KLF18 Gene (Protein Coding)

Kruppel Like Factor 18

GC01M044138
GIFtS:
10
See more...

Aliases for KLF18 Gene

Aliases for KLF18 Gene

  • Kruppel Like Factor 18 2 3 5
  • Kruppel-Like Factor 18 3 4
  • KLF Pseudogene 3
  • KLF18 5

External Ids for KLF18 Gene

Summaries for KLF18 Gene

GeneCards Summary for KLF18 Gene

KLF18 (Kruppel Like Factor 18) is a Protein Coding gene. An important paralog of this gene is KLF5.

Additional gene information for KLF18 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for KLF18 Gene

Genomics for KLF18 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for KLF18 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around KLF18 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for KLF18

Genomic Locations for KLF18 Gene

Genomic Locations for KLF18 Gene
chr1:44,137,821-44,141,631
(GRCh38/hg38)
Size:
3,811 bases
Orientation:
Minus strand

Genomic View for KLF18 Gene

Genes around KLF18 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KLF18 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KLF18 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for KLF18 Gene

Proteins for KLF18 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for KLF18 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0A0U1RQI7-KLF18_HUMAN
    Recommended name:
    Kruppel-like factor 18
    Protein Accession:
    A0A0U1RQI7

    Protein attributes for KLF18 Gene

    Size:
    1052 amino acids
    Molecular mass:
    112602 Da
    Quaternary structure:
    No Data Available

neXtProt entry for KLF18 Gene

Post-translational modifications for KLF18 Gene

No Post-translational modifications

Other Protein References for KLF18 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KLF18 Gene

Domains & Families for KLF18 Gene

Gene Families for KLF18 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for KLF18 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

A0A0U1RQI7

UniProtKB/Swiss-Prot:

KLF18_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with KLF18: view

No data available for Suggested Antigen Peptide Sequences for KLF18 Gene

Function for KLF18 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for KLF18 Gene

Gene Ontology (GO) - Molecular Function for KLF18 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000976 transcription regulatory region sequence-specific DNA binding IBA 21873635
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific IBA 21873635
GO:0003676 nucleic acid binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with KLF18: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for KLF18 Gene

Localization for KLF18 Gene

Subcellular locations from UniProtKB/Swiss-Prot for KLF18 Gene

Nucleus.

Gene Ontology (GO) - Cellular Components for KLF18 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA 21873635
genes like me logo Genes that share ontologies with KLF18: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for KLF18 Gene

Pathways & Interactions for KLF18 Gene

PathCards logo

SuperPathways for KLF18 Gene

No Data Available

Interacting Proteins for KLF18 Gene

Gene Ontology (GO) - Biological Process for KLF18 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006357 regulation of transcription by RNA polymerase II IBA --
GO:0045944 positive regulation of transcription by RNA polymerase II IBA 21873635
genes like me logo Genes that share ontologies with KLF18: view

No data available for Pathways by source and SIGNOR curated interactions for KLF18 Gene

Drugs & Compounds for KLF18 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for KLF18 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for KLF18 Gene

1 REFSEQ mRNAs :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for KLF18 Gene

No ASD Table

Relevant External Links for KLF18 Gene

GeneLoc Exon Structure for
KLF18

Expression for KLF18 Gene

Products:

  1. Primer
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for KLF18 Gene

Orthologs for KLF18 Gene

Evolution for KLF18 Gene

ENSEMBL:
Gene Tree for KLF18 (if available)
TreeFam:
Gene Tree for KLF18 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for KLF18: view image

No data available for Orthologs for KLF18 Gene

Paralogs for KLF18 Gene

Paralogs for KLF18 Gene

genes like me logo Genes that share paralogs with KLF18: view

Variants for KLF18 Gene

Additional dbSNP identifiers (rs#s) for KLF18 Gene

Additional Variant Information for KLF18 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KLF18

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for KLF18 Gene

Disorders for KLF18 Gene

Additional Disease Information for KLF18

ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform

No disorders were found for KLF18 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KLF18 Gene

Publications for KLF18 Gene

  1. A new family of predicted Krüppel-like factor genes and pseudogenes in placental mammals. (PMID: 24244731) Pei J … Grishin NV (PloS one 2013) 2 3
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4

ExternalLinks

View latest publications for KLF18 gene in Mastermind

Products for KLF18 Gene

Sources for KLF18 Gene