Aliases for KIZ Gene
External Ids for KIZ Gene
Previous HGNC Symbols for KIZ Gene
Previous GeneCards Identifiers for KIZ Gene
The protein encoded by this gene localizes to centrosomes, strengthening and stabilizing the pericentriolar region prior to spindle formation. The encoded protein usually remains with the mother centrosome after centrosomal duplication. Sevral transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]
GeneCards Summary for KIZ Gene
KIZ (Kizuna Centrosomal Protein) is a Protein Coding gene. Diseases associated with KIZ include Retinitis Pigmentosa 69 and Retinitis Pigmentosa. Among its related pathways are PLK1 signaling events. Gene Ontology (GO) annotations related to this gene include protein kinase binding.
UniProtKB/Swiss-Prot Summary for KIZ Gene
Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.