Aliases for KIAA2012 Gene

Aliases for KIAA2012 Gene

  • KIAA2012 2 3
  • Uncharacterized Protein KIAA2012 3 4

External Ids for KIAA2012 Gene

Summaries for KIAA2012 Gene

GeneCards Summary for KIAA2012 Gene

KIAA2012 (KIAA2012) is a Protein Coding gene.

Additional gene information for KIAA2012 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for KIAA2012 Gene

Genomics for KIAA2012 Gene

GeneHancer (GH) Regulatory Elements for KIAA2012 Gene

Promoters and enhancers for KIAA2012 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around KIAA2012 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for KIAA2012

Genomic Locations for KIAA2012 Gene

Genomic Locations for KIAA2012 Gene
chr2:202,073,253-202,205,195
(GRCh38/hg38)
Size:
131,943 bases
Orientation:
Plus strand
chr2:202,937,978-203,062,585
(GRCh37/hg19)
Size:
124,608 bases
Orientation:
Plus strand

Genomic View for KIAA2012 Gene

Genes around KIAA2012 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA2012 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA2012 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA2012 Gene

Proteins for KIAA2012 Gene

  • Protein details for KIAA2012 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q0VF49-K2012_HUMAN
    Recommended name:
    Uncharacterized protein KIAA2012
    Protein Accession:
    Q0VF49
    Secondary Accessions:
    • Q8IVF9

    Protein attributes for KIAA2012 Gene

    Size:
    1180 amino acids
    Molecular mass:
    135305 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC23108.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};

    Alternative splice isoforms for KIAA2012 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KIAA2012 Gene

Post-translational modifications for KIAA2012 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KIAA2012 Gene

No data available for DME Specific Peptides for KIAA2012 Gene

Domains & Families for KIAA2012 Gene

Gene Families for KIAA2012 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for KIAA2012 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with KIAA2012: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for KIAA2012 Gene

Function for KIAA2012 Gene

Phenotypes From GWAS Catalog for KIAA2012 Gene

genes like me logo Genes that share phenotypes with KIAA2012: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for KIAA2012 Gene

Localization for KIAA2012 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KIAA2012 gene
Compartment Confidence
nucleus 2
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for KIAA2012 Gene

Pathways & Interactions for KIAA2012 Gene

PathCards logo

SuperPathways for KIAA2012 Gene

No Data Available

Interacting Proteins for KIAA2012 Gene

;

Gene Ontology (GO) - Biological Process for KIAA2012 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KIAA2012 Gene

Drugs & Compounds for KIAA2012 Gene

No Compound Related Data Available

Transcripts for KIAA2012 Gene

mRNA/cDNA for KIAA2012 Gene

3 REFSEQ mRNAs :
6 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA2012 Gene

No ASD Table

Relevant External Links for KIAA2012 Gene

GeneLoc Exon Structure for
KIAA2012

Expression for KIAA2012 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for KIAA2012 Gene

Protein differential expression in normal tissues from HIPED for KIAA2012 Gene

This gene is overexpressed in Plasma (68.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for KIAA2012 Gene



Protein tissue co-expression partners for KIAA2012 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for KIAA2012

genes like me logo Genes that share expression patterns with KIAA2012: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for KIAA2012 Gene

Orthologs for KIAA2012 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA2012 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC747458 30
  • 98.91 (n)
-- 31
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC102155450 30
  • 83.67 (n)
cow
(Bos Taurus)
Mammalia LOC614993 30
  • 82.13 (n)
-- 31
  • 35 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1562029 30
  • 76.08 (n)
mouse
(Mus musculus)
Mammalia Gm973 17 31 30
  • 75.52 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 47 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 29 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 31
  • 39 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101733381 30
  • 50.03 (n)
zebrafish
(Danio rerio)
Actinopterygii CR407547.1 31
  • 8 (a)
OneToOne
Species where no ortholog for KIAA2012 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA2012 Gene

ENSEMBL:
Gene Tree for KIAA2012 (if available)
TreeFam:
Gene Tree for KIAA2012 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for KIAA2012: view image

Paralogs for KIAA2012 Gene

(1) SIMAP similar genes for KIAA2012 Gene using alignment to 1 proteins:

  • K2012_HUMAN
genes like me logo Genes that share paralogs with KIAA2012: view

No data available for Paralogs for KIAA2012 Gene

Variants for KIAA2012 Gene

Additional dbSNP identifiers (rs#s) for KIAA2012 Gene

Structural Variations from Database of Genomic Variants (DGV) for KIAA2012 Gene

Variant ID Type Subtype PubMed ID
esv2559685 CNV deletion 19546169
esv3593991 CNV loss 21293372
nsv1072483 CNV deletion 25765185
nsv1121726 CNV deletion 24896259
nsv1142974 CNV tandem duplication 24896259
nsv1148588 CNV deletion 26484159
nsv3112 CNV insertion 18451855
nsv472061 CNV novel sequence insertion 20440878
nsv525156 CNV loss 19592680
nsv834512 CNV loss 17160897
nsv955019 CNV deletion 24416366

Additional Variant Information for KIAA2012 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KIAA2012

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for KIAA2012 Gene

Disorders for KIAA2012 Gene

Additional Disease Information for KIAA2012

No disorders were found for KIAA2012 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA2012 Gene

Publications for KIAA2012 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54
  2. Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. (PMID: 18951430) Anney RJ … Gill M (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008) 3 54
  3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 4 54
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 54
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 54

Products for KIAA2012 Gene

Sources for KIAA2012 Gene