Aliases for KLF9 Gene
External Ids for KLF9 Gene
Previous HGNC Symbols for KLF9 Gene
Previous GeneCards Identifiers for KLF9 Gene
The protein encoded by this gene is a transcription factor that binds to GC box elements located in the promoter. Binding of the encoded protein to a single GC box inhibits mRNA expression while binding to tandemly repeated GC box elements activates transcription. [provided by RefSeq, Jul 2008]
GeneCards Summary for KLF9 Gene
KLF9 (Kruppel Like Factor 9) is a Protein Coding gene. Diseases associated with KLF9 include Endometrial Cancer and Otosclerosis. Among its related pathways are Diurnally Regulated Genes with Circadian Orthologs and Circadian rythm related genes. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity. An important paralog of this gene is KLF13.
UniProtKB/Swiss-Prot Summary for KLF9 Gene
Transcription factor that binds to GC box promoter elements. Selectively activates mRNA synthesis from genes containing tandem repeats of GC boxes but represses genes with a single GC box. Acts as an epidermal circadian transcription factor regulating keratinocyte proliferation (PubMed:22711835).