cDNA FLJ76060, highly similar to Homo sapiens kallikrein 10 (KLK10), transcript variant 1, mRNA (Q6ICR6_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O43240- Family:
-
- Belongs to the peptidase S1 family. Kallikrein subfamily.
Function for KLK10 Gene
Molecular function for KLK10 Gene
- UniProtKB/Swiss-Prot Function:
- Has a tumor-suppressor role for NES1 in breast and prostate cancer.
Enzyme Numbers (IUBMB) for KLK10 Gene
Phenotypes From GWAS Catalog for KLK10 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004252 | serine-type endopeptidase activity | IEA | -- |
| GO:0008233 | peptidase activity | IEA | -- |
| GO:0008236 | serine-type peptidase activity | TAS | 8764136 |
| GO:0016787 | hydrolase activity | IEA | -- |
Phenotypes for KLK10 Gene
Animal Models for research
-
Taconic Biosciences Mouse Models for KLK10
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for KLK10 - Starting at $85 >
- * KLK10 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for KLK10
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for KLK10
-
Santa Cruz Biotechnology (SCBT) CRISPR for KLK10
miRNA for KLK10 Gene
- miRTarBase miRNAs that target KLK10
-
- hsa-miR-224-5p (MIRT000454)
- hsa-let-7f-5p (MIRT000455)
- hsa-miR-375 (MIRT019672)
- hsa-miR-6788-5p (MIRT474376)
- hsa-miR-30c-2-3p (MIRT474378)
- hsa-miR-30c-1-3p (MIRT474379)
- hsa-miR-6778-5p (MIRT474380)
- hsa-miR-1233-5p (MIRT474381)
- hsa-miR-8085 (MIRT474382)
- hsa-miR-6731-5p (MIRT474383)
- hsa-miR-6878-5p (MIRT474384)
- hsa-miR-4261 (MIRT474385)
- hsa-miR-6088 (MIRT474386)
- hsa-miR-143-3p (MIRT474387)
- hsa-miR-4770 (MIRT474388)
- hsa-miR-6770-5p (MIRT474389)
- hsa-miR-1253 (MIRT474390)
- hsa-miR-4795-5p (MIRT474391)
- hsa-miR-1252-5p (MIRT474392)
- hsa-miR-194-3p (MIRT474393)
- hsa-miR-140-5p (MIRT474394)
- hsa-miR-6880-5p (MIRT569861)
- hsa-miR-6763-5p (MIRT569862)
- hsa-miR-6825-5p (MIRT569863)
- hsa-miR-3150a-3p (MIRT569864)
- hsa-miR-939-5p (MIRT569865)
- hsa-miR-1343-5p (MIRT569866)
- hsa-miR-3175 (MIRT569867)
- hsa-miR-7106-5p (MIRT569868)
- hsa-miR-766-5p (MIRT569869)
- hsa-miR-6077 (MIRT569870)
- hsa-miR-8082 (MIRT569871)
- hsa-miR-4534 (MIRT569872)
- hsa-miR-3605-5p (MIRT569873)
- hsa-miR-4700-5p (MIRT569874)
- hsa-miR-8089 (MIRT569875)
- hsa-miR-4667-5p (MIRT569876)
- hsa-miR-2392 (MIRT569877)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for KLK10
- Browse OriGene Inhibitory RNA Products For KLK10
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KLK10
Clone products for research
- Applied Biological Materials (abm): Clones for KLK10 - Starting at $45 >
- * KLK10 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
-
- MG203758
- MR203758
- MR203758L3
- MR203758L4
- RC201139
- RC201139L3
- RC201139L4
- RC218327
- RC218327L1
- RC218327L2
- RC218327L3
- RC218327L4
- RC218377
- RC218377L3
- RC218377L4
- RG201139
- RG218327
- RG218377
- RR214984
- RR214984L3
- RR214984L4
- MR203758L3V
- MR203758L4V
- RC201139L3V
- RC201139L4V
- RC218327L1V
- RC218327L2V
- RC218327L3V
- RC218327L4V
- RC218377L3V
- RC218377L4V
- RR214984L3V
- RR214984L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for KLK10
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for KLK10
Cell Lines for research
-
Horizon Cell Lines for KLK10
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KLK10 Gene
Localization for KLK10 Gene
Subcellular locations from UniProtKB/Swiss-Prot for KLK10 Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| plasma membrane | 3 |
| cytoskeleton | 3 |
| nucleus | 3 |
| cytosol | 3 |
| mitochondrion | 2 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS,IEA | -- |
| GO:0030141 | secretory granule | IBA | 21873635 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for KLK10 Gene
Pathways & Interactions for KLK10 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Collagen chain trimerization |
Intrinsic Prothrombin Activation Pathway
.48
|
Blood Coagulation Cascade
.46
|
| 2 | MSP-RON Signaling |
MSP-RON Signaling
-
|
|
Pathways by source for KLK10 Gene
3 Qiagen pathways for KLK10 Gene
- Blood Coagulation Cascade
- Intrinsic Prothrombin Activation Pathway
- MSP-RON Signaling
Interacting Proteins for KLK10 Gene
GPS-Prot Interaction Network for KLK10
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006508 | proteolysis | IEA | -- |
| GO:0007049 | cell cycle | IEA | -- |
No data available for SIGNOR curated interactions for KLK10 Gene
Drugs & Compounds for KLK10 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Drug products for research
- G Biosciences Human Kallikrein 10/KLK10, Liquid
- RayBiotech Recombinant Human Kallikrein-10/KLK-10
Transcripts for KLK10 Gene
mRNA/cDNA for KLK10 Gene
- 3 REFSEQ mRNAs :
- 30 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000309958 3111 nts (view in UCSC)
- ENST00000358789 2984 nts (view in UCSC)
- ENST00000391805 3006 nts (view in UCSC)
- ENST00000599077 549 nts (view in UCSC)
- ENST00000599987 557 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for KLK10 - Starting at $85 >
- * KLK10 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for KLK10
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for KLK10
-
Santa Cruz Biotechnology (SCBT) CRISPR for KLK10
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for KLK10
- Browse OriGene Inhibitory RNA Products For KLK10
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KLK10
Clone products for research
- Applied Biological Materials (abm): Clones for KLK10 - Starting at $45 >
- * KLK10 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
-
- MG203758
- MR203758
- MR203758L3
- MR203758L4
- RC201139
- RC201139L3
- RC201139L4
- RC218327
- RC218327L1
- RC218327L2
- RC218327L3
- RC218327L4
- RC218377
- RC218377L3
- RC218377L4
- RG201139
- RG218327
- RG218377
- RR214984
- RR214984L3
- RR214984L4
- MR203758L3V
- MR203758L4V
- RC201139L3V
- RC201139L4V
- RC218327L1V
- RC218327L2V
- RC218327L3V
- RC218327L4V
- RC218377L3V
- RC218377L4V
- RR214984L3V
- RR214984L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for KLK10
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for KLK10
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||
| SP2: | |||||||||||||||||
| SP3: |
Relevant External Links for KLK10 Gene
- GeneLoc Exon Structure for
- KLK10
Expression for KLK10 Gene
mRNA differential expression in normal tissues according to GTEx for KLK10 Gene
This gene is overexpressed in Esophagus - Mucosa (x23.1), Vagina (x6.8), Cervix - Ectocervix (x6.5), and Minor Salivary Gland (x4.4).
This gene is overexpressed in Cervix (48.1), Saliva (8.2), and Hair follicle (7.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for KLK10 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for KLK10
SOURCE GeneReport for Unigene cluster for KLK10 Gene:
Hs.275464mRNA Expression by UniProt/SwissProt for KLK10 Gene:
O43240-KLK10_HUMAN
Tissue specificity:
Expressed in breast, ovary and prostate.
Evidence on tissue expression from TISSUES for KLK10 Gene
- Pancreas(2.8)
- Skin(2.7)
- Intestine(2.3)
- Kidney(2.2)
- Nervous system(2.1)
- Lung(2.1)
Primer products for research
-
OriGene qPCR primer pairs for KLK10
-
OriGene qPCR primer pairs and template standards for KLK10
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for KLK10 Gene
Orthologs for KLK10 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | KLK10 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | KLK10 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | KLK10 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Klk10 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Klk10 30 |
|
||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | KLK10 31 |
|
OneToOne |
- Species where no ortholog for KLK10 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for KLK10 Gene
- ENSEMBL:
- Gene Tree for KLK10 (if available)
- TreeFam:
- Gene Tree for KLK10 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for KLK10: view image
Paralogs for KLK10 Gene
Paralogs for KLK10 Gene
(38) SIMAP similar genes for KLK10 Gene using alignment to 4 proteins:
- KLK10_HUMAN
- M0R132_HUMAN
- M0R2S4_HUMAN
- Q6ICR6_HUMAN
Variants for KLK10 Gene
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2677627 | CNV | deletion | 23128226 |
| nsv1140251 | OTHER | inversion | 24896259 |
| nsv579961 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
56% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.66;
72.84% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for KLK10 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- KLK10
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KLK10 Gene
Disorders for KLK10 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| gastroesophageal adenocarcinoma |
|
|
| breast cancer |
|
|
| ovarian cancer |
|
|
| prostate cancer |
|
|
| leukemia, acute lymphoblastic |
|
|
Search KLK10 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for KLK10
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for KLK10 Gene
Publications for KLK10 Gene
- Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression. (PMID: 8764136) Liu XL … Band V (Cancer research 1996) 2 3 4 23
- Identification of new splice variants and differential expression of the human kallikrein 10 gene, a candidate cancer biomarker. (PMID: 16103744) Yousef GM … Diamandis EP (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2005) 3 4 23
- Identification of single nucleotide polymorphisms in the human kallikrein 10 (KLK10) gene and their association with prostate, breast, testicular, and ovarian cancers. (PMID: 11920956) Bharaj BB … Diamandis EP (The Prostate 2002) 3 23 41
- The new human kallikrein gene family: implications in carcinogenesis. (PMID: 10675891) Diamandis EP … Obiezu CV (Trends in endocrinology and metabolism: TEM 2000) 2 3 23
- Structural characterization and mapping of the normal epithelial cell-specific 1 gene. (PMID: 9647736) Luo L … Diamandis EP (Biochemical and biophysical research communications 1998) 3 4 23
ExternalLinks
Products for KLK10 Gene
- Custom Antibody ServicesOriGene Antibodies for KLK10
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- OriGene qPCR primer pairs for KLK10
- OriGene qPCR primer pairs and template standards for KLK10
- OriGene CRISPR knockouts for KLK10
- MG203758
- MR203758
- MR203758L3
- MR203758L4
- RC201139
- RC201139L3
- RC201139L4
- RC218327
- RC218327L1
- RC218327L2
- RC218327L3
- RC218327L4
- RC218377
- RC218377L3
- RC218377L4
- RG201139
- RG218327
- RG218377
- RR214984
- RR214984L3
- RR214984L4
- MR203758L3V
- MR203758L4V
- RC201139L3V
- RC201139L4V
- RC218327L1V
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
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- Novus Biologicals Antibodies for KLK10
- Novus Biologicals proteins and lysates for KLK10
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- ProSpec Recombinant Proteins for KLK10
- Taconic Biosciences Mouse Models for KLK10
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for KLK10 (AFLGC-KLK10)
- VectorBuilder Custom and pre-made DNA vectors for KLK10 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for KLK10 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for KLK10 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for KLK10 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for KLK10
- antibodies-online: Show 23 available Kallikrein 10 Antibodies ranked by validation data
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- Recommended
- 12 IF (p) Antibodies (anti-mouse)
- 9 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-rat)
- 9 WB Antibodies (anti-rat)
- 84 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 4 IHC Antibodies (anti-human)
- 3 IP Antibodies (anti-human)
- 2 RIA Antibodies (anti-human)
- 1 FACS Antibody (anti-human)
- antibodies-online: Show 30 available Kallikrein 10 Elisa Kits ranked by validation data
- Compare Top Kallikrein 10 Elisa Kits
- antibodies-online: Show 11 available Kallikrein 10 Proteins ranked by validation data
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- Santa Cruz Biotechnology (SCBT) Antibodies for KLK10
- Search Santa Cruz Biotechnology (SCBT) for KLK10 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for KLK10
- Custom Antibody ServicesProSci Antibodies for KLK10
- ProSci Proteins for KLK10
- Horizon Cell Lines for KLK10
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for KLK10
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for KLK10
- Search GeneCopoeia for miRNA 3'UTR Target clone products for KLK10
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KLK10
Sources for KLK10 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB