Aliases for KIF3A Gene
External Ids for KIF3A Gene
Previous GeneCards Identifiers for KIF3A Gene
GeneCards Summary for KIF3A Gene
KIF3A (Kinesin Family Member 3A) is a Protein Coding gene. Diseases associated with KIF3A include Polycystic Kidney Disease 2 With Or Without Polycystic Liver Disease and Usher Syndrome, Type I. Among its related pathways are Signaling by GPCR and Golgi-to-ER retrograde transport. Gene Ontology (GO) annotations related to this gene include ATPase activity and microtubule binding. An important paralog of this gene is KIF3B.
UniProtKB/Swiss-Prot Summary for KIF3A Gene
Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole.