Aliases for KLHL6 Gene
External Ids for KLHL6 Gene
Previous GeneCards Identifiers for KLHL6 Gene
This gene encodes a member of the kelch-like (KLHL) family of proteins, which is involved in B-lymphocyte antigen receptor signaling and germinal-center B-cell maturation. The encoded protein contains an N-terminal broad-complex, tramtrack and bric a brac (BTB) domain that facilitates protein binding and dimerization, a BTB and C-terminal kelch (BACK) domain, and six C-terminal kelch repeat domains. Naturally occurring mutations in this gene are associated with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]
GeneCards Summary for KLHL6 Gene
KLHL6 (Kelch Like Family Member 6) is a Protein Coding gene. An important paralog of this gene is KLHL24.
UniProtKB/Swiss-Prot for KLHL6 Gene
Involved in B-lymphocyte antigen receptor signaling and germinal center formation.