Aliases for KLHL42 Gene
External Ids for KLHL42 Gene
Previous HGNC Symbols for KLHL42 Gene
Previous GeneCards Identifiers for KLHL42 Gene
GeneCards Summary for KLHL42 Gene
KLHL42 (Kelch Like Family Member 42) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and Innate Immune System. Gene Ontology (GO) annotations related to this gene include ubiquitin-protein transferase activity. An important paralog of this gene is KBTBD13.
UniProtKB/Swiss-Prot Summary for KLHL42 Gene
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis.