Aliases for KIAA0895L Gene

Aliases for KIAA0895L Gene

  • KIAA0895 Like 2 3 5
  • Uncharacterized Protein KIAA0895-Like 3 4

External Ids for KIAA0895L Gene

Previous GeneCards Identifiers for KIAA0895L Gene

  • GC16M065774
  • GC16M065776
  • GC16M067209
  • GC16M053082

Summaries for KIAA0895L Gene

GeneCards Summary for KIAA0895L Gene

KIAA0895L (KIAA0895 Like) is a Protein Coding gene. An important paralog of this gene is KIAA0895.

Gene Wiki entry for KIAA0895L Gene

Additional gene information for KIAA0895L Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for KIAA0895L Gene

Genomics for KIAA0895L Gene

GeneHancer (GH) Regulatory Elements for KIAA0895L Gene

Promoters and enhancers for KIAA0895L Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around KIAA0895L on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for KIAA0895L

Top Transcription factor binding sites by QIAGEN in the KIAA0895L gene promoter:
  • AP-1
  • MyoD
  • NRSF form 1
  • NRSF form 2
  • p53

Genomic Locations for KIAA0895L Gene

Genomic Locations for KIAA0895L Gene
chr16:67,175,599-67,184,040
(GRCh38/hg38)
Size:
8,442 bases
Orientation:
Minus strand
chr16:67,209,505-67,217,943
(GRCh37/hg19)
Size:
8,439 bases
Orientation:
Minus strand

Genomic View for KIAA0895L Gene

Genes around KIAA0895L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA0895L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA0895L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA0895L Gene

Proteins for KIAA0895L Gene

  • Protein details for KIAA0895L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q68EN5-K895L_HUMAN
    Recommended name:
    Uncharacterized protein KIAA0895-like
    Protein Accession:
    Q68EN5
    Secondary Accessions:
    • A2VCS8
    • Q8N3H9
    • Q8NAQ5
    • Q96IE5

    Protein attributes for KIAA0895L Gene

    Size:
    471 amino acids
    Molecular mass:
    53446 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI28540.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAD38862.1; Type=Erroneous translation; Note=Erroneous translation incorporating non-existent frameshift.; Evidence={ECO:0000305};

    Alternative splice isoforms for KIAA0895L Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KIAA0895L Gene

Post-translational modifications for KIAA0895L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for KIAA0895L Gene

Domains & Families for KIAA0895L Gene

Gene Families for KIAA0895L Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for KIAA0895L Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with KIAA0895L: view

No data available for Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for KIAA0895L Gene

Function for KIAA0895L Gene

Phenotypes From GWAS Catalog for KIAA0895L Gene

genes like me logo Genes that share phenotypes with KIAA0895L: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA0895L Gene

Localization for KIAA0895L Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KIAA0895L gene
Compartment Confidence
nucleus 2
cytosol 2
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (2)
  • Vesicles (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA0895L Gene

Pathways & Interactions for KIAA0895L Gene

PathCards logo

SuperPathways for KIAA0895L Gene

No Data Available

Interacting Proteins for KIAA0895L Gene

STRING Interaction Network Preview (showing top 1 STRING interactants - click image to see details)
STRING Interaction Network
Selected Interacting proteins: ENSP00000290881 for KIAA0895L Gene via STRING

Symbol External ID(s) Details
ZBTB8B
;

Gene Ontology (GO) - Biological Process for KIAA0895L Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KIAA0895L Gene

Drugs & Compounds for KIAA0895L Gene

No Compound Related Data Available

Transcripts for KIAA0895L Gene

mRNA/cDNA for KIAA0895L Gene

8 REFSEQ mRNAs :
8 NCBI additional mRNA sequence :
12 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA0895L Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b · 8c
SP1: - - - -
SP2: - - -
SP3: -
SP4: - - - - - - - - - -
SP5:
SP6:
SP7: - -
SP8:

Relevant External Links for KIAA0895L Gene

GeneLoc Exon Structure for
KIAA0895L

Expression for KIAA0895L Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for KIAA0895L Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for KIAA0895L Gene

This gene is overexpressed in Monocytes (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for KIAA0895L Gene



Protein tissue co-expression partners for KIAA0895L Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for KIAA0895L

SOURCE GeneReport for Unigene cluster for KIAA0895L Gene:

Hs.651201

Evidence on tissue expression from TISSUES for KIAA0895L Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with KIAA0895L: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KIAA0895L Gene

Orthologs for KIAA0895L Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA0895L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA0895L 31 30
  • 99.22 (n)
OneToOne
dog
(Canis familiaris)
Mammalia KIAA0895L 31
  • 93 (a)
OneToOne
cow
(Bos Taurus)
Mammalia KIAA0895L 31 30
  • 89.6 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Kiaa0895l 30
  • 83.69 (n)
mouse
(Mus musculus)
Mammalia 4931428F04Rik 17 31 30
  • 83.44 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA0895L 31
  • 69 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KIAA0895L 31
  • 68 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA0895L 31 30
  • 79.31 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KIAA0895L 31
  • 79 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa0895l 30
  • 65.66 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC562097 30
  • 61.86 (n)
BX255936.1 31
  • 51 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 54 (a)
OneToMany
Species where no ortholog for KIAA0895L was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA0895L Gene

ENSEMBL:
Gene Tree for KIAA0895L (if available)
TreeFam:
Gene Tree for KIAA0895L (if available)
Aminode:
Evolutionary constrained regions (ECRs) for KIAA0895L: view image

Paralogs for KIAA0895L Gene

Paralogs for KIAA0895L Gene

(1) SIMAP similar genes for KIAA0895L Gene using alignment to 3 proteins:

  • K895L_HUMAN
  • H3BSG6_HUMAN
  • I3L230_HUMAN

Pseudogenes.org Pseudogenes for KIAA0895L Gene

genes like me logo Genes that share paralogs with KIAA0895L: view

Variants for KIAA0895L Gene

Additional dbSNP identifiers (rs#s) for KIAA0895L Gene

Structural Variations from Database of Genomic Variants (DGV) for KIAA0895L Gene

Variant ID Type Subtype PubMed ID
nsv1160429 CNV deletion 26073780
nsv457513 CNV loss 19166990
nsv471092 CNV gain 18288195
nsv522852 CNV gain 19592680
nsv524363 CNV loss 19592680
nsv524492 CNV loss 19592680
nsv572905 CNV loss 21841781
nsv827707 CNV loss 20364138
nsv952044 CNV deletion 24416366

Variation tolerance for KIAA0895L Gene

Residual Variation Intolerance Score: 49.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.32; 70.64% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for KIAA0895L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KIAA0895L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for KIAA0895L Gene

Disorders for KIAA0895L Gene

Additional Disease Information for KIAA0895L

No disorders were found for KIAA0895L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA0895L Gene

Publications for KIAA0895L Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54
  2. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. (PMID: 28611215) Fei T … Brown M (Proceedings of the National Academy of Sciences of the United States of America 2017) 3 54
  3. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 54
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 54
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 54

Products for KIAA0895L Gene

Sources for KIAA0895L Gene