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Aliases for KIAA1107 Gene

Aliases for KIAA1107 Gene

  • KIAA1107 2 3

External Ids for KIAA1107 Gene

Previous GeneCards Identifiers for KIAA1107 Gene

  • GC01M093020
  • GC01P091832
  • GC01P091972
  • GC01P092104
  • GC01P092344
  • GC01P092407
  • GC01P092632
  • GC01P090752

Summaries for KIAA1107 Gene

GeneCards Summary for KIAA1107 Gene

KIAA1107 (KIAA1107) is a Protein Coding gene. An important paralog of this gene is ENSG00000189195.

Additional gene information for KIAA1107 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA1107 Gene

Genomics for KIAA1107 Gene

GeneHancer (GH) Regulatory Elements for KIAA1107 Gene

Promoters and enhancers for KIAA1107 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I093078 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE 14.2 +913.5 913450 4.5 MLX ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 ZNF213 E2F8 ZNF416 MTF2 CCDC18-AS1 SNORA66 SNORD21 TRR-TCT1-1 GLMN RPAP2 RPL5 DR1 DNTTIP2
GH01I092831 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 10.9 +666.4 666444 4.2 CLOCK MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF213 E2F8 ZNF143 ZNF548 RPL5 GC01P092832 SNORA66 SNORD21 CCDC18-AS1 MTF2 MIG7 DR1 GLMN RPAP2
GH01I092079 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 6.8 -86.4 -86382 1.6 ATF1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 ZNF48 POLR2B GLIS2 BTBD8 ENSG00000189195 SNORA66 SNORD21 RPL5 KIAA1107 GAPDHP46 GC01P092039
GH01I092975 Enhancer 1.3 FANTOM5 ENCODE dbSUPER 10.4 +809.4 809424 5.3 HDGF PKNOX1 ZFP64 IRF4 TCF12 ZNF766 ZNF143 ATF7 RUNX3 JUNB RN7SL692P MTF2 CCDC18-AS1 SNORA66 TRR-TCT1-1 SNORD21 RPL5 EVI5 KIAA1107 MIG7
GH01I092095 Enhancer 0.5 Ensembl 15.9 -70.5 -70535 1.3 POLR2A CEBPG NFE2 PRDM1 KIAA1107 BTBD8 ENSG00000189195 GAPDHP46 GC01P092039
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around KIAA1107 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the KIAA1107 gene promoter:

Genomic Locations for KIAA1107 Gene

Genomic Locations for KIAA1107 Gene
chr1:92,166,985-92,184,723
(GRCh38/hg38)
Size:
17,739 bases
Orientation:
Plus strand
chr1:92,632,542-92,650,280
(GRCh37/hg19)

Genomic View for KIAA1107 Gene

Genes around KIAA1107 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA1107 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA1107 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA1107 Gene

Proteins for KIAA1107 Gene

  • Protein details for KIAA1107 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UPP5-K1107_HUMAN
    Recommended name:
    Uncharacterized protein KIAA1107
    Protein Accession:
    Q9UPP5
    Secondary Accessions:
    • O14767
    • Q8N3X7

    Protein attributes for KIAA1107 Gene

    Size:
    1409 amino acids
    Molecular mass:
    155681 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAC28132.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for KIAA1107 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KIAA1107 Gene

Post-translational modifications for KIAA1107 Gene

No Post-translational modifications

Other Protein References for KIAA1107 Gene

No data available for DME Specific Peptides for KIAA1107 Gene

Domains & Families for KIAA1107 Gene

Gene Families for KIAA1107 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for KIAA1107 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA1107: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for KIAA1107 Gene

Function for KIAA1107 Gene

Phenotypes From GWAS Catalog for KIAA1107 Gene

Phenotypes for KIAA1107 Gene

GenomeRNAi human phenotypes for KIAA1107:
genes like me logo Genes that share phenotypes with KIAA1107: view

Animal Model Products

CRISPR Products

miRNA for KIAA1107 Gene

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA1107 Gene

Localization for KIAA1107 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KIAA1107 gene
Compartment Confidence
nucleus 3
plasma membrane 2
cytosol 2
golgi apparatus 2
endosome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for KIAA1107 Gene

Pathways & Interactions for KIAA1107 Gene

SuperPathways for KIAA1107 Gene

No Data Available

Gene Ontology (GO) - Biological Process for KIAA1107 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KIAA1107 Gene

Drugs & Compounds for KIAA1107 Gene

No Compound Related Data Available

Transcripts for KIAA1107 Gene

mRNA/cDNA for KIAA1107 Gene

Unigene Clusters for KIAA1107 Gene

KIAA1107:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1107 Gene

No ASD Table

Relevant External Links for KIAA1107 Gene

GeneLoc Exon Structure for
KIAA1107
ECgene alternative splicing isoforms for
KIAA1107

Expression for KIAA1107 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for KIAA1107 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for KIAA1107 Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (x5.5), Brain - Cortex (x5.3), and Brain - Anterior cingulate cortex (BA24) (x4.1).

Protein differential expression in normal tissues from HIPED for KIAA1107 Gene

This gene is overexpressed in Monocytes (25.0), Plasma (23.3), and Frontal cortex (7.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for KIAA1107 Gene



Protein tissue co-expression partners for KIAA1107 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of KIAA1107 Gene:

KIAA1107

SOURCE GeneReport for Unigene cluster for KIAA1107 Gene:

Hs.21554

Evidence on tissue expression from TISSUES for KIAA1107 Gene

  • Nervous system(3.1)
genes like me logo Genes that share expression patterns with KIAA1107: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KIAA1107 Gene

Orthologs for KIAA1107 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA1107 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA1107 33 34
  • 99.34 (n)
dog
(Canis familiaris)
Mammalia KIAA1107 33 34
  • 88.72 (n)
rat
(Rattus norvegicus)
Mammalia LOC100364240 33
  • 73.18 (n)
mouse
(Mus musculus)
Mammalia A830010M20Rik 33 16 34
  • 73.09 (n)
cow
(Bos Taurus)
Mammalia BTBD8 34
  • 60 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA1107 34
  • 52 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KIAA1107 34
  • 45 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA1107 33 34
  • 67.39 (n)
lizard
(Anolis carolinensis)
Reptilia KIAA1107 34
  • 49 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa1107 33
  • 56.62 (n)
Str.17169 33
zebrafish
(Danio rerio)
Actinopterygii si:ch73-389b16.2 34
  • 26 (a)
OneToOne
Species where no ortholog for KIAA1107 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA1107 Gene

ENSEMBL:
Gene Tree for KIAA1107 (if available)
TreeFam:
Gene Tree for KIAA1107 (if available)

Paralogs for KIAA1107 Gene

Paralogs for KIAA1107 Gene

genes like me logo Genes that share paralogs with KIAA1107: view

Variants for KIAA1107 Gene

Sequence variations from dbSNP and Humsavar for KIAA1107 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1000236366 -- 92,169,589(+) A/C intron_variant
rs1000389803 -- 92,176,070(+) A/G intron_variant
rs1000539446 -- 92,169,855(+) A/G intron_variant
rs1000621722 -- 92,183,811(+) T/A intron_variant
rs1000817977 -- 92,169,347(+) T/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for KIAA1107 Gene

Variant ID Type Subtype PubMed ID
nsv546821 CNV gain 21841781
nsv1113149 CNV deletion 24896259
esv2714684 CNV deletion 23290073

Variation tolerance for KIAA1107 Gene

Gene Damage Index Score: 5.21; 69.89% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for KIAA1107 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KIAA1107

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA1107 Gene

Disorders for KIAA1107 Gene

Additional Disease Information for KIAA1107

No disorders were found for KIAA1107 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA1107 Gene

Publications for KIAA1107 Gene

  1. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10470851) Kikuno R … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1999) 2 3 4 58
  2. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 58
  3. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A … Wanker EE (Science signaling 2011) 3 58
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58

Products for KIAA1107 Gene

Sources for KIAA1107 Gene

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