Aliases for KIF3B Gene
External Ids for KIF3B Gene
Previous GeneCards Identifiers for KIF3B Gene
The protein encoded by this gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily. [provided by RefSeq, Jul 2008]
GeneCards Summary for KIF3B Gene
KIF3B (Kinesin Family Member 3B) is a Protein Coding gene. Diseases associated with KIF3B include Myasthenic Syndrome, Congenital, 16 and Polycystic Kidney Disease 2 With Or Without Polycystic Liver Disease. Among its related pathways are Organelle biogenesis and maintenance and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF3C.
UniProtKB/Swiss-Prot Summary for KIF3B Gene
Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity).