Aliases for KIF20A Gene
External Ids for KIF20A Gene
Previous HGNC Symbols for KIF20A Gene
Previous GeneCards Identifiers for KIF20A Gene
GeneCards Summary for KIF20A Gene
KIF20A (Kinesin Family Member 20A) is a Protein Coding gene. Diseases associated with KIF20A include Familial Isolated Restrictive Cardiomyopathy and Charcot-Marie-Tooth Disease, Type 4C. Among its related pathways are Class I MHC mediated antigen processing and presentation and Golgi-to-ER retrograde transport. Gene Ontology (GO) annotations related to this gene include protein kinase binding and ATPase activity. An important paralog of this gene is KIF23.
UniProtKB/Swiss-Prot Summary for KIF20A Gene
Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.