Aliases for KIF1C Gene
External Ids for KIF1C Gene
Previous HGNC Symbols for KIF1C Gene
Previous GeneCards Identifiers for KIF1C Gene
The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. Mutations in this gene are a cause of spastic ataxia 2, autosomal recessive. [provided by RefSeq, May 2014]
GeneCards Summary for KIF1C Gene
KIF1C (Kinesin Family Member 1C) is a Protein Coding gene. Diseases associated with KIF1C include Spastic Ataxia 2, Autosomal Recessive and Alacrima, Achalasia, And Mental Retardation Syndrome. Among its related pathways are Golgi-to-ER retrograde transport and Reelin Pathway (Cajal-Retzius cells). Gene Ontology (GO) annotations related to this gene include microtubule binding. An important paralog of this gene is KIF1A.
UniProtKB/Swiss-Prot Summary for KIF1C Gene
Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility.