Free for academic non-profit institutions. Other users need a Commercial license

Aliases for KIF28P Gene

Aliases for KIF28P Gene

  • Kinesin Family Member 28, Pseudogene 2 3 5
  • Kinesin-Like Protein Family Member 6-Like 3
  • Kinesin-Like Protein 6 4
  • KLP-6 3
  • KLP6 4

External Ids for KIF28P Gene

Previous GeneCards Identifiers for KIF28P Gene

  • GC01M246936

Summaries for KIF28P Gene

GeneCards Summary for KIF28P Gene

KIF28P (Kinesin Family Member 28, Pseudogene) is a Pseudogene. Among its related pathways are Golgi-to-ER retrograde transport and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include microtubule binding and microtubule motor activity.

UniProtKB/Swiss-Prot for KIF28P Gene

  • Microtubule-dependent motor protein required for mitochondrion morhology and transport of mitochondria in neuronal cells.

Additional gene information for KIF28P Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIF28P Gene

Genomics for KIF28P Gene

GeneHancer (GH) Regulatory Elements for KIF28P Gene

Promoters and enhancers for KIF28P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J246837 Enhancer 0.6 ENCODE 650.7 +1.7 1657 0.2 PAF1 ZNF639 CBFA2T3 TCF12 MEF2D FOSL1 POLR2A MYNN BCLAF1 SUPT5H KIF28P AHCTF1 ENSG00000252011
GH01J246723 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE 7.4 +113.2 113155 5.8 HDGF FOXA2 ARNT ARID4B SIN3A ZNF2 YY1 SLC30A9 ZNF143 REST SCCPDH ZNF669 ZNF496 ZNF670-ZNF695 AHCTF1 ENSG00000260855 KIF28P PIR55920
GH01J246959 Enhancer 1.2 FANTOM5 Ensembl ENCODE 10.6 -120.6 -120584 1.2 BCOR HDAC1 CTCF MEIS2 ATF1 TEAD4 BACH1 CEBPG RAD21 ZNF316 AHCTF1 ZNF669 ZNF670-ZNF695 ZNF124 KIF28P LINC01341 ZNF496 NLRP3 ZNF695
GH01J246703 Enhancer 1.1 Ensembl ENCODE 6.8 +133.7 133657 4.7 ELF3 FOXA2 NFIB NEUROD1 RAD21 RFX5 YY1 EGR1 RCOR1 FOS SCCPDH KIF28P ENSG00000235021
GH01J246676 Enhancer 0.6 ENCODE 7.2 +162.0 161951 1.8 PKNOX1 FEZF1 ZNF843 PRDM6 ZNF366 ZNF629 WT1 SP7 TCF7L2 LINC01341 KIF28P ENSG00000260698 ENSG00000225300 LOC102724382 GC01M246668
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around KIF28P on UCSC Golden Path with GeneCards custom track

Genomic Locations for KIF28P Gene

Genomic Locations for KIF28P Gene
chr1:246,770,907-246,839,611
(GRCh38/hg38)
Size:
68,705 bases
Orientation:
Minus strand
chr1:246,935,139-246,993,361
(GRCh37/hg19)
Size:
58,223 bases
Orientation:
Minus strand

Genomic View for KIF28P Gene

Genes around KIF28P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIF28P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIF28P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIF28P Gene

Proteins for KIF28P Gene

  • Protein details for KIF28P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B7ZC32-KIF28_HUMAN
    Recommended name:
    Kinesin-like protein KIF28P
    Protein Accession:
    B7ZC32

    Protein attributes for KIF28P Gene

    Size:
    967 amino acids
    Molecular mass:
    108254 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAX12164.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for KIF28P Gene

Post-translational modifications for KIF28P Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for KIF28P Gene

Domains & Families for KIF28P Gene

Gene Families for KIF28P Gene

Graphical View of Domain Structure for InterPro Entry

B7ZC32

UniProtKB/Swiss-Prot:

KIF28_HUMAN :
  • Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Family:
  • Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
genes like me logo Genes that share domains with KIF28P: view

No data available for Suggested Antigen Peptide Sequences for KIF28P Gene

Function for KIF28P Gene

Molecular function for KIF28P Gene

UniProtKB/Swiss-Prot Function:
Microtubule-dependent motor protein required for mitochondrion morhology and transport of mitochondria in neuronal cells.

Gene Ontology (GO) - Molecular Function for KIF28P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003777 microtubule motor activity IBA --
GO:0005524 ATP binding IEA --
GO:0008017 microtubule binding IEA --
GO:0016887 ATPase activity IBA --
genes like me logo Genes that share ontologies with KIF28P: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for KIF28P Gene

Localization for KIF28P Gene

Subcellular locations from UniProtKB/Swiss-Prot for KIF28P Gene

Mitochondrion membrane; Peripheral membrane protein.

Gene Ontology (GO) - Cellular Components for KIF28P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular ISS --
GO:0005871 kinesin complex IBA --
GO:0005874 microtubule IBA --
GO:0031966 mitochondrial membrane ISS --
genes like me logo Genes that share ontologies with KIF28P: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for KIF28P Gene

Pathways & Interactions for KIF28P Gene

genes like me logo Genes that share pathways with KIF28P: view

Interacting Proteins for KIF28P Gene

Gene Ontology (GO) - Biological Process for KIF28P Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007005 mitochondrion organization ISS --
GO:0007018 microtubule-based movement IBA --
GO:0072384 organelle transport along microtubule ISS --
genes like me logo Genes that share ontologies with KIF28P: view

No data available for SIGNOR curated interactions for KIF28P Gene

Drugs & Compounds for KIF28P Gene

No Compound Related Data Available

Transcripts for KIF28P Gene

mRNA/cDNA for KIF28P Gene

(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for KIF28P Gene

No ASD Table

Relevant External Links for KIF28P Gene

GeneLoc Exon Structure for
KIF28P
ECgene alternative splicing isoforms for
KIF28P

Expression for KIF28P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for KIF28P Gene

Protein differential expression in normal tissues from HIPED for KIF28P Gene

This gene is overexpressed in Heart (67.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for KIF28P Gene



Protein tissue co-expression partners for KIF28P Gene

NURSA nuclear receptor signaling pathways regulating expression of KIF28P Gene:

KIF28P
genes like me logo Genes that share expression patterns with KIF28P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for KIF28P Gene

Orthologs for KIF28P Gene

This gene was present in the common ancestor of animals.

Orthologs for KIF28P Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC100610366 33
  • 97.73 (n)
cow
(Bos Taurus)
Mammalia LOC101906868 33
  • 84.02 (n)
dog
(Canis familiaris)
Mammalia LOC102153289 33
  • 81.62 (n)
mouse
(Mus musculus)
Mammalia Gm1305 33
  • 77.88 (n)
Kif28 16
rat
(Rattus norvegicus)
Mammalia RGD1559696 33
  • 77.32 (n)
chicken
(Gallus gallus)
Aves LOC101748750 33
  • 68.72 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101732886 33
  • 65.11 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC100537112 33
  • 59.67 (n)
worm
(Caenorhabditis elegans)
Secernentea klp-6 33
  • 48.22 (n)
Species where no ortholog for KIF28P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for KIF28P Gene

ENSEMBL:
Gene Tree for KIF28P (if available)
TreeFam:
Gene Tree for KIF28P (if available)

Paralogs for KIF28P Gene

(11) SIMAP similar genes for KIF28P Gene using alignment to 1 proteins:

  • KIF28_HUMAN
genes like me logo Genes that share paralogs with KIF28P: view

No data available for Paralogs for KIF28P Gene

Variants for KIF28P Gene

Additional Variant Information for KIF28P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KIF28P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for KIF28P Gene

Disorders for KIF28P Gene

No disorders were found for KIF28P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for KIF28P Gene

Publications for KIF28P Gene

  1. Analysis of the kinesin superfamily: insights into structure and function. (PMID: 16084724) Miki H … Hirokawa N (Trends in cell biology 2005) 2 3 58
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4 58
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for KIF28P Gene

Sources for KIF28P Gene

Content
Loading form....