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Aliases for KDM4C Gene

Aliases for KDM4C Gene

  • Lysine Demethylase 4C 2 3 5
  • JmjC Domain-Containing Histone Demethylation Protein 3C 3 4
  • Gene Amplified In Squamous Cell Carcinoma 1 Protein 3 4
  • Jumonji Domain-Containing Protein 2C 3 4
  • Lysine (K)-Specific Demethylase 4C 2 3
  • Tudor Domain Containing 14C 2 3
  • JMJD2C 3 4
  • JHDM3C 3 4
  • GASC1 3 4
  • Lysine-Specific Demethylase 4C 3
  • Jumonji Domain Containing 2C 2
  • GASC-1 Protein 4
  • EC 1.14.11.- 4
  • KIAA0780 4
  • TDRD14C 3

External Ids for KDM4C Gene

Previous HGNC Symbols for KDM4C Gene

  • JMJD2C

Previous GeneCards Identifiers for KDM4C Gene

  • GC09P006747
  • GC09P006676

Summaries for KDM4C Gene

Entrez Gene Summary for KDM4C Gene

  • This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

GeneCards Summary for KDM4C Gene

KDM4C (Lysine Demethylase 4C) is a Protein Coding gene. Diseases associated with KDM4C include Squamous Cell Carcinoma. Among its related pathways are Signaling by Rho GTPases and Coregulation of Androgen receptor activity. Gene Ontology (GO) annotations related to this gene include enzyme binding and dioxygenase activity. An important paralog of this gene is KDM4B.

UniProtKB/Swiss-Prot for KDM4C Gene

  • Histone demethylase that specifically demethylates Lys-9 and Lys-36 residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 Lys-4, H3 Lys-27 nor H4 Lys-20. Demethylates trimethylated H3 Lys-9 and H3 Lys-36 residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

Gene Wiki entry for KDM4C Gene

Additional gene information for KDM4C Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KDM4C Gene

Genomics for KDM4C Gene

GeneHancer (GH) Regulatory Elements for KDM4C Gene

Promoters and enhancers for KDM4C Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J006755 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 692.3 +37.1 37137 4.5 HDGF PKNOX1 CLOCK SMAD1 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 KDM4C UHRF2 AK4P4 GLDC ENSG00000236924 SNRPEP2 PIR49656
GH09J006703 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 650.4 -16.7 -16743 1.7 HDGF PKNOX1 CLOCK SMAD1 ARID4B SIN3A IRF4 YY1 GLIS2 ZNF207 LOC105375968 KDM4C GLDC ENSG00000236924 ENSG00000225489 SNRPEP2 GC09P006678
GH09J006715 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 650.7 -4.4 -4432 2.5 HDGF CLOCK FOXA2 SMAD1 ARNT MLX ARID4B SIN3A DMAP1 YBX1 ENSG00000225489 KDM4C LOC105375968 SNRPEP2
GH09J006411 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 10.2 -307.1 -307114 4 HDGF PKNOX1 FOXA2 SMAD1 ARID4B SIN3A DMAP1 IRF4 YY1 ZNF207 UHRF2 RIC1 AK4P4 ENSG00000233367 KDM4C
GH09J006786 Enhancer 1.3 Ensembl ENCODE dbSUPER 11.5 +67.5 67543 3.3 FOXA2 MLX ARID4B SIN3A ETS1 YY1 RXRA REST NFIL3 KDM1A SNRPEP2 KDM4C PIR49656
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around KDM4C on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the KDM4C gene promoter:
  • SREBP-1c
  • SREBP-1b
  • SREBP-1a
  • Evi-1
  • CUTL1
  • STAT1
  • STAT1alpha
  • STAT1beta
  • SRF
  • SRF (504 AA)

Genomic Locations for KDM4C Gene

Genomic Locations for KDM4C Gene
chr9:6,720,863-7,175,648
(GRCh38/hg38)
Size:
454,786 bases
Orientation:
Plus strand
chr9:6,720,863-7,175,648
(GRCh37/hg19)
Size:
454,786 bases
Orientation:
Plus strand

Genomic View for KDM4C Gene

Genes around KDM4C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KDM4C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KDM4C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KDM4C Gene

Proteins for KDM4C Gene

  • Protein details for KDM4C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H3R0-KDM4C_HUMAN
    Recommended name:
    Lysine-specific demethylase 4C
    Protein Accession:
    Q9H3R0
    Secondary Accessions:
    • B4E1Y4
    • B7ZL46
    • F5H347
    • F5H7P0
    • O94877
    • Q2M3M0
    • Q5JUC9
    • Q5VYJ2
    • Q5VYJ3

    Protein attributes for KDM4C Gene

    Size:
    1056 amino acids
    Molecular mass:
    119982 Da
    Cofactor:
    Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA34500.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAI39608.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for KDM4C Gene

    Alternative splice isoforms for KDM4C Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KDM4C Gene

Post-translational modifications for KDM4C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for KDM4C Gene

Domains & Families for KDM4C Gene

Gene Families for KDM4C Gene

HGNC:
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins

Suggested Antigen Peptide Sequences for KDM4C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H3R0

UniProtKB/Swiss-Prot:

KDM4C_HUMAN :
  • The 2 Tudor domains recognize and bind methylated histones. Double Tudor domain has an interdigitated structure and the unusual fold is required for its ability to bind methylated histone tails (By similarity).
  • Belongs to the JHDM3 histone demethylase family.
Domain:
  • The 2 Tudor domains recognize and bind methylated histones. Double Tudor domain has an interdigitated structure and the unusual fold is required for its ability to bind methylated histone tails (By similarity).
Family:
  • Belongs to the JHDM3 histone demethylase family.
genes like me logo Genes that share domains with KDM4C: view

Function for KDM4C Gene

Molecular function for KDM4C Gene

UniProtKB/Swiss-Prot Function:
Histone demethylase that specifically demethylates Lys-9 and Lys-36 residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 Lys-4, H3 Lys-27 nor H4 Lys-20. Demethylates trimethylated H3 Lys-9 and H3 Lys-36 residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

Enzyme Numbers (IUBMB) for KDM4C Gene

Phenotypes From GWAS Catalog for KDM4C Gene

Gene Ontology (GO) - Molecular Function for KDM4C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003682 chromatin binding IEA --
GO:0008270 zinc ion binding IDA 21914792
GO:0016491 oxidoreductase activity IEA --
GO:0019899 enzyme binding IPI 17277772
GO:0032452 histone demethylase activity TAS --
genes like me logo Genes that share ontologies with KDM4C: view
genes like me logo Genes that share phenotypes with KDM4C: view

Animal Models for KDM4C Gene

MGI Knock Outs for KDM4C:
  • Kdm4c Kdm4c<tm1a(KOMP)Wtsi>
  • Kdm4c Kdm4c<tm1d(KOMP)Wtsi>

Animal Model Products

miRNA for KDM4C Gene

miRTarBase miRNAs that target KDM4C

Clone Products

  • Addgene plasmids for KDM4C

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for KDM4C Gene

Localization for KDM4C Gene

Subcellular locations from UniProtKB/Swiss-Prot for KDM4C Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KDM4C gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for KDM4C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000790 nuclear chromatin IDA 17277772
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm TAS --
GO:0005721 pericentric heterochromatin IEA --
genes like me logo Genes that share ontologies with KDM4C: view

Pathways & Interactions for KDM4C Gene

genes like me logo Genes that share pathways with KDM4C: view

Gene Ontology (GO) - Biological Process for KDM4C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001825 blastocyst formation IEA --
GO:0006325 chromatin organization IEA --
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006357 regulation of transcription by RNA polymerase II IDA 17277772
genes like me logo Genes that share ontologies with KDM4C: view

No data available for SIGNOR curated interactions for KDM4C Gene

Drugs & Compounds for KDM4C Gene

No Compound Related Data Available

Transcripts for KDM4C Gene

Unigene Clusters for KDM4C Gene

Lysine (K)-specific demethylase 4C:
Representative Sequences:

Clone Products

  • Addgene plasmids for KDM4C

Alternative Splicing Database (ASD) splice patterns (SP) for KDM4C Gene

No ASD Table

Relevant External Links for KDM4C Gene

GeneLoc Exon Structure for
KDM4C
ECgene alternative splicing isoforms for
KDM4C

Expression for KDM4C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for KDM4C Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for KDM4C Gene

This gene is overexpressed in Nasal epithelium (54.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for KDM4C Gene



NURSA nuclear receptor signaling pathways regulating expression of KDM4C Gene:

KDM4C

SOURCE GeneReport for Unigene cluster for KDM4C Gene:

Hs.709425

mRNA Expression by UniProt/SwissProt for KDM4C Gene:

Q9H3R0-KDM4C_HUMAN
Tissue specificity: Overexpressed in several esophageal squamous cell carcinomas (ESCs).

Evidence on tissue expression from TISSUES for KDM4C Gene

  • Nervous system(4.6)
  • Liver(4.2)
genes like me logo Genes that share expression patterns with KDM4C: view

No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for KDM4C Gene

Orthologs for KDM4C Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for KDM4C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KDM4C 34 33
  • 99.08 (n)
OneToOne
dog
(Canis familiaris)
Mammalia KDM4C 34 33
  • 89.65 (n)
OneToOne
cow
(Bos Taurus)
Mammalia KDM4C 34 33
  • 86.6 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Kdm4c 33
  • 84.59 (n)
mouse
(Mus musculus)
Mammalia Kdm4c 16 34 33
  • 83.97 (n)
oppossum
(Monodelphis domestica)
Mammalia KDM4C 34
  • 78 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 22 (a)
ManyToMany
chicken
(Gallus gallus)
Aves KDM4C 34 33
  • 74.52 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KDM4C 34
  • 76 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kdm4c 33
  • 68.21 (n)
Str.16473 33
zebrafish
(Danio rerio)
Actinopterygii zgc:153957 33
  • 64.9 (n)
KDM4C 34
  • 42 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta Kdm4A 34
  • 47 (a)
ManyToMany
Kdm4B 34
  • 40 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea jmjd-2 34
  • 32 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RPH1 36 34
  • 26 (a)
GIS1 34
  • 18 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10508 34
  • 40 (a)
OneToMany
Cin.8892 33
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.8892 33
Species where no ortholog for KDM4C was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for KDM4C Gene

ENSEMBL:
Gene Tree for KDM4C (if available)
TreeFam:
Gene Tree for KDM4C (if available)
Aminode:
Evolutionary constrained regions (ECRs) for KDM4C: view image

Paralogs for KDM4C Gene

Paralogs for KDM4C Gene

(7) SIMAP similar genes for KDM4C Gene using alignment to 6 proteins:

  • KDM4C_HUMAN
  • B0QZ60_HUMAN
  • C9J879_HUMAN
  • E7EV17_HUMAN
  • F5GYH2_HUMAN
  • F8WCN1_HUMAN
genes like me logo Genes that share paralogs with KDM4C: view

Variants for KDM4C Gene

Sequence variations from dbSNP and Humsavar for KDM4C Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000007355 -- 7,020,223(+) C/G genic_downstream_transcript_variant, intron_variant
rs1000008183 -- 6,991,699(+) C/T genic_downstream_transcript_variant, intron_variant
rs1000013748 -- 7,144,643(+) C/G genic_downstream_transcript_variant, intron_variant
rs1000021492 -- 6,830,005(+) C/G genic_downstream_transcript_variant, genic_upstream_transcript_variant, intron_variant
rs1000022519 -- 7,044,984(+) G/T genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for KDM4C Gene

Variant ID Type Subtype PubMed ID
dgv12488n54 CNV gain 21841781
dgv12494n54 CNV loss 21841781
dgv1435e214 CNV loss 21293372
dgv3949n106 CNV deletion 24896259
dgv3950n106 CNV deletion 24896259
dgv3951n106 CNV deletion 24896259
dgv7388n100 CNV gain 25217958
dgv7390n100 CNV loss 25217958
dgv7391n100 CNV loss 25217958
dgv7392n100 CNV loss 25217958
esv1002679 CNV deletion 20482838
esv1268323 CNV insertion 17803354
esv1403882 CNV deletion 17803354
esv1599076 CNV deletion 17803354
esv2205276 CNV deletion 18987734
esv2365258 CNV deletion 18987734
esv2426665 CNV deletion 19546169
esv2502836 CNV deletion 19546169
esv2537839 CNV deletion 19546169
esv2575633 CNV deletion 19546169
esv2662375 CNV deletion 23128226
esv26908 CNV loss 19812545
esv2738170 CNV deletion 23290073
esv2738171 CNV deletion 23290073
esv2738172 CNV deletion 23290073
esv2752308 CNV gain 17911159
esv2752309 CNV gain 17911159
esv2759661 CNV loss 17122850
esv2759662 CNV loss 17122850
esv2761485 CNV gain 21179565
esv27835 CNV loss 19812545
esv32977 CNV loss 17666407
esv3302831 CNV tandem duplication 20981092
esv3422925 CNV insertion 20981092
esv35116 CNV loss 17911159
esv3544475 CNV deletion 23714750
esv3544479 CNV deletion 23714750
esv3544481 CNV deletion 23714750
esv3573101 CNV loss 25503493
esv3573102 CNV loss 25503493
esv3573103 CNV loss 25503493
esv3576621 CNV gain 25503493
esv3576622 CNV gain 25503493
esv3619411 CNV gain 21293372
esv3619434 CNV gain 21293372
esv3619435 CNV loss 21293372
esv3619437 CNV gain 21293372
esv3619438 CNV loss 21293372
esv3619439 CNV loss 21293372
esv3619440 CNV gain 21293372
esv3619441 CNV gain 21293372
esv3619444 CNV gain 21293372
esv3619446 CNV loss 21293372
esv3619447 CNV gain 21293372
esv3619449 CNV loss 21293372
esv3619450 CNV gain 21293372
esv3619451 CNV gain 21293372
esv3619454 CNV loss 21293372
esv3619455 CNV gain 21293372
esv3619456 CNV loss 21293372
esv3619457 CNV loss 21293372
esv3891542 CNV loss 25118596
esv3891544 CNV loss 25118596
esv3891545 CNV loss 25118596
esv4186 CNV loss 18987735
esv4579 CNV loss 18987735
esv8547 CNV loss 19470904
esv9139 CNV loss 19470904
esv991061 CNV insertion 20482838
nsv1016109 CNV gain 25217958
nsv1018732 CNV gain 25217958
nsv1018845 CNV gain 25217958
nsv1021016 CNV gain 25217958
nsv1021234 CNV gain 25217958
nsv1023461 CNV loss 25217958
nsv1023706 CNV gain 25217958
nsv1023906 CNV loss 25217958
nsv1024763 CNV loss 25217958
nsv1025847 CNV loss 25217958
nsv1029665 CNV gain 25217958
nsv1030278 CNV gain 25217958
nsv1032676 CNV gain 25217958
nsv1033539 CNV gain 25217958
nsv1074279 CNV deletion 25765185
nsv1074284 CNV deletion 25765185
nsv1077088 CNV deletion 25765185
nsv1111368 CNV tandem duplication 24896259
nsv1125963 CNV tandem duplication 24896259
nsv1132184 CNV deletion 24896259
nsv1148202 CNV deletion 26484159
nsv416139 CNV deletion 16902084
nsv466111 CNV gain 19166990
nsv466112 CNV gain 19166990
nsv466113 CNV loss 19166990
nsv466114 CNV loss 19166990
nsv466115 CNV gain 19166990
nsv466117 CNV gain 19166990
nsv471273 CNV loss 18288195
nsv477027 CNV novel sequence insertion 20440878
nsv477375 CNV novel sequence insertion 20440878
nsv512087 CNV loss 21212237
nsv519762 CNV loss 19592680
nsv519777 CNV gain 19592680
nsv522977 CNV loss 19592680
nsv523788 CNV loss 19592680
nsv524069 CNV gain 19592680
nsv524896 CNV gain 19592680
nsv528873 CNV loss 19592680
nsv613208 CNV gain 21841781
nsv613212 CNV gain 21841781
nsv613213 CNV loss 21841781
nsv613218 CNV loss 21841781
nsv613252 CNV gain 21841781
nsv613255 CNV loss 21841781
nsv613256 CNV gain 21841781
nsv613257 CNV loss 21841781
nsv613258 CNV gain 21841781
nsv613259 CNV gain 21841781
nsv818679 CNV loss 17921354
nsv820480 CNV deletion 20802225
nsv824840 CNV loss 20364138
nsv824841 CNV loss 20364138
nsv831499 CNV loss 17160897
nsv831500 CNV loss 17160897
nsv831501 CNV gain 17160897
nsv957707 CNV deletion 24416366
nsv957736 CNV deletion 24416366
nsv968594 CNV duplication 23825009
nsv982194 CNV duplication 23825009
nsv982630 CNV duplication 23825009

Variation tolerance for KDM4C Gene

Residual Variation Intolerance Score: 6.94% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 15.07; 96.89% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for KDM4C Gene

Human Gene Mutation Database (HGMD)
KDM4C
SNPedia medical, phenotypic, and genealogical associations of SNPs for
KDM4C

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KDM4C Gene

Disorders for KDM4C Gene

MalaCards: The human disease database

(1) MalaCards diseases for KDM4C Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
squamous cell carcinoma
  • epidermoid carcinoma
- elite association - COSMIC cancer census association via MalaCards
Search KDM4C in MalaCards View complete list of genes associated with diseases

Additional Disease Information for KDM4C

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with KDM4C: view

No data available for UniProtKB/Swiss-Prot and Genatlas for KDM4C Gene

Publications for KDM4C Gene

  1. Identification and characterization of JMJD2 family genes in silico. (PMID: 15138608) Katoh M … Katoh M (International journal of oncology 2004) 2 3 22 58
  2. Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 9872452) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 1998) 2 3 4 58
  3. Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells. (PMID: 28262558) Tumber A … Brennan PE (Cell chemical biology 2017) 3 4 58
  4. Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family. (PMID: 21914792) Hillringhaus L … Oppermann U (The Journal of biological chemistry 2011) 3 4 58
  5. Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines. (PMID: 20923822) Niu N … Wang L (Genome research 2010) 3 44 58

Products for KDM4C Gene

Sources for KDM4C Gene

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