Aliases for KLC3 Gene
External Ids for KLC3 Gene
Previous GeneCards Identifiers for KLC3 Gene
This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria. [provided by RefSeq, Jul 2008]
GeneCards Summary for KLC3 Gene
KLC3 (Kinesin Light Chain 3) is a Protein Coding gene. Diseases associated with KLC3 include Spastic Paraplegia, Optic Atrophy, And Neuropathy. Among its related pathways are Golgi-to-ER retrograde transport and Signaling by Rho GTPases. Gene Ontology (GO) annotations related to this gene include microtubule binding and kinesin binding. An important paralog of this gene is KLC4.
UniProtKB/Swiss-Prot for KLC3 Gene
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.