Aliases for KIF16B Gene
External Ids for KIF16B Gene
Previous HGNC Symbols for KIF16B Gene
Previous GeneCards Identifiers for KIF16B Gene
The protein encoded by this gene is a kinesin-like protein that may be involved in intracellular trafficking. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
GeneCards Summary for KIF16B Gene
KIF16B (Kinesin Family Member 16B) is a Protein Coding gene. Diseases associated with KIF16B include Small Intestine Neuroendocrine Neoplasm. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Golgi-to-ER retrograde transport. Gene Ontology (GO) annotations related to this gene include ATPase activity and Rab GTPase binding. An important paralog of this gene is KIF1A.
UniProtKB/Swiss-Prot Summary for KIF16B Gene
Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development.