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Aliases for KLHL8 Gene
Aliases for KLHL8 Gene
External Ids for KLHL8 Gene
- HGNC: 18644
- NCBI Entrez Gene: 57563
- Ensembl: ENSG00000145332
- OMIM®: 611967
- UniProtKB/Swiss-Prot: Q9P2G9
Previous GeneCards Identifiers for KLHL8 Gene
- GC04M088239
- GC04M088384
- GC04M088540
- GC04M088438
- GC04M088301
- GC04M088081
- GC04M083826
Summaries for KLHL8 Gene
GeneCards Summary for KLHL8 Gene
KLHL8 (Kelch Like Family Member 8) is a Protein Coding gene. Diseases associated with KLHL8 include Verrucous Papilloma and Enamel Caries. An important paralog of this gene is KLHL20.
UniProtKB/Swiss-Prot Summary for KLHL8 Gene
-
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN.
Additional gene information for KLHL8 Gene
- HGNC (18644)
- NCBI Entrez Gene (57563)
- Ensembl (ENSG00000145332)
- OMIM® (611967)
- UniProtKB/Swiss-Prot (Q9P2G9)
- Open Targets Platform(ENSG00000145332)
- Search for KLHL8 at DataMed
- Search for KLHL8 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for KLHL8 Gene
Genomics for KLHL8 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for KLHL8 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around KLHL8 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for KLHL8
- Top Transcription factor binding sites by QIAGEN in the KLHL8 gene promoter:
-
- Arnt
- E4BP4
- FOXO1a
- Meis-1
- Meis-1a
- Meis-1b
- POU2F1
- POU2F1a
- RFX1
- RORalpha1
Genomic Locations for KLHL8 Gene
Latest Assembly
- chr4:87,160,103-87,240,314
- (GRCh38/hg38)
- Size:
- 80,212 bases
- Orientation:
- Minus strand
Previous Assembly
- chr4:88,081,255-88,141,770
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 60,516 bases
- Orientation:
- Minus strand
- chr4:88,081,255-88,161,466
- (GRCh37/hg19 by Ensembl)
- Size:
- 80,212 bases
- Orientation:
- Minus strand
Genomic View for KLHL8 Gene
Genes around KLHL8 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4q22.1 by HGNC
- 4q22.1 by Entrez Gene
- 4q22.1 by Ensembl
KLHL8 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for KLHL8 Gene
Proteins for KLHL8 Gene
-
Protein details for KLHL8 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9P2G9-KLHL8_HUMAN
- Recommended name:
- Kelch-like protein 8
- Protein Accession:
- Q9P2G9
- Q53XA3
- Q6N018
Protein attributes for KLHL8 Gene
- Size:
- 620 amino acids
- Molecular mass:
- 68802 Da
- Quaternary structure:
-
- Component of the BCR(KLHL8) E3 ubiquitin ligase complex, at least composed of CUL3, KLHL8 and RBX1. Interacts with RAPSN.
- SequenceCaution:
-
- Sequence=BAA92616.2; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for KLHL8 Gene
Post-translational modifications for KLHL8 Gene
Other Protein References for KLHL8 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- Novus Biologicals Antibodies for KLHL8
- Invitrogen Antibodies for KLHL8 (AFLGC-KLHL8)
- antibodies-online: Show 4 available KLHL8 Antibodies ranked by validation data
-
Boster Bio Antibodies for KLHL8
-
Custom Antibody ServicesProSci Antibodies for KLHL8
Protein products for research
- Search Origene for MassSpec and Protein Over-expression Lysates for KLHL8
- Origene Custom Protein Services for KLHL8
-
Abcam proteins for KLHL8
Assay products for research
No data available for DME Specific Peptides for KLHL8 Gene
Domains & Families for KLHL8 Gene
Gene Families for KLHL8 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for KLHL8 Gene
- InterPro:
- Blocks:
-
- BTB/POZ domain
- BTB/Kelch-associated
- ProtoNet:
Suggested Antigen Peptide Sequences for KLHL8 Gene
- GenScript: Design optimal peptide antigens:
-
- Kelch-like protein 8 (KLHL8_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for KLHL8 Gene
Function for KLHL8 Gene
Molecular function for KLHL8 Gene
- UniProtKB/Swiss-Prot Function:
- Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN.
Phenotypes From GWAS Catalog for KLHL8 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IEA | -- |
Phenotypes for KLHL8 Gene
- MGI mutant phenotypes for KLHL8:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for KLHL8:
Animal Models for KLHL8 Gene
- MGI Knock Outs for KLHL8:
-
- Klhl8 Klhl8<tm1b(EUCOMM)Wtsi>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for KLHL8 - Starting at $85 >
- * KLHL8 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for KLHL8
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for KLHL8
-
Santa Cruz Biotechnology (SCBT) CRISPR for KLHL8
miRNA for KLHL8 Gene
- miRTarBase miRNAs that target KLHL8
-
- hsa-miR-215-5p (MIRT024647)
- hsa-miR-192-5p (MIRT026842)
- hsa-miR-615-3p (MIRT040093)
- hsa-miR-221-3p (MIRT046891)
- hsa-miR-498 (MIRT667698)
- hsa-miR-3976 (MIRT667699)
- hsa-miR-6856-5p (MIRT667700)
- hsa-miR-6758-5p (MIRT667701)
- hsa-miR-3121-3p (MIRT667702)
- hsa-miR-187-5p (MIRT738286)
- hsa-miR-222-3p (MIRT739084)
- hsa-miR-302a-3p (MIRT739631)
- hsa-miR-302b-3p (MIRT739641)
- hsa-miR-302c-3p (MIRT739650)
- hsa-miR-302d-3p (MIRT739661)
- hsa-miR-302e (MIRT739669)
- hsa-miR-325 (MIRT741237)
- hsa-miR-372-3p (MIRT742605)
- hsa-miR-373-3p (MIRT742618)
- hsa-miR-519a-3p (MIRT750111)
- hsa-miR-519b-3p (MIRT750129)
- hsa-miR-519c-3p (MIRT750147)
- hsa-miR-520a-3p (MIRT750181)
- hsa-miR-520b (MIRT750206)
- hsa-miR-520c-3p (MIRT750213)
- hsa-miR-520d-3p (MIRT750224)
- hsa-miR-520e (MIRT750237)
- hsa-miR-548v (MIRT750809)
- hsa-miR-628-3p (MIRT752631)
- hsa-miR-6823-5p (MIRT756924)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for KLHL8
- Browse OriGene Inhibitory RNA Products For KLHL8
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KLHL8
Clone products for research
- Applied Biological Materials (abm): Clones for KLHL8 - Starting at $45 >
- * KLHL8 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for KLHL8
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for KLHL8
Cell Lines for research
-
Horizon Cell Lines for KLHL8
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for KLHL8 Gene
Localization for KLHL8 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 3 |
| extracellular | 1 |
| endoplasmic reticulum | 1 |
- Nucleoplasm (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0031463 | Cul3-RING ubiquitin ligase complex | IDA | 19158078 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for KLHL8 Gene
Pathways & Interactions for KLHL8 Gene
UniProtKB/Swiss-Prot Q9P2G9-KLHL8_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for KLHL8 Gene
Selected Interacting proteins:
Q9P2G9-KLHL8_HUMAN
ENSP00000273963
for KLHL8 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for KLHL8
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006511 | ubiquitin-dependent protein catabolic process | IDA | 19158078 |
| GO:0016567 | protein ubiquitination | IDA,IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for KLHL8 Gene
Transcripts for KLHL8 Gene
mRNA/cDNA for KLHL8 Gene
- 4 REFSEQ mRNAs :
- 14 NCBI additional mRNA sequence :
- 8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000273963 5631 nts (view in UCSC)
- ENST00000425278 4049 nts (view in UCSC)
- ENST00000498875 5175 nts (view in UCSC)
- ENST00000504029 593 nts (view in UCSC)
- ENST00000505388 606 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for KLHL8 - Starting at $85 >
- * KLHL8 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for KLHL8
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for KLHL8
-
Santa Cruz Biotechnology (SCBT) CRISPR for KLHL8
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for KLHL8
- Browse OriGene Inhibitory RNA Products For KLHL8
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KLHL8
Clone products for research
- Applied Biological Materials (abm): Clones for KLHL8 - Starting at $45 >
- * KLHL8 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for KLHL8
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for KLHL8
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||
| SP2: | - | - |
Relevant External Links for KLHL8 Gene
- GeneLoc Exon Structure for
- KLHL8
Expression for KLHL8 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for KLHL8 Gene
This gene is overexpressed in Muscle - Skeletal (x4.0).
This gene is overexpressed in Fetal heart (52.6) and Heart (15.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for KLHL8 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for KLHL8
SOURCE GeneReport for Unigene cluster for KLHL8 Gene:
Hs.106601Evidence on tissue expression from TISSUES for KLHL8 Gene
- Nervous system(4.3)
Primer products for research
-
OriGene qPCR primer pairs for KLHL8
-
OriGene qPCR primer pairs and template standards for KLHL8
Gene Expression Assays for research
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KLHL8 Gene
Orthologs for KLHL8 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | KLHL8 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | KLHL8 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | KLHL8 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | KLHL8 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | KLHL8 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Klhl8 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Klhl8 30 |
|
||
| Chicken (Gallus gallus) |
Aves | KLHL8 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | KLHL8 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | klhl8 30 |
|
||
| Str.2178 30 |
|
||||
| Zebrafish (Danio rerio) |
Actinopterygii | klhl8 30 31 |
|
OneToOne | |
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.3234 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | kel-8 30 31 |
|
OneToOne | |
| W02G9.2 32 |
|
|
- Species where no ortholog for KLHL8 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for KLHL8 Gene
- ENSEMBL:
- Gene Tree for KLHL8 (if available)
- TreeFam:
- Gene Tree for KLHL8 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for KLHL8: view image
Paralogs for KLHL8 Gene
Paralogs for KLHL8 Gene
- KLHL20 5
- KLHL1 5
- KLHL17 5
- KLHL5 5
- KLHL4 5
- KLHL3 5
- KLHL2 5
- KLHL12 5
- KLHL18 5
- KLHL28 5
- KEAP1 5
- IPP 5
- KLHL29 5
- KLHL10 5
- KLHL7 5
- KLHL36 5
- IVNS1ABP 5
- KLHL9 5
- KLHL13 5
- KLHL23 5
- KLHL15 5
- KLHL31 5
- KLHL26 5
- KLHL6 5
- KLHL24 5
- KLHL21 5
- KLHL32 5
- KLHL35 5
- KBTBD3 5
- KLHL30 5
- KBTBD2 5
- KLHL40 5
- KLHL38 5
- KBTBD8 5
- KBTBD12 5
- KLHL41 5
- KBTBD7 5
- KLHL14 5
- GAN 5
- KLHL22 5
- KBTBD6 5
- KLHL34 5
- CCIN 5
- KBTBD11 5
- KLHL42 5
- KLHL33 5
- KLHDC8A 5
- KBTBD13 5
- KLHDC8B 5
- KLHDC7B 5
- KLHDC7A 5
- GRIK1-AS2 5
- BACH2 5
- BTBD18 5
- ENSG00000277971 5
(21) SIMAP similar genes for KLHL8 Gene using alignment to 3 proteins:
- KLHL8_HUMAN
- D6RGH5_HUMAN
- Q49A95_HUMAN
Variants for KLHL8 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for KLHL8 Gene
| SNP ID | Clinical significance and condition | Chr 04 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs17854114 | - |
p.Pro520Arg |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv5335n100 | CNV | gain | 25217958 |
| esv2727936 | CNV | deletion | 23290073 |
| esv2727937 | CNV | deletion | 23290073 |
| esv3601265 | CNV | loss | 21293372 |
| esv3601267 | CNV | loss | 21293372 |
| nsv1114549 | CNV | deletion | 24896259 |
| nsv822636 | CNV | gain | 20364138 |
| nsv966294 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
21.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.89;
18.58% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for KLHL8 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- KLHL8
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KLHL8 Gene
Disorders for KLHL8 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| verrucous papilloma |
|
|
| enamel caries |
|
|
| holoprosencephaly 3 |
|
|
Search KLHL8 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for KLHL8
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for KLHL8 Gene
Publications for KLHL8 Gene
- Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study. (PMID: 20800603) Flachsbart F … Nebel A (Mutation research 2010) 3 41
- Control of rapsyn stability by the CUL-3-containing E3 ligase complex. (PMID: 19158078) Nam S … Lee J (The Journal of biological chemistry 2009) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PMID: 12168954) Nakajima D … Nagase T (DNA research : an international journal for rapid publication of reports on genes and genomes 2002) 3 4
- Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2000) 3 4
ExternalLinks
Products for KLHL8 Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for KLHL8
- Origene Custom Protein Services for KLHL8
- Origene shrna, sirna, and RNAi products in human, mouse, rat for KLHL8
- Browse OriGene Inhibitory RNA Products For KLHL8
- OriGene qPCR primer pairs for KLHL8
- OriGene qPCR primer pairs and template standards for KLHL8
- OriGene CRISPR knockouts for KLHL8
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For KLHL8
- Sino Biological Human cDNA Clone for KLHL8
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for KLHL8
- Novus Biologicals proteins and lysates for KLHL8
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam proteins for KLHL8
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for KLHL8 (AFLGC-KLHL8)
- VectorBuilder Custom and pre-made DNA vectors for KLHL8 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for KLHL8 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for KLHL8 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for KLHL8 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for KLHL8
- antibodies-online: Show 4 available KLHL8 Antibodies ranked by validation data
- antibodies-online: Search results for available KLHL8 related products ranked by validation data
- antibodies-online: Search results for available KLHL8 related products ranked by validation data
- Horizon Cell Lines for KLHL8
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for KLHL8
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for KLHL8
- Search GeneCopoeia for miRNA 3'UTR Target clone products for KLHL8
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KLHL8
- Boster Bio Antibodies for KLHL8
- Browse Boster Bio ELISA Kits
Sources for KLHL8 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB