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The protein encoded by this gene is a lysine-specific demethylase that specifically demethylates di- or tri-methylated lysine 27 of histone H3 (H3K27me2 or H3K27me3). H3K27 trimethylation is a repressive epigenetic mark controlling chromatin organization and gene silencing. This protein can also demethylate non-histone proteins such as retinoblastoma protein. Through its demeth... See more...
Aliases for KDM6B Gene
Aliases for KDM6B Gene
External Ids for KDM6B Gene
- HGNC: 29012
- Entrez Gene: 23135
- Ensembl: ENSG00000132510
- OMIM: 611577
- UniProtKB: O15054
Previous HGNC Symbols for KDM6B Gene
- JMJD3
Previous GeneCards Identifiers for KDM6B Gene
- GC17P007686
Summaries for KDM6B Gene
-
The protein encoded by this gene is a lysine-specific demethylase that specifically demethylates di- or tri-methylated lysine 27 of histone H3 (H3K27me2 or H3K27me3). H3K27 trimethylation is a repressive epigenetic mark controlling chromatin organization and gene silencing. This protein can also demethylate non-histone proteins such as retinoblastoma protein. Through its demethylation actvity this gene influences cellular differentiation and development, tumorigenesis, inflammatory diseases, and neurodegenerative diseases. This protein has two classical nuclear localization signals at its N-terminus. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
GeneCards Summary for KDM6B Gene
KDM6B (Lysine Demethylase 6B) is a Protein Coding gene. Diseases associated with KDM6B include Neurodevelopmental Disorder With Coarse Facies And Mild Distal Skeletal Abnormalities and Brain Stem Cancer. Among its related pathways are Chromatin organization and Pathways Affected in Adenoid Cystic Carcinoma. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and dioxygenase activity. An important paralog of this gene is KDM6A.
UniProtKB/Swiss-Prot Summary for KDM6B Gene
-
Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code (PubMed:17825402, PubMed:17851529, PubMed:17713478, PubMed:18003914). Demethylates trimethylated and dimethylated H3 'Lys-27' (PubMed:17825402, PubMed:17851529, PubMed:17713478, PubMed:18003914). Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529). Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation (PubMed:17825402). Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression by acting as a link between T-box factors and the SMARCA4-containing SWI/SNF remodeling complex (By similarity).
-
Histone demethylases (KDMs) are a family of enzymes that catalyze the removal of methyl groups from lysine and arginine residues on histone tails. They reverse the methylation of lysine and arginine residues that is catalyzed by histone methyltransferases.
Additional gene information for KDM6B Gene
- Monarch Initiative
- Search for KDM6B at DataMed
- Search for KDM6B at HumanCyc
No data available for CIViC Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for KDM6B Gene
Genomics for KDM6B Gene
GeneHancer (GH) Regulatory Elements for KDM6B Gene
Promoters and enhancers for KDM6B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around KDM6B on UCSC Golden Path with GeneCards custom track
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for KDM6B
- Top Transcription factor binding sites by QIAGEN in the KDM6B gene promoter:
-
- c-Ets-1
- HNF-4alpha1
- HNF-4alpha2
- LCR-F1
- NF-kappaB
- NF-kappaB1
- Nkx2-5
- Olf-1
- Pax-6
- XBP-1
Genomic Locations for KDM6B Gene
Genomic Locations for KDM6B Gene
- chr17:7,834,200-7,854,800
- (GRCh38/hg38)
- Size:
- 20,601 bases
- Orientation:
- Plus strand
- chr17:7,743,222-7,758,118
- (GRCh37/hg19)
- Size:
- 14,897 bases
- Orientation:
- Plus strand
Genomic View for KDM6B Gene
Genes around KDM6B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17p13.1 by HGNC
- 17p13.1 by Entrez Gene
- 17p13.1 by Ensembl
KDM6B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for KDM6B Gene
Proteins for KDM6B Gene
-
Protein details for KDM6B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O15054-KDM6B_HUMAN
- Recommended name:
- Lysine-specific demethylase 6B
- Protein Accession:
- O15054
- C9IZ40
- Q96G33
Protein attributes for KDM6B Gene
- Size:
- 1643 amino acids
- Molecular mass:
- 176632 Da
- Cofactor:
- Name=L-ascorbate; Xref=ChEBI:CHEBI:38290;
- Cofactor:
- Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
- Quaternary structure:
-
- Interacts with TLE1 (By similarity). Component of the MLL4 complex, at least composed of KMT2B/MLL4, ASH2L, RBBP5, WDR5, and KDM6B (PubMed:17825402). Interacts with TBX21, SMARCA4, SMARCC1 and SMARCC2 (By similarity).
- SequenceCaution:
-
- Sequence=BAA21572.2; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
Three dimensional structures from OCA and Proteopedia for KDM6B Gene
Protein Expression for KDM6B Gene
Selected DME Specific Peptides for KDM6B Gene
- O15054:
-
- QRPGDLVWINAGTVHWVQA
- GWCNNIAWNVGPLTA
- KLNPPTPSIYLE
- IKFGTNIDLSD
- SHTTIAKYAQYQA
Post-translational modifications for KDM6B Gene
Other Protein References for KDM6B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- NSJ Bioreagents JMJD3 Antibody
- Creative Diagnostics Anti-KDM6B monoclonal antibody, clone 4K8 and Rabbit Anti-Mouse Kdm6b Polyclonal Antibody
- GeneTex Anti-JMJD3 antibody [C2], C-term and Anti-JMJD3 antibody
- Novus Biologicals Antibodies for KDM6B
-
Abcam antibodies for KDM6B
- Invitrogen Antibodies for KDM6B (AFLGC-KDM6B)
-
Biorbyt antibodies for KDM6B
-
Custom Antibody ServicesProSci Antibodies for KDM6B
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for KDM6B
- Origene Custom Protein Services for KDM6B
- Novus Biologicals proteins for KDM6B
-
Abcam proteins for KDM6B
Assay Products
- antibodies-online: Show 2 available Kdm6b Elisa Kits ranked by validation data
- Compare Top Kdm6b Elisa Kits
-
Quality Products:
Domains & Families for KDM6B Gene
Gene Families for KDM6B Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for KDM6B Gene
Suggested Antigen Peptide Sequences for KDM6B Gene
- GenScript: Design optimal peptide antigens:
-
- Lysine demethylase 6B (KDM6B_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O15054- Family:
-
- Belongs to the UTX family.
Function for KDM6B Gene
Molecular function for KDM6B Gene
- UniProtKB/Swiss-Prot Function:
- Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code (PubMed:17825402, PubMed:17851529, PubMed:17713478, PubMed:18003914). Demethylates trimethylated and dimethylated H3 'Lys-27' (PubMed:17825402, PubMed:17851529, PubMed:17713478, PubMed:18003914). Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529). Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation (PubMed:17825402). Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression by acting as a link between T-box factors and the SMARCA4-containing SWI/SNF remodeling complex (By similarity).
- UniProtKB/Swiss-Prot Induction:
- By 12-O-tetradecanoylphorbol-13-acetate (TPA) in myeloid leukemia cells.
Enzyme Numbers (IUBMB) for KDM6B Gene
Phenotypes From GWAS Catalog for KDM6B Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IBA | 21873635 |
| GO:0003682 | chromatin binding | IBA | 21873635 |
| GO:0005515 | protein binding | IPI | 21841772 |
| GO:0008013 | beta-catenin binding | IEA | -- |
| GO:0016491 | oxidoreductase activity | IEA | -- |
Phenotypes for KDM6B Gene
- MGI mutant phenotypes for KDM6B:
-
inferred from 9 alleles
- cardiovascular system phenotype
- respiratory system phenotype
- limbs/digits/tail phenotype
- homeostasis/metabolism phenotype
- nervous system phenotype
- no phenotypic analysis
- endocrine/exocrine gland phenotype
- mortality/aging
- cellular phenotype
- reproductive system phenotype
- skeleton phenotype
- hematopoietic system phenotype
- immune system phenotype
- growth/size/body region phenotype
- GenomeRNAi human phenotypes for KDM6B:
Animal Models for KDM6B Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for KDM6B - Select products 50% OFF >
- * KDM6B CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * KDM6B CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for KDM6B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for KDM6B
- genomics-online: gRNA clones - Search for available Kdm6b gRNA products
- Overview of 68 available Kdm6b gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for KDM6B
miRNA for KDM6B Gene
- miRTarBase miRNAs that target KDM6B
-
- hsa-mir-335-5p (MIRT017568)
- hsa-mir-186-5p (MIRT021179)
- hsa-mir-101-3p (MIRT027296)
- hsa-mir-18a-3p (MIRT040965)
- hsa-mir-92a-3p (MIRT049017)
- hsa-let-7a-5p (MIRT052574)
- hsa-mir-5787 (MIRT079165)
- hsa-mir-17-5p (MIRT289570)
- hsa-mir-20a-5p (MIRT289571)
- hsa-mir-93-5p (MIRT289573)
- hsa-mir-106a-5p (MIRT289575)
- hsa-mir-106b-5p (MIRT289577)
- hsa-mir-20b-5p (MIRT289579)
- hsa-mir-526b-3p (MIRT289581)
- hsa-mir-519d-3p (MIRT289583)
- hsa-mir-941 (MIRT289587)
- hsa-mir-127-5p (MIRT440397)
- hsa-mir-3175 (MIRT493410)
- hsa-mir-3178 (MIRT493411)
- hsa-mir-6731-5p (MIRT493412)
- hsa-mir-8085 (MIRT493413)
- hsa-mir-4749-5p (MIRT493414)
- hsa-mir-4706 (MIRT493415)
- hsa-mir-2277-5p (MIRT493416)
- hsa-mir-4746-5p (MIRT493417)
- hsa-mir-6889-5p (MIRT493418)
- hsa-mir-6777-5p (MIRT493419)
- hsa-mir-6791-5p (MIRT493420)
- hsa-mir-4292 (MIRT493421)
- hsa-mir-4308 (MIRT493422)
- hsa-mir-3940-3p (MIRT493423)
- hsa-mir-7109-5p (MIRT570644)
- hsa-mir-4472 (MIRT570645)
- hsa-mir-6771-5p (MIRT570646)
- hsa-mir-4447 (MIRT570647)
- hsa-mir-7704 (MIRT570648)
- hsa-mir-615-5p (MIRT570649)
- hsa-mir-6885-5p (MIRT570650)
- hsa-mir-328-5p (MIRT570651)
- hsa-mir-6887-5p (MIRT570652)
- hsa-mir-6795-5p (MIRT570653)
- hsa-mir-4652-5p (MIRT570654)
- hsa-mir-8052 (MIRT570655)
- hsa-mir-3199 (MIRT570656)
- hsa-mir-4515 (MIRT570657)
- hsa-mir-4745-5p (MIRT570658)
- hsa-mir-4481 (MIRT570659)
- hsa-mir-7152-3p (MIRT570660)
- hsa-mir-6746-5p (MIRT570661)
- hsa-mir-1296-3p (MIRT570662)
- mmu-mir-20a-5p (MIRT735174)
- hsa-mir-1203 (MIRT735963)
- hsa-mir-1267 (MIRT736710)
- hsa-mir-1286 (MIRT737054)
- hsa-mir-146a-5p (MIRT737642)
- hsa-mir-146b-5p (MIRT737649)
- hsa-mir-149-3p (MIRT737740)
- hsa-mir-29a-3p (MIRT739567)
- hsa-mir-29b-3p (MIRT739590)
- hsa-mir-29c-3p (MIRT739602)
- hsa-mir-3135b (MIRT740131)
- hsa-mir-3648 (MIRT741863)
- hsa-mir-3652 (MIRT741893)
- hsa-mir-3663-3p (MIRT742006)
- hsa-mir-367-5p (MIRT742143)
- hsa-mir-4430 (MIRT744331)
- hsa-mir-4501 (MIRT745497)
- hsa-mir-4711-3p (MIRT747436)
- hsa-mir-4722-5p (MIRT747600)
- hsa-mir-4728-5p (MIRT747836)
- hsa-mir-4767 (MIRT748602)
- hsa-mir-505-5p (MIRT749583)
- hsa-mir-519a-3p (MIRT750109)
- hsa-mir-519b-3p (MIRT750127)
- hsa-mir-519c-3p (MIRT750145)
- hsa-mir-581 (MIRT751508)
- hsa-mir-589-5p (MIRT751569)
- hsa-mir-592 (MIRT751585)
- hsa-mir-6090 (MIRT752038)
- hsa-mir-6783-5p (MIRT755750)
- hsa-mir-6785-5p (MIRT755831)
- hsa-mir-6808-3p (MIRT756547)
- hsa-mir-6824-5p (MIRT756945)
- hsa-mir-6825-5p (MIRT756988)
- hsa-mir-6846-3p (MIRT757420)
- hsa-mir-6859-3p (MIRT757807)
- hsa-mir-6883-5p (MIRT758416)
- hsa-mir-7153-5p (MIRT759206)
- hsa-mir-767-5p (MIRT759678)
- hsa-mir-7973 (MIRT759970)
- hsa-mir-8055 (MIRT760023)
- hsa-mir-873-5p (MIRT760312)
- hsa-mir-1178-3p (MIRT761178)
- hsa-mir-125a-3p (MIRT761668)
- hsa-mir-143-5p (MIRT762683)
- hsa-mir-148a-3p (MIRT762748)
- hsa-mir-148b-3p (MIRT762758)
- hsa-mir-152-3p (MIRT762890)
- hsa-mir-185-3p (MIRT763168)
- hsa-mir-1913 (MIRT763390)
- hsa-mir-210-5p (MIRT763778)
- hsa-mir-3151-5p (MIRT765042)
- hsa-mir-324-3p (MIRT765567)
- hsa-mir-331-3p (MIRT765634)
- hsa-mir-3620-3p (MIRT766109)
- hsa-mir-381-5p (MIRT767549)
- hsa-mir-3934-5p (MIRT767834)
- hsa-mir-423-5p (MIRT767946)
- hsa-mir-4283 (MIRT768371)
- hsa-mir-4433a-3p (MIRT769010)
- hsa-mir-4466 (MIRT769433)
- hsa-mir-4489 (MIRT769701)
- hsa-mir-4492 (MIRT769717)
- hsa-mir-4498 (MIRT769751)
- hsa-mir-4505 (MIRT769826)
- hsa-mir-4524a-3p (MIRT770010)
- hsa-mir-4700-3p (MIRT771291)
- hsa-mir-4731-5p (MIRT771780)
- hsa-mir-4737 (MIRT771817)
- hsa-mir-4749-3p (MIRT771926)
- hsa-mir-486-3p (MIRT772674)
- hsa-mir-5001-5p (MIRT772916)
- hsa-mir-6499-3p (MIRT776283)
- hsa-mir-675-5p (MIRT778392)
- hsa-mir-6784-3p (MIRT779086)
- hsa-mir-6804-5p (MIRT779514)
- hsa-mir-6852-5p (MIRT780457)
- hsa-mir-6862-3p (MIRT780596)
- hsa-mir-6865-3p (MIRT780646)
- hsa-mir-762 (MIRT781790)
- hsa-mir-764 (MIRT781812)
- hsa-mir-92a-2-5p (MIRT782661)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for KDM6B
- Browse OriGene Inhibitory RNA Products For KDM6B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KDM6B
- genomics-online: shRNA clones - Search for available Kdm6b shRNA products
- Overview of 68 available Kdm6b gene related products
Clone Products
- Applied Biological Materials (abm): Clones for KDM6B - Select products 50% OFF >
- * KDM6B as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * KDM6B tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
- Sino Biological Human cDNA Clone for KDM6B
- Addgene plasmids for KDM6B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for KDM6B
- genomics-online: cdna clones - Search for available Kdm6b CDNA products
- Overview of 68 available Kdm6b gene related products
- orf clones - Search for available Kdm6b ORF products
- Overview of 68 available Kdm6b gene related products
Cell Line Products
-
Horizon Cell Lines for KDM6B
No data available for Transcription Factor Targets and HOMER Transcription for KDM6B Gene
Localization for KDM6B Gene
Subcellular locations from UniProtKB/Swiss-Prot for KDM6B Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| extracellular | 3 |
| plasma membrane | 2 |
| cytoskeleton | 2 |
| mitochondrion | 2 |
| cytosol | 2 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
- Nuclear speckles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000790 | nuclear chromatin | IBA | 21873635 |
| GO:0005634 | nucleus | IEA,ISS | 23856522 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0044666 | MLL3/4 complex | IBA | 21873635 |
Pathways & Interactions for KDM6B Gene
Pathways by source for KDM6B Gene
1 BioSystems pathway for KDM6B Gene
6 Reactome pathways for KDM6B Gene
1 Cell Signaling Technology pathway for KDM6B Gene
1 GeneTex pathway for KDM6B Gene
Interacting Proteins for KDM6B Gene
Selected Interacting proteins:
O15054-KDM6B_HUMAN
ENSP00000254846
for KDM6B Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for KDM6B
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002437 | inflammatory response to antigenic stimulus | IEA | -- |
| GO:0006325 | chromatin organization | IEA | -- |
| GO:0006338 | chromatin remodeling | ISS | -- |
| GO:0006954 | inflammatory response | IEA | -- |
| GO:0010468 | regulation of gene expression | IEA | -- |
Drugs & Compounds for KDM6B Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Daminozide | Pharma | KDM2A inhibitor, Selective KDM2/7 inhibitor | 16 | |||
| GSK J1 | Pharma | H3K27 demethylase JMJD3 inhibitor, Potent JMJD3/UTX inhibitor | 0 | |||
| GSK J4 free base | Pharma | 0 | ||||
| GSK J4 HCl | Pharma | Inhibitor of H3K27 demethylase JMJD3,potent and cell-permeable | 0 | |||
| JIB-04 | Pharma | Jumonji histone demethylase inihibitor | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| GSK J4 |
|
1373423-53-0 |
|
|
(5) Tocris Compounds for KDM6B Gene
| Compound | Action | Cas Number |
|---|---|---|
| Daminozide | Selective KDM2/7 inhibitor | 1596-84-5 |
| GSK J1 | Potent JMJD3/UTX inhibitor | 1373422-53-7 |
| GSK J4 | Histone KDM inhibitor; cell permeable | 1373423-53-0 |
| IOX 1 | Histone demethylase inhibitor; cell permeable | 5852-78-8 |
| Tranylcypromine hydrochloride | Irreversible inhibitor of LSD1; also inhibits MAO | 1986-47-6 |
(5) ApexBio Compounds for KDM6B Gene
| Compound | Action | Cas Number |
|---|---|---|
| Daminozide | KDM2A inhibitor | 1596-84-5 |
| GSK J1 | H3K27 demethylase JMJD3 inhibitor | 1373422-53-7 |
| GSK J4 free base | ||
| GSK J4 HCl | Inhibitor of H3K27 demethylase JMJD3,potent and cell-permeable | 1373423-53-0 |
| JIB-04 | Jumonji histone demethylase inihibitor | 199596-05-9 |
Transcripts for KDM6B Gene
mRNA/cDNA for KDM6B Gene
- 2 REFSEQ mRNAs :
- 3 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000254846 6713 bps (ENST00000254846.9)
- ENST00000448097 5422 bps (ENST00000448097.6)
- ENST00000570632 1339 bps (ENST00000570632.1)
- ENST00000571047 362 bps (ENST00000571047.5)
- ENST00000572030 432 bps (ENST00000572030.1)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for KDM6B - Select products 50% OFF >
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- * KDM6B CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for KDM6B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for KDM6B
- genomics-online: gRNA clones - Search for available Kdm6b gRNA products
- Overview of 68 available Kdm6b gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for KDM6B
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for KDM6B
- Browse OriGene Inhibitory RNA Products For KDM6B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KDM6B
- genomics-online: shRNA clones - Search for available Kdm6b shRNA products
- Overview of 68 available Kdm6b gene related products
Clone Products
- Applied Biological Materials (abm): Clones for KDM6B - Select products 50% OFF >
- * KDM6B as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * KDM6B tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
- Sino Biological Human cDNA Clone for KDM6B
- Addgene plasmids for KDM6B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for KDM6B
- genomics-online: cdna clones - Search for available Kdm6b CDNA products
- Overview of 68 available Kdm6b gene related products
- orf clones - Search for available Kdm6b ORF products
- Overview of 68 available Kdm6b gene related products
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP5: |
Relevant External Links for KDM6B Gene
- GeneLoc Exon Structure for
- KDM6B
Expression for KDM6B Gene
mRNA differential expression in normal tissues according to GTEx for KDM6B Gene
This gene is overexpressed in Whole Blood (x7.8).
This gene is overexpressed in Serum (36.7) and Cervix (21.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for KDM6B Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for KDM6B
SOURCE GeneReport for Unigene cluster for KDM6B Gene:
Hs.223678Evidence on tissue expression from TISSUES for KDM6B Gene
- Nervous system(4.5)
- Lung(2.1)
Primer Products
-
OriGene qPCR primer pairs for KDM6B