Aliases for KIF1B Gene
External Ids for KIF1B Gene
Previous HGNC Symbols for KIF1B Gene
Previous GeneCards Identifiers for KIF1B Gene
This gene encodes a motor protein that transports mitochondria and synaptic vesicle precursors. Mutations in this gene cause Charcot-Marie-Tooth disease, type 2A1. [provided by RefSeq, Jul 2008]
GeneCards Summary for KIF1B Gene
KIF1B (Kinesin Family Member 1B) is a Protein Coding gene. Diseases associated with KIF1B include Charcot-Marie-Tooth Disease, Axonal, Type 2A1 and Neuroblastoma. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Golgi-to-ER retrograde transport. Gene Ontology (GO) annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF1A.
UniProtKB/Swiss-Prot for KIF1B Gene
Motor for anterograde transport of mitochondria. Has a microtubule plus end-directed motility. Isoform 2 is required for induction of neuronal apoptosis.