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Aliases for KIF9 Gene

Aliases for KIF9 Gene

  • Kinesin Family Member 9 2 3 5
  • Kinesin-Like Protein KIF9 3
  • Kinesin Protein 9 3

External Ids for KIF9 Gene

Previous GeneCards Identifiers for KIF9 Gene

  • GC03M047058
  • GC03M046480
  • GC03M047230
  • GC03M047222
  • GC03M047244

Summaries for KIF9 Gene

GeneCards Summary for KIF9 Gene

KIF9 (Kinesin Family Member 9) is a Protein Coding gene. Among its related pathways are Golgi-to-ER retrograde transport and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include ATPase activity and microtubule binding. An important paralog of this gene is KIF6.

Additional gene information for KIF9 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIF9 Gene

Genomics for KIF9 Gene

GeneHancer (GH) Regulatory Elements for KIF9 Gene

Promoters and enhancers for KIF9 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J047280 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE 650.7 +0.1 108 4.7 CLOCK MLX YBX1 DMAP1 IRF4 YY1 SLC30A9 E2F8 ZNF143 ZNF263 KIF9 KLHL18 PTPN23 DHX30 ZNF589 SETD2 BOLA2P2 CCDC12 SCAP NBEAL2
GH03J047346 Enhancer 1.2 Ensembl ENCODE 11.4 -64.1 -64065 1 PKNOX1 SMAD1 ARNT YBX1 IRF4 TCF12 ZNF766 GATA2 E2F8 ZNF207 ENSG00000280173 NBEAL2 SETD2 CCDC12 SCAP BOLA2P2 ZNF589 KIF9 KLHL18 KIF9-AS1
GH03J047008 Enhancer 1.2 Ensembl ENCODE dbSUPER 10.7 +273.7 273717 2.3 HDGF PKNOX1 MAX EBF1 ZIC2 RAD21 ETS1 HIC1 ZFHX2 GLIS2 NRADDP NBEAL2 CCDC12 KIF9 KLHL18
GH03J047314 Enhancer 1.1 Ensembl ENCODE 11.2 -31.7 -31667 1.4 ATF1 SMAD1 ARNT TCF12 ZNF766 GATA2 ATF7 NCOA1 REST ZNF592 GC03P047316 KIF9 KLHL18 KIF9-AS1 SETD2 PTH1R MYL3 ZNF589
GH03J047140 Enhancer 1 Ensembl ENCODE 11 +142.0 141950 1.8 HDGF EGR1 ATF7 IKZF2 RUNX3 CEBPB NFIL3 SP1 PRDM6 IKZF1 NBEAL2 SETD2 KIF9-AS1 KIF9 KLHL18 PTPN23 MRPL57P3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around KIF9 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the KIF9 gene promoter:
  • c-Ets-1
  • Ik-3
  • AML1a
  • AREB6
  • ITF-2
  • Tal-1beta
  • Pax-5
  • LCR-F1
  • GATA-3
  • Evi-1

Genomic Locations for KIF9 Gene

Genomic Locations for KIF9 Gene
55,426 bases
Minus strand
55,426 bases
Minus strand

Genomic View for KIF9 Gene

Genes around KIF9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIF9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIF9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIF9 Gene

Proteins for KIF9 Gene

  • Protein details for KIF9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Kinesin-like protein KIF9
    Protein Accession:
    Secondary Accessions:
    • Q86Z28
    • Q9H8A4

    Protein attributes for KIF9 Gene

    790 amino acids
    Molecular mass:
    89986 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB14713.1; Type=Miscellaneous discrepancy; Note=Dubious isoform. Probable cloning artifact lacking polyadenylation evidence.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for KIF9 Gene

    Alternative splice isoforms for KIF9 Gene


neXtProt entry for KIF9 Gene

Post-translational modifications for KIF9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

  • Abcam antibodies for KIF9
  • Boster Bio Antibodies for KIF9
  • Santa Cruz Biotechnology (SCBT) Antibodies for KIF9

No data available for DME Specific Peptides for KIF9 Gene

Domains & Families for KIF9 Gene

Gene Families for KIF9 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Suggested Antigen Peptide Sequences for KIF9 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
  • Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
genes like me logo Genes that share domains with KIF9: view

Function for KIF9 Gene

Phenotypes From GWAS Catalog for KIF9 Gene

Gene Ontology (GO) - Molecular Function for KIF9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003774 motor activity IEA --
GO:0003777 microtubule motor activity IBA --
GO:0005515 protein binding IPI 21119006
GO:0005524 ATP binding IEA --
GO:0008017 microtubule binding IEA --
genes like me logo Genes that share ontologies with KIF9: view
genes like me logo Genes that share phenotypes with KIF9: view

Animal Model Products

  • Taconic Biosciences Mouse Models for KIF9

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for KIF9 Gene

Localization for KIF9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for KIF9 Gene

Cytoplasm, cytoskeleton.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KIF9 gene
Compartment Confidence
cytoskeleton 5
nucleus 3
cytosol 3

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoli (2)
  • Nucleus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for KIF9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002102 podosome IDA 21119006
GO:0005737 cytoplasm IEA --
GO:0005856 cytoskeleton IEA --
GO:0005871 kinesin complex IBA --
GO:0005874 microtubule IDA,IEA 21119006
genes like me logo Genes that share ontologies with KIF9: view

Pathways & Interactions for KIF9 Gene

genes like me logo Genes that share pathways with KIF9: view

Gene Ontology (GO) - Biological Process for KIF9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007018 microtubule-based movement IBA --
GO:0022617 extracellular matrix disassembly IMP 21119006
GO:0071801 regulation of podosome assembly IMP 21119006
GO:1903008 organelle disassembly IMP 21119006
genes like me logo Genes that share ontologies with KIF9: view

No data available for SIGNOR curated interactions for KIF9 Gene

Drugs & Compounds for KIF9 Gene

No Compound Related Data Available

Transcripts for KIF9 Gene

Unigene Clusters for KIF9 Gene

Kinesin family member 9:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIF9 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d · 5e · 5f ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^
SP1: - - - - - - - - - -
SP2: - - - - - - - - - -
SP3: - - - - - - - - - -
SP4: - - - - -
SP5: - -
SP6: -
SP7: - - - -
SP8: - - - -
SP9: - -
SP11: - - -

ExUns: 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25
SP1: -
SP2: - -

Relevant External Links for KIF9 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for KIF9 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for KIF9 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for KIF9 Gene

This gene is overexpressed in Testis (x9.3).

Protein differential expression in normal tissues from HIPED for KIF9 Gene

This gene is overexpressed in Urine (20.4), Frontal cortex (16.0), Platelet (15.9), Testis (9.4), and Blymphocyte (7.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for KIF9 Gene

Protein tissue co-expression partners for KIF9 Gene

NURSA nuclear receptor signaling pathways regulating expression of KIF9 Gene:


SOURCE GeneReport for Unigene cluster for KIF9 Gene:


Evidence on tissue expression from TISSUES for KIF9 Gene

  • Thyroid gland(4.2)
genes like me logo Genes that share expression patterns with KIF9: view

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KIF9 Gene

Orthologs for KIF9 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIF9 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia KIF9 34 33
  • 96.86 (n)
(Canis familiaris)
Mammalia KIF9 34 33
  • 90.49 (n)
(Bos Taurus)
Mammalia KIF9 34 33
  • 90.07 (n)
(Rattus norvegicus)
Mammalia Kif9 33
  • 88.06 (n)
(Mus musculus)
Mammalia Kif9 16 34 33
  • 87.05 (n)
(Monodelphis domestica)
Mammalia KIF9 34
  • 75 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 35 (a)
-- 34
  • 14 (a)
(Gallus gallus)
Aves KIF9 34 33
  • 64.91 (n)
(Anolis carolinensis)
Reptilia KIF9 34
  • 58 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100492300 33
  • 66.3 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.15806 33
(Danio rerio)
Actinopterygii LOC553438 33
  • 56.76 (n)
KIF9 34
  • 40 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 48 (a)
Species where no ortholog for KIF9 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIF9 Gene

Gene Tree for KIF9 (if available)
Gene Tree for KIF9 (if available)
Evolutionary constrained regions (ECRs) for KIF9: view image

Paralogs for KIF9 Gene

Paralogs for KIF9 Gene

genes like me logo Genes that share paralogs with KIF9: view

Variants for KIF9 Gene

Sequence variations from dbSNP and Humsavar for KIF9 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1000016139 -- 47,255,546(-) G/A intron_variant
rs1000098136 -- 47,264,491(-) C/T genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000106868 -- 47,260,376(-) C/T intron_variant
rs1000114736 -- 47,238,650(-) T/C intron_variant
rs1000258294 -- 47,258,211(-) C/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for KIF9 Gene

Variant ID Type Subtype PubMed ID
nsv1007714 CNV gain 25217958
nsv428417 CNV loss 18775914

Variation tolerance for KIF9 Gene

Residual Variation Intolerance Score: 81.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.00; 49.83% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for KIF9 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIF9 Gene

Disorders for KIF9 Gene

Additional Disease Information for KIF9

No disorders were found for KIF9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIF9 Gene

Publications for KIF9 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. The Ras-like GTPase Gem is involved in cell shape remodelling and interacts with the novel kinesin-like protein KIF9. (PMID: 11483511) Piddini E … Dotti CG (The EMBO journal 2001) 2 3 58
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  5. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. (PMID: 26871637) Yang X … Vidal M (Cell 2016) 3 58

Products for KIF9 Gene

Sources for KIF9 Gene

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