The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutatio... See more...

Aliases for KDSR Gene

Aliases for KDSR Gene

  • 3-Ketodihydrosphingosine Reductase 2 3 4 5
  • 3-Dehydrosphinganine Reductase 2 3 4
  • Short Chain Dehydrogenase/Reductase Family 35C Member 1 3 4
  • Follicular Lymphoma Variant Translocation 1 2 3
  • Follicular Variant Translocation Protein 1 3 4
  • KDS Reductase 3 4
  • SDR35C1 3 4
  • FVT-1 3 4
  • FVT1 3 4
  • Short Chain Dehydrogenase/Reductase Family 35C, Member 1 2
  • EC 1.1.1.102 4
  • EKVP4 3
  • DHSR 3

External Ids for KDSR Gene

Previous HGNC Symbols for KDSR Gene

  • FVT1

Previous GeneCards Identifiers for KDSR Gene

  • GC18M059145
  • GC18M060994
  • GC18M057693

Summaries for KDSR Gene

Entrez Gene Summary for KDSR Gene

  • The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy. [provided by RefSeq, Jul 2008]

GeneCards Summary for KDSR Gene

KDSR (3-Ketodihydrosphingosine Reductase) is a Protein Coding gene. Diseases associated with KDSR include Erythrokeratodermia Variabilis Et Progressiva 4 and Erythrokeratodermia Variabilis Et Progressiva 1. Among its related pathways are Sphingolipid metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and 3-dehydrosphinganine reductase activity. An important paralog of this gene is RDH13.

UniProtKB/Swiss-Prot Summary for KDSR Gene

  • Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).

Gene Wiki entry for KDSR Gene

Additional gene information for KDSR Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for KDSR Gene

Genomics for KDSR Gene

GeneHancer (GH) Regulatory Elements for KDSR Gene

Promoters and enhancers for KDSR Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH18J063365 Promoter/Enhancer 2.3 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas 521.8 +0.3 273 4 RXRA EP300 ZBTB40 ZNF217 ZSCAN5C TCF12 POLR2G SP1 NCOR1 PHF8 KDSR ENSG00000267390 lnc-VPS4B-2 ZCCHC2 lnc-BCL2-3
GH18J063311 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 7.2 +50.9 50882 10.6 RXRA ZBTB40 SIN3A NRF1 USF1 SP1 CTCF EP300 ZIC2 POLR2A BCL2 KDSR lnc-KDSR-2
GH18J063197 Enhancer 1.3 FANTOM5 ENCODE dbSUPER 10.7 +168.3 168347 3.6 EP300 SIN3A RBAK ZBTB5 ATF2 ZNF148 ZNF266 KLF9 WT1 ZBTB17 HSALNG0122033 ENSG00000267560 ENSG00000266900 KDSR ZCCHC2 BCL2 VPS4B PHLPP1 ENSG00000283125
GH18J063334 Enhancer 1 Ensembl ENCODE dbSUPER 9.6 +30.6 30563 3.5 JUND FOS EP300 TEAD1 FOXA2 MAFF SAP130 MAFK CEBPB JUN lnc-BCL2-3 KDSR lnc-VPS4B-2
GH18J063092 Enhancer 0.8 Ensembl dbSUPER 10.7 +275.1 275072 0.4 ZBTB10 KLF9 ZSCAN18 SRF ZFHX2 ZNF621 BCL11B ZNF18 ZNF785 ZNF791 ENSG00000267560 BCL2 KDSR LOC105372161 MG828560 piR-61945-238 lnc-BCL2-2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around KDSR on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for KDSR

Top Transcription factor binding sites by QIAGEN in the KDSR gene promoter:
  • FOXL1
  • GATA-3
  • HNF-4alpha1
  • HNF-4alpha2
  • STAT1beta
  • STAT2
  • STAT3
  • STAT4
  • STAT5A
  • STAT5B

Genomic Locations for KDSR Gene

Genomic Locations for KDSR Gene
chr18:63,327,726-63,367,273
(GRCh38/hg38)
Size:
39,548 bases
Orientation:
Minus strand
chr18:60,994,959-61,034,743
(GRCh37/hg19)
Size:
39,785 bases
Orientation:
Minus strand

Genomic View for KDSR Gene

Genes around KDSR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KDSR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KDSR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KDSR Gene

Proteins for KDSR Gene

  • Protein details for KDSR Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q06136-KDSR_HUMAN
    Recommended name:
    3-ketodihydrosphingosine reductase
    Protein Accession:
    Q06136
    Secondary Accessions:
    • B2R5Y1
    • B4DMX0

    Protein attributes for KDSR Gene

    Size:
    332 amino acids
    Molecular mass:
    36187 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for KDSR Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KDSR Gene

Post-translational modifications for KDSR Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for KDSR Gene

Domains & Families for KDSR Gene

Gene Families for KDSR Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Disease related genes
  • Enzymes
  • Potential drug targets
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for KDSR Gene

Blocks:
  • Short-chain dehydrogenase/reductase SDR
  • Glucose/ribitol dehydrogenase family signature
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for KDSR Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ57536, moderately similar to 3-ketodihydrosphingosine reductase (EC 1.1.1.102) (B4DMX0_HUMAN)
  • Follicular variant translocation protein 1 (KDSR_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q06136

UniProtKB/Swiss-Prot:

KDSR_HUMAN :
  • Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Family:
  • Belongs to the short-chain dehydrogenases/reductases (SDR) family.
genes like me logo Genes that share domains with KDSR: view

Function for KDSR Gene

Molecular function for KDSR Gene

UniProtKB/Swiss-Prot Function:
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=NADP(+) + sphinganine = 3-oxosphinganine + H(+) + NADPH; Xref=Rhea:RHEA:22640, ChEBI:CHEBI:15378, ChEBI:CHEBI:57783, ChEBI:CHEBI:57817, ChEBI:CHEBI:58299, ChEBI:CHEBI:58349; EC=1.1.1.102; Evidence=. ;.

Enzyme Numbers (IUBMB) for KDSR Gene

Phenotypes From GWAS Catalog for KDSR Gene

Gene Ontology (GO) - Molecular Function for KDSR Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016491 oxidoreductase activity IEA --
GO:0047560 3-dehydrosphinganine reductase activity TAS --
genes like me logo Genes that share ontologies with KDSR: view
genes like me logo Genes that share phenotypes with KDSR: view

Human Phenotype Ontology for KDSR Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Model Products

  • Taconic Biosciences Mouse Models for KDSR

CRISPR Products

miRNA for KDSR Gene

miRTarBase miRNAs that target KDSR

Clone Products

No data available for Animal Models , Transcription Factor Targets and HOMER Transcription for KDSR Gene

Localization for KDSR Gene

Subcellular locations from UniProtKB/Swiss-Prot for KDSR Gene

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KDSR gene
Compartment Confidence
endoplasmic reticulum 5
extracellular 4
plasma membrane 2
cytoskeleton 1
mitochondrion 1
nucleus 1
endosome 1
cytosol 1
lysosome 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for KDSR Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space TAS 8417785
GO:0005783 endoplasmic reticulum IDA 15364918
GO:0005789 endoplasmic reticulum membrane TAS --
GO:0016020 membrane HDA,IEA 19946888
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with KDSR: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for KDSR Gene

Pathways & Interactions for KDSR Gene

genes like me logo Genes that share pathways with KDSR: view

Pathways by source for KDSR Gene

UniProtKB/Swiss-Prot Q06136-KDSR_HUMAN

  • Pathway: Lipid metabolism; sphingolipid metabolism.

Interacting Proteins for KDSR Gene

;

Gene Ontology (GO) - Biological Process for KDSR Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006629 lipid metabolic process IEA --
GO:0006665 sphingolipid metabolic process IEA --
GO:0006666 3-keto-sphinganine metabolic process IBA,IDA 15364918
GO:0030148 sphingolipid biosynthetic process TAS --
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with KDSR: view

No data available for SIGNOR curated interactions for KDSR Gene

Drugs & Compounds for KDSR Gene

(2) Drugs for KDSR Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
NADP Experimental Pharma 0
sphinganine Pharma 0

(3) Additional Compounds for KDSR Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
3-Dehydrosphinganine
  • 3-dehydro-D-Sphinganine
  • 3-Ketodihydrosphingosine
  • 3-Ketosphinganine
  • (2S)-2-amino-1-Hydroxyoctadecan-3-one
  • 1-Hydroxy-2-amino-3-oxo-octadecane
16105-69-4
Hydrogen Ion
  • H+
  • H(+)
  • Hydrogen cation
  • Hydron
  • Proton
nadph
  • 2'-(Dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-D-ribofuranosylnicotinamide
  • 2'-(Dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide
  • Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-D-ribofuranosyl-3-pyridinecarboxamide
  • Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosyl-3-pyridinecarboxamide
  • b-NADPH
53-57-6
genes like me logo Genes that share compounds with KDSR: view

Transcripts for KDSR Gene

mRNA/cDNA for KDSR Gene

1 REFSEQ mRNAs :
10 NCBI additional mRNA sequence :
13 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for KDSR Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b · 12c
SP1: - - - -
SP2: - - - -
SP3:
SP4: -
SP5: -
SP6:

Relevant External Links for KDSR Gene

GeneLoc Exon Structure for
KDSR

Expression for KDSR Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for KDSR Gene

Protein differential expression in normal tissues from HIPED for KDSR Gene

This gene is overexpressed in Retina (6.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for KDSR Gene



Protein tissue co-expression partners for KDSR Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for KDSR

SOURCE GeneReport for Unigene cluster for KDSR Gene:

Hs.74050

mRNA Expression by UniProt/SwissProt for KDSR Gene:

Q06136-KDSR_HUMAN
Tissue specificity: Expressed in all tissues examined. Highest expression in placenta. High expression in lung, kidney, stomach and small intestine, low expression in heart, spleen and skeletal muscle. Weakly expressed in normal hematopoietic tissues. Higher expression in some T-cell malignancies and PHA-stimulated lymphocytes.

Evidence on tissue expression from TISSUES for KDSR Gene

  • Nervous system(4.9)
  • Heart(4.3)
genes like me logo Genes that share expression patterns with KDSR: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for KDSR Gene

Orthologs for KDSR Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for KDSR Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KDSR 31 30
  • 100 (n)
OneToOne
dog
(Canis familiaris)
Mammalia KDSR 31 30
  • 89.75 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KDSR 31
  • 89 (a)
OneToOne
cow
(Bos Taurus)
Mammalia KDSR 31 30
  • 88.65 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Kdsr 17 31 30
  • 88.19 (n)
rat
(Rattus norvegicus)
Mammalia Kdsr 30
  • 87.45 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia KDSR 31
  • 85 (a)
OneToOne
chicken
(Gallus gallus)
Aves KDSR 31
  • 85 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KDSR 31
  • 71 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kdsr 30
  • 75.34 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.16086 30
zebrafish
(Danio rerio)
Actinopterygii kdsr 31 30
  • 73.57 (n)
OneToOne
zgc55947 30
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003984 30
  • 50.11 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG10425 31 30
  • 49.05 (n)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea Y37E11AM.3 31
  • 37 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes TSC10 33
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G19200 30
  • 45.61 (n)
rice
(Oryza sativa)
Liliopsida Os02g0701900 30
  • 48.77 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 52 (a)
OneToOne
Species where no ortholog for KDSR was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for KDSR Gene

ENSEMBL:
Gene Tree for KDSR (if available)
TreeFam:
Gene Tree for KDSR (if available)
Aminode:
Evolutionary constrained regions (ECRs) for KDSR: view image

Paralogs for KDSR Gene

Paralogs for KDSR Gene

(1) SIMAP similar genes for KDSR Gene using alignment to 4 proteins:

  • KDSR_HUMAN
  • B4DMX0_HUMAN
  • K7EQS7_HUMAN
  • K7ERC8_HUMAN
genes like me logo Genes that share paralogs with KDSR: view

Variants for KDSR Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for KDSR Gene

SNP ID Clinical significance and condition Chr 18 pos Variation AA Info Type
753931 Benign: not provided 63,338,803(-) G/A SYNONYMOUS_VARIANT
rs1114167450 Pathogenic: Erythrokeratodermia variabilis et progressiva 4 63,362,810(-) CCTT/C INFRAME_INDEL
rs1114167451 Pathogenic: Erythrokeratodermia variabilis et progressiva 4 63,355,565(-) T/G SPLICE_ACCEPTOR_VARIANT
rs1114167452 Pathogenic: Erythrokeratodermia variabilis et progressiva 4. Erythrokeratodermia variabilis et progressiva 4 (EKVP4) [MIM:617526] 63,350,940(-) T/Ap.Tyr186Phe MISSENSE_VARIANT
rs752611378 Pathogenic: Erythrokeratodermia variabilis et progressiva 4 63,335,257(-) C/T SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for KDSR Gene

Structural Variations from Database of Genomic Variants (DGV) for KDSR Gene

Variant ID Type Subtype PubMed ID
esv1455992 CNV insertion 17803354
esv2657702 CNV deletion 23128226
esv2671992 CNV deletion 23128226
esv2717201 CNV deletion 23290073
esv3305878 CNV mobile element insertion 20981092
esv3325049 CNV insertion 20981092
esv3642768 CNV loss 21293372
esv3642769 CNV gain 21293372
esv3642770 CNV loss 21293372
nsv1066552 CNV gain 25217958
nsv577096 CNV loss 21841781

Variation tolerance for KDSR Gene

Residual Variation Intolerance Score: 15% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.56; 12.15% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for KDSR Gene

Human Gene Mutation Database (HGMD)
KDSR
SNPedia medical, phenotypic, and genealogical associations of SNPs for
KDSR

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KDSR Gene

Disorders for KDSR Gene

MalaCards: The human disease database

(8) MalaCards diseases for KDSR Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, and GeneCards

- elite association - COSMIC cancer census association via MalaCards
Search KDSR in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

KDSR_HUMAN
  • Note=A chromosomal aberration involving KDSR is a cause of follicular lymphoma; also known as type II chronic lymphatic leukemia. Translocation t(2;18)(p11;q21) with a Ig J kappa chain region (PubMed:8417785). {ECO:0000269 PubMed:8417785}.
  • Erythrokeratodermia variabilis et progressiva 4 (EKVP4) [MIM:617526]: A form of erythrokeratodermia variabilis et progressiva, a genodermatosis characterized by the coexistence of two independent skin lesions: transient erythema and hyperkeratosis that is usually localized but occasionally occurs in its generalized form. Clinical presentation varies significantly within a family and from one family to another. Palmoplantar keratoderma is present in around 50% of cases. {ECO:0000269 PubMed:28575652}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for KDSR

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with KDSR: view

No data available for Genatlas for KDSR Gene

Publications for KDSR Gene

  1. FVT-1 is a mammalian 3-ketodihydrosphingosine reductase with an active site that faces the cytosolic side of the endoplasmic reticulum membrane. (PMID: 15328338) Kihara A … Igarashi Y (The Journal of biological chemistry 2004) 2 3 4 23 54
  2. FVT-1, a novel human transcription unit affected by variant translocation t(2;18)(p11;q21) of follicular lymphoma. (PMID: 8417785) Rimokh R … Magaud JP (Blood 1993) 2 3 4 23 54
  3. A missense mutation in the 3-ketodihydrosphingosine reductase FVT1 as candidate causal mutation for bovine spinal muscular atrophy. (PMID: 17420465) Krebs S … Förster M (Proceedings of the National Academy of Sciences of the United States of America 2007) 2 3 23 54
  4. Mutations in KDSR Cause Recessive Progressive Symmetric Erythrokeratoderma. (PMID: 28575652) Boyden LM … Choate KA (American journal of human genetics 2017) 3 4 54
  5. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood HD … Lan Q (Occupational and environmental medicine 2009) 3 41 54

Products for KDSR Gene

Sources for KDSR Gene