Aliases for KLK10 Gene
External Ids for KLK10 Gene
Previous HGNC Symbols for KLK10 Gene
Previous GeneCards Identifiers for KLK10 Gene
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
GeneCards Summary for KLK10 Gene
KLK10 (Kallikrein Related Peptidase 10) is a Protein Coding gene. Diseases associated with KLK10 include Ovarian Cancer and Breast Cancer. Among its related pathways are MSP-RON Signaling and Collagen chain trimerization. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase activity and serine-type peptidase activity. An important paralog of this gene is KLK12.
UniProtKB/Swiss-Prot for KLK10 Gene
Has a tumor-suppressor role for NES1 in breast and prostate cancer.