External Ids for KIFC3 Gene
Previous GeneCards Identifiers for KIFC3 Gene
This gene encodes a member of the kinesin-14 family of microtubule motors. Members of this family play a role in the formation, maintenance and remodeling of the bipolar mitotic spindle. The protein encoded by this gene has cytoplasmic functions in the interphase cells. It may also be involved in the final stages of cytokinesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
GeneCards Summary for KIFC3 Gene
KIFC3 (Kinesin Family Member C3) is a Protein Coding gene. Diseases associated with KIFC3 include Cone-Rod Dystrophy 17 and Phosphoglycerate Dehydrogenase Deficiency. Among its related pathways are Chaperonin-mediated protein folding and Ectoderm Differentiation. Gene Ontology (GO) annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIFC2.
UniProtKB/Swiss-Prot Summary for KIFC3 Gene
Minus-end microtubule-dependent motor protein. Involved in apically targeted transport (By similarity). Required for zonula adherens maintenance.