Aliases for KHK Gene
External Ids for KHK Gene
Previous GeneCards Identifiers for KHK Gene
This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for KHK Gene
KHK (Ketohexokinase) is a Protein Coding gene. Diseases associated with KHK include Fructosuria, Essential and Nephronophthisis 3. Among its related pathways are Fructose metabolism and Fructose and mannose metabolism. Gene Ontology (GO) annotations related to this gene include fructokinase activity and ketohexokinase activity. An important paralog of this gene is RBKS.
UniProtKB/Swiss-Prot Summary for KHK Gene
Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate.