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Aliases for KIAA1958 Gene

Aliases for KIAA1958 Gene

  • KIAA1958 2 3
  • Uncharacterized Protein KIAA1958 3

External Ids for KIAA1958 Gene

Previous GeneCards Identifiers for KIAA1958 Gene

  • GC09P106134
  • GC09P106981
  • GC09P108706
  • GC09P110629
  • GC09P112328
  • GC09P114288
  • GC09P115249
  • GC09P084933

Summaries for KIAA1958 Gene

GeneCards Summary for KIAA1958 Gene

KIAA1958 (KIAA1958) is a Protein Coding gene.

Additional gene information for KIAA1958 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA1958 Gene

Genomics for KIAA1958 Gene

GeneHancer (GH) Regulatory Elements for KIAA1958 Gene

Promoters and enhancers for KIAA1958 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J112485 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 650.7 +0.4 391 2.6 HDGF PKNOX1 CLOCK ARID4B SIN3A DMAP1 ZNF2 SLC30A9 POLR2B CBX5 KIAA1958 HSDL2 C9orf147
GH09J112793 Enhancer 0.9 Ensembl ENCODE 11.2 +306.5 306498 0.3 CTCF SAP130 ARID4B MAX IRF4 RBPJ RAD21 CTBP1 GATA3 VEZF1 ENSG00000226609 SNX30 INIP KIAA1958 C9orf147 PIR49803
GH09J112447 Enhancer 0.8 Ensembl ENCODE 12.1 -39.2 -39246 0.4 MEIS2 PKNOX1 DPF2 ZEB2 MITF ZNF316 FOXK2 VEZF1 ZFP91 NFE2 KIAA1958 C9orf147 HSDL2 INIP PIR60820
GH09J111937 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 5.3 -548.6 -548556 2.6 HDGF PKNOX1 SMAD1 RB1 STAT5A BMI1 BATF IRF4 YY1 EGR1 RNU6-710P RNU6-1013P GNG10 KIAA1958 C9orf84 PTBP3 SUSD1 DNAJC25 HSDL2 MIR4668
GH09J112788 Enhancer 0.6 Ensembl ENCODE 11.2 +302.9 302854 1.8 MITF CTCF IKZF1 ENSG00000226609 SNX30 INIP C9orf147 KIAA1958 SLC46A2 PIR49803
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around KIAA1958 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the KIAA1958 gene promoter:
  • Pax-6
  • HNF-3beta
  • STAT3
  • AML1a
  • FOXD1
  • C/EBPalpha
  • GATA-6
  • SEF-1 (1)
  • RREB-1

Genomic Locations for KIAA1958 Gene

Genomic Locations for KIAA1958 Gene
182,551 bases
Plus strand
182,551 bases
Plus strand

Genomic View for KIAA1958 Gene

Genes around KIAA1958 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA1958 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA1958 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA1958 Gene

Proteins for KIAA1958 Gene

  • Protein details for KIAA1958 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein KIAA1958
    Protein Accession:
    Secondary Accessions:
    • B7ZKW6
    • Q2M336
    • Q5T252
    • Q8TF43
    • Q96N02

    Protein attributes for KIAA1958 Gene

    716 amino acids
    Molecular mass:
    79212 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB71114.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for KIAA1958 Gene


neXtProt entry for KIAA1958 Gene

Post-translational modifications for KIAA1958 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KIAA1958 Gene

Antibody Products

  • Boster Bio Antibodies for KIAA1958

No data available for DME Specific Peptides for KIAA1958 Gene

Domains & Families for KIAA1958 Gene

Gene Families for KIAA1958 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for KIAA1958 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA1958: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for KIAA1958 Gene

Function for KIAA1958 Gene

Phenotypes From GWAS Catalog for KIAA1958 Gene

Gene Ontology (GO) - Molecular Function for KIAA1958 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA --
GO:0003677 DNA binding IBA --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with KIAA1958: view

Phenotypes for KIAA1958 Gene

genes like me logo Genes that share phenotypes with KIAA1958: view

Animal Model Products

CRISPR Products

miRNA for KIAA1958 Gene

miRTarBase miRNAs that target KIAA1958

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KIAA1958

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA1958 Gene

Localization for KIAA1958 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KIAA1958 gene
Compartment Confidence
nucleus 4
plasma membrane 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for KIAA1958 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IBA --
GO:0005737 cytoplasm IBA --
genes like me logo Genes that share ontologies with KIAA1958: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for KIAA1958 Gene

Pathways & Interactions for KIAA1958 Gene

SuperPathways for KIAA1958 Gene

No Data Available

Gene Ontology (GO) - Biological Process for KIAA1958 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006357 regulation of transcription by RNA polymerase II IEA --
GO:0007010 cytoskeleton organization IBA --
GO:0022604 regulation of cell morphogenesis IBA --
genes like me logo Genes that share ontologies with KIAA1958: view

No data available for Pathways by source and SIGNOR curated interactions for KIAA1958 Gene

Drugs & Compounds for KIAA1958 Gene

No Compound Related Data Available

Transcripts for KIAA1958 Gene

mRNA/cDNA for KIAA1958 Gene

Unigene Clusters for KIAA1958 Gene

Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KIAA1958

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1958 Gene

No ASD Table

Relevant External Links for KIAA1958 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for KIAA1958 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for KIAA1958 Gene

Protein differential expression in normal tissues from HIPED for KIAA1958 Gene

This gene is overexpressed in Plasma (52.7), Lymph node (9.5), and Testis (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for KIAA1958 Gene

Protein tissue co-expression partners for KIAA1958 Gene

NURSA nuclear receptor signaling pathways regulating expression of KIAA1958 Gene:


SOURCE GeneReport for Unigene cluster for KIAA1958 Gene:


Evidence on tissue expression from TISSUES for KIAA1958 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with KIAA1958: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KIAA1958 Gene

Orthologs for KIAA1958 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA1958 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia KIAA1958 34 33
  • 99.82 (n)
(Bos Taurus)
Mammalia KIAA1958 34
  • 96 (a)
(Canis familiaris)
Mammalia KIAA1958 34
  • 94 (a)
(Monodelphis domestica)
Mammalia KIAA1958 34
  • 87 (a)
(Ornithorhynchus anatinus)
Mammalia KIAA1958 34
  • 86 (a)
(Mus musculus)
Mammalia E130308A19Rik 34
  • 61 (a)
(Gallus gallus)
Aves KIAA1958 34
  • 47 (a)
(Anolis carolinensis)
Reptilia KIAA1958 34
  • 49 (a)
(Danio rerio)
Actinopterygii si:ch211-126i22.5 34
  • 24 (a)
Species where no ortholog for KIAA1958 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA1958 Gene

Gene Tree for KIAA1958 (if available)
Gene Tree for KIAA1958 (if available)
Evolutionary constrained regions (ECRs) for KIAA1958: view image

Paralogs for KIAA1958 Gene

No data available for Paralogs for KIAA1958 Gene

Variants for KIAA1958 Gene

Sequence variations from dbSNP and Humsavar for KIAA1958 Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000012735 -- 112,522,986(+) G/A genic_upstream_transcript_variant, intron_variant
rs1000040225 -- 112,556,695(+) T/C intron_variant
rs1000044836 -- 112,637,713(+) A/G genic_downstream_transcript_variant, intron_variant
rs1000092182 -- 112,556,468(+) T/C intron_variant
rs1000114037 -- 112,653,673(+) G/A genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for KIAA1958 Gene

Variant ID Type Subtype PubMed ID
dgv1231n67 CNV gain 20364138
dgv262e55 CNV gain 17911159
dgv4127n106 CNV deletion 24896259
dgv7701n100 CNV gain 25217958
esv1050816 CNV deletion 17803354
esv1174496 CNV insertion 17803354
esv1674209 CNV insertion 17803354
esv1981326 CNV deletion 18987734
esv2333544 CNV deletion 18987734
esv2500783 CNV deletion 19546169
esv2559748 CNV insertion 19546169
esv2663019 CNV deletion 23128226
esv2667240 CNV deletion 23128226
esv2738947 CNV deletion 23290073
esv2738948 CNV deletion 23290073
esv2738949 CNV deletion 23290073
esv2741005 CNV deletion 23290073
esv2759710 CNV gain 17122850
esv2761275 CNV gain 21179565
esv3305 CNV loss 18987735
esv3339732 CNV insertion 20981092
esv3621516 CNV loss 21293372
esv3621517 CNV gain 21293372
esv3621518 CNV gain 21293372
nsv1051625 CNV loss 25217958
nsv1110053 CNV deletion 24896259
nsv1135296 CNV deletion 24896259
nsv1147695 CNV deletion 26484159
nsv416371 CNV deletion 16902084
nsv442163 CNV gain 18776908
nsv466488 CNV loss 19166990
nsv471317 CNV gain 18288195
nsv510204 OTHER sequence alteration 20534489
nsv511430 CNV loss 21212237
nsv515121 CNV gain 21397061
nsv515899 CNV gain+loss 19592680
nsv615197 CNV loss 21841781
nsv615198 CNV gain 21841781
nsv6670 CNV insertion 18451855
nsv6671 CNV deletion 18451855
nsv956109 CNV deletion 24416366
nsv972801 CNV duplication 23825009

Variation tolerance for KIAA1958 Gene

Residual Variation Intolerance Score: 10.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.78; 33.57% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for KIAA1958 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA1958 Gene

Disorders for KIAA1958 Gene

Additional Disease Information for KIAA1958

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for KIAA1958 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA1958 Gene

Publications for KIAA1958 Gene

  1. Crypton transposons: identification of new diverse families and ancient domestication events. (PMID: 22011512) Kojima KK … Jurka J (Mobile DNA 2011) 2 3 58
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  4. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 3 4 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58

Products for KIAA1958 Gene

Sources for KIAA1958 Gene

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