Aliases for KIF23 Gene
External Ids for KIF23 Gene
Previous HGNC Symbols for KIF23 Gene
Previous GeneCards Identifiers for KIF23 Gene
The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]
GeneCards Summary for KIF23 Gene
KIF23 (Kinesin Family Member 23) is a Protein Coding gene. Diseases associated with KIF23 include Anemia, Congenital Dyserythropoietic, Type Iii and Congenital Dyserythropoietic Anemia. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Mitotic Telophase/Cytokinesis. Gene Ontology (GO) annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF20A.
UniProtKB/Swiss-Prot Summary for KIF23 Gene
Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro.