Aliases for KIAA0753 Gene
External Ids for KIAA0753 Gene
Previous GeneCards Identifiers for KIAA0753 Gene
This gene encodes a subunit of a protein complex that regulates ciliogenesis and cilia maintenance. The encoded protein has also been shown to regulate centriolar duplication. Mutations in this gene cause an orofaciodigital syndrome and a form of Joubert syndrome in human patients. [provided by RefSeq, May 2017]
GeneCards Summary for KIAA0753 Gene
UniProtKB/Swiss-Prot Summary for KIAA0753 Gene
Involved in centriole duplication. Positively regulates CEP63 centrosomal localization. Required for WDR62 centrosomal localization and promotes the centrosomal localization of CDK2 (PubMed:24613305, PubMed:26297806).