Aliases for KIAA1671 Gene

Aliases for KIAA1671 Gene

  • KIAA1671 2 3
  • Uncharacterized Protein KIAA1671 3 4
  • CTA-221G9.5 3

External Ids for KIAA1671 Gene

Previous GeneCards Identifiers for KIAA1671 Gene

  • GC22P022162
  • GC22P023761
  • GC22P023748
  • GC22P023751
  • GC22P023734
  • GC22P025421
  • GC22P008371
  • GC22P025348

Summaries for KIAA1671 Gene

GeneCards Summary for KIAA1671 Gene

KIAA1671 (KIAA1671) is a Protein Coding gene. An important paralog of this gene is TNKS1BP1.

Additional gene information for KIAA1671 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for KIAA1671 Gene

Genomics for KIAA1671 Gene

GeneHancer (GH) Regulatory Elements for KIAA1671 Gene

Promoters and enhancers for KIAA1671 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around KIAA1671 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the KIAA1671 gene promoter:
  • AREB6
  • ATF6
  • COUP
  • COUP-TF1
  • HNF-4alpha1
  • HNF-4alpha2
  • POU6F1 (c2)
  • STAT5B

Genomic Locations for KIAA1671 Gene

Genomic Locations for KIAA1671 Gene
244,747 bases
Plus strand
244,719 bases
Plus strand

Genomic View for KIAA1671 Gene

Genes around KIAA1671 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA1671 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA1671 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA1671 Gene

Proteins for KIAA1671 Gene

  • Protein details for KIAA1671 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein KIAA1671
    Protein Accession:
    Secondary Accessions:
    • B0QYF2
    • B7ZW08
    • Q5THZ5

    Protein attributes for KIAA1671 Gene

    1806 amino acids
    Molecular mass:
    196711 Da
    Quaternary structure:
    No Data Available
    • Antibodies against KIAA1671 are present in sera from patients with breast cancer who developed several autoantibodies.
    • Sequence=BAB33341.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for KIAA1671 Gene


neXtProt entry for KIAA1671 Gene

Post-translational modifications for KIAA1671 Gene

  • Ubiquitination at Lys1738
  • Modification sites at PhosphoSitePlus

Other Protein References for KIAA1671 Gene

No data available for DME Specific Peptides for KIAA1671 Gene

Domains & Families for KIAA1671 Gene

Gene Families for KIAA1671 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for KIAA1671 Gene


Suggested Antigen Peptide Sequences for KIAA1671 Gene

GenScript: Design optimal peptide antigens:
  • Novel protein (KIAA1671) (B0QYF1_HUMAN)
genes like me logo Genes that share domains with KIAA1671: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for KIAA1671 Gene

Function for KIAA1671 Gene

Phenotypes From GWAS Catalog for KIAA1671 Gene

genes like me logo Genes that share phenotypes with KIAA1671: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KIAA1671

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA1671 Gene

Localization for KIAA1671 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KIAA1671 gene
Compartment Confidence
cytoskeleton 2
nucleus 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA1671 Gene

Pathways & Interactions for KIAA1671 Gene

PathCards logo

SuperPathways for KIAA1671 Gene

No Data Available

Gene Ontology (GO) - Biological Process for KIAA1671 Gene


No data available for Pathways by source and SIGNOR curated interactions for KIAA1671 Gene

Drugs & Compounds for KIAA1671 Gene

No Compound Related Data Available

Transcripts for KIAA1671 Gene

mRNA/cDNA for KIAA1671 Gene

(1) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(6) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KIAA1671

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1671 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8

Relevant External Links for KIAA1671 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for KIAA1671 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for KIAA1671 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for KIAA1671 Gene

This gene is overexpressed in Retina (12.6), Gallbladder (12.2), Bone marrow mesenchymal stem cell (7.5), Peripheral blood mononuclear cells (6.7), Heart (6.4), and Pancreas (6.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for KIAA1671 Gene

NURSA nuclear receptor signaling pathways regulating expression of KIAA1671 Gene:


SOURCE GeneReport for Unigene cluster for KIAA1671 Gene:

genes like me logo Genes that share expression patterns with KIAA1671: view

No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for KIAA1671 Gene

Orthologs for KIAA1671 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA1671 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia KIAA1671 32
  • 98.87 (n)
-- 33
  • 98 (a)
(Canis familiaris)
Mammalia KIAA1671 32
  • 77.91 (n)
-- 33
  • 67 (a)
(Bos Taurus)
Mammalia KIAA1671 32
  • 73.28 (n)
-- 33
  • 61 (a)
(Mus musculus)
Mammalia 2900026A02Rik 33
  • 73 (a)
(Rattus norvegicus)
Mammalia RGD1306556 32
  • 68.07 (n)
(Ornithorhynchus anatinus)
Mammalia -- 33
  • 59 (a)
-- 33
  • 53 (a)
(Monodelphis domestica)
Mammalia -- 33
  • 39 (a)
(Gallus gallus)
Aves -- 33
  • 62 (a)
(Danio rerio)
Actinopterygii tnks1bp1 33
  • 29 (a)
si:ch73-138n13.1 33
  • 16 (a)
Species where no ortholog for KIAA1671 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA1671 Gene

Gene Tree for KIAA1671 (if available)
Gene Tree for KIAA1671 (if available)
Evolutionary constrained regions (ECRs) for KIAA1671: view image

Paralogs for KIAA1671 Gene

Paralogs for KIAA1671 Gene

genes like me logo Genes that share paralogs with KIAA1671: view

Variants for KIAA1671 Gene

Sequence variations from dbSNP and Humsavar for KIAA1671 Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs1000005018 -- 25,183,084(+) C/T intron_variant
rs1000008700 -- 25,064,931(+) T/A intron_variant
rs1000008993 -- 25,141,833(+) G/A intron_variant
rs1000013595 -- 25,183,264(+) C/T intron_variant
rs1000013949 -- 25,105,080(+) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for KIAA1671 Gene

Variant ID Type Subtype PubMed ID
dgv2447n106 CNV deletion 24896259
dgv2448n106 CNV deletion 24896259
dgv24e196 CNV duplication 17116639
dgv284e215 CNV deletion 23714750
dgv8069n54 CNV loss 21841781
dgv8070n54 CNV loss 21841781
esv2042759 CNV deletion 18987734
esv24048 CNV loss 19812545
esv2657573 CNV deletion 23128226
esv2724075 CNV deletion 23290073
esv2724076 CNV deletion 23290073
esv2724077 CNV deletion 23290073
esv2724078 CNV deletion 23290073
esv2758829 CNV gain+loss 17122850
esv3234493 CNV deletion 24192839
esv3305813 CNV mobile element insertion 20981092
esv3308687 CNV mobile element insertion 20981092
esv3343197 CNV insertion 20981092
esv33826 CNV loss 17666407
esv3396049 CNV insertion 20981092
esv3434566 CNV insertion 20981092
nsv1056865 CNV gain 25217958
nsv1057343 CNV gain 25217958
nsv1072631 CNV deletion 25765185
nsv1110863 OTHER inversion 24896259
nsv1151112 CNV deletion 26484159
nsv191604 CNV deletion 16902084
nsv3581 CNV insertion 18451855
nsv428388 CNV loss 18775914
nsv459684 CNV gain 19166990
nsv469581 CNV loss 16826518
nsv471188 CNV gain 18288195
nsv511634 CNV loss 21212237
nsv512651 CNV loss 21212237
nsv518136 CNV loss 19592680
nsv588747 CNV gain 21841781
nsv588755 CNV loss 21841781
nsv7350 OTHER inversion 18451855
nsv829131 CNV loss 20364138
nsv834161 CNV gain 17160897
nsv834162 CNV loss 17160897
nsv9885 CNV gain 18304495
nsv9886 CNV loss 18304495
nsv9887 CNV loss 18304495

Variation tolerance for KIAA1671 Gene

Gene Damage Index Score: 3.34; 53.66% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for KIAA1671 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA1671 Gene

Disorders for KIAA1671 Gene

Additional Disease Information for KIAA1671

No disorders were found for KIAA1671 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA1671 Gene

Publications for KIAA1671 Gene

  1. Autoantibodies to Annexin XI-A and Other Autoantigens in the Diagnosis of Breast Cancer. (PMID: 15289310) Fernández-Madrid F … Karvonen RL (Cancer research 2004) 2 3 4 56
  2. Proteomic Analysis Reveals a Novel Mutator S (MutS) Partner Involved in Mismatch Repair Pathway. (PMID: 27037360) Chen Z … Chen J (Molecular & cellular proteomics : MCP 2016) 2 3 56
  3. Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping. (PMID: 11258795) Hirosawa M … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2001) 3 4 56
  4. Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells. (PMID: 29509190) Giurato G … Tarallo R (Scientific data 2018) 3 56
  5. VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3 56

Products for KIAA1671 Gene

Sources for KIAA1671 Gene