Aliases for KCNT2 Gene

Aliases for KCNT2 Gene

  • Potassium Sodium-Activated Channel Subfamily T Member 2 2 3 5
  • SLICK 2 3 4
  • Sodium And Chloride-Activated ATP-Sensitive Potassium Channel Slo2.1 3 4
  • Sequence Like An Intermediate Conductance Potassium Channel Subunit 3 4
  • Potassium Channel, Subfamily T, Member 2 2 3
  • Potassium Channel Subfamily T Member 2 3 4
  • KCa4.2 2 3
  • SLO2.1 2 3
  • Sodium-And Chloride-Activated ATP-Sensitive Potassium Channel (SLICK) 3
  • Sodium And Chloride Activated ATP Sensitive Potassium Channel 2
  • Potassium Channel, Sodium Activated Subfamily T, Member 2 2
  • EIEE57 3
  • DEE57 3
  • KCNT2 5

External Ids for KCNT2 Gene

Previous GeneCards Identifiers for KCNT2 Gene

  • GC01M193941
  • GC01U900041
  • GC01M192927
  • GC01M194461
  • GC01M196194
  • GC01M167436

Summaries for KCNT2 Gene

GeneCards Summary for KCNT2 Gene

KCNT2 (Potassium Sodium-Activated Channel Subfamily T Member 2) is a Protein Coding gene. Diseases associated with KCNT2 include Developmental And Epileptic Encephalopathy 57 and Seizure Disorder. Among its related pathways are Neuropathic Pain-Signaling in Dorsal Horn Neurons and Sweet Taste Signaling. Gene Ontology (GO) annotations related to this gene include voltage-gated potassium channel activity and calcium-activated potassium channel activity. An important paralog of this gene is KCNT1.

UniProtKB/Swiss-Prot Summary for KCNT2 Gene

  • Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels (PubMed:14684870, PubMed:16687497, PubMed:29069600). Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (PubMed:16687497) (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRM1 (PubMed:16687497).

Tocris Summary for KCNT2 Gene

  • Calcium (Ca2+) -activated potassium channels (KCa) are a group of 6/7-TM ion channels that selectively transport K+ ions across biological membranes. They are broadly classified into three subtypes: SK, IK and BK channels (small, intermediate and big conductance).

Gene Wiki entry for KCNT2 Gene

No data available for Entrez Gene Summary , CIViC Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for KCNT2 Gene

Genomics for KCNT2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for KCNT2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J196607 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE CraniofacialAtlas 250.7 +1.0 1000 3.2 ATF3 POLR2A YY1 ETS1 ZNF341 SIN3A SP2 JUND PRDM10 ZBTB48 KCNT2 MIR4735
GH01J196516 Enhancer 0.7 Ensembl 11.2 +92.6 92624 1.2 IKZF1 ARNT TAL1 MYNN STAT5A NCOA1 TCF12 HDAC1 DPF2 ARID1B KCNT2 lnc-CFH-3 HSALNG0009414 HSALNG0009413
GH01J196400 Enhancer 1 Ensembl ENCODE 5.7 +208.1 208124 1.4 CEBPA CHD4 YY1 HOMEZ FOXA2 KDM6A SMAD4 RXRA ZBTB33 ETV4 KCNT2 CFHR3 HSALNG0009413 piR-46381-007
GH01J196659 Enhancer 0.4 Ensembl 11.2 -50.4 -50376 0.4 ETV1 RFX1 GABPB1 GABPA KCNT2 CFH NONHSAG003845.2 CFHR3
GH01J196410 Enhancer 0.2 FANTOM5 13 +198.6 198612 0.5 KCNT2 CFHR3 CFH piR-46381-007 HSALNG0009413
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around KCNT2 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for KCNT2

Top Transcription factor binding sites by QIAGEN in the KCNT2 gene promoter:
  • c-Ets-1
  • E47
  • HOXA9
  • HOXA9B
  • Meis-1
  • Meis-1a
  • Pbx1a
  • Tal-1beta
  • TBP
  • TFIID

Genomic Locations for KCNT2 Gene

Latest Assembly
chr1:196,225,779-196,609,225
(GRCh38/hg38)
Size:
383,447 bases
Orientation:
Minus strand

Previous Assembly
chr1:196,194,909-196,577,570
(GRCh37/hg19 by Entrez Gene)
Size:
382,662 bases
Orientation:
Minus strand

chr1:196,194,909-196,578,355
(GRCh37/hg19 by Ensembl)
Size:
383,447 bases
Orientation:
Minus strand

Genomic View for KCNT2 Gene

Genes around KCNT2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KCNT2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KCNT2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KCNT2 Gene

Proteins for KCNT2 Gene

  • Protein details for KCNT2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UVM3-KCNT2_HUMAN
    Recommended name:
    Potassium channel subfamily T member 2
    Protein Accession:
    Q6UVM3
    Secondary Accessions:
    • Q3SY59
    • Q5VTN1
    • Q6ZMT3

    Protein attributes for KCNT2 Gene

    Size:
    1135 amino acids
    Molecular mass:
    130501 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for KCNT2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KCNT2 Gene

Post-translational modifications for KCNT2 Gene

  • Phosphorylated by protein kinase C. Phosphorylation of the C-terminal domain inhibits channel activity.
  • Glycosylation at Asn99
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for KCNT2 Gene

Domains & Families for KCNT2 Gene

Gene Families for KCNT2 Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Transporters
  • Voltage-gated ion channels

Protein Domains for KCNT2 Gene

InterPro:
Blocks:
  • Ion transport 2, bacterial

Suggested Antigen Peptide Sequences for KCNT2 Gene

GenScript: Design optimal peptide antigens:
  • Sodium activated potassium channel (A9LNM6_HUMAN)
  • Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1 (KCNT2_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q6UVM3

UniProtKB/Swiss-Prot:

KCNT2_HUMAN :
  • Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa4.2/KCNT2 sub-subfamily.
Family:
  • Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa4.2/KCNT2 sub-subfamily.
genes like me logo Genes that share domains with KCNT2: view

Function for KCNT2 Gene

Molecular function for KCNT2 Gene

UniProtKB/Swiss-Prot Function:
Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels (PubMed:14684870, PubMed:16687497, PubMed:29069600). Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane (PubMed:16687497) (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRM1 (PubMed:16687497).

Phenotypes From GWAS Catalog for KCNT2 Gene

Gene Ontology (GO) - Molecular Function for KCNT2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0005228 intracellular sodium activated potassium channel activity IBA 21873635
GO:0005267 potassium channel activity IEA --
GO:0005524 ATP binding IEA --
GO:0015271 outward rectifier potassium channel activity IBA 21873635
genes like me logo Genes that share ontologies with KCNT2: view
genes like me logo Genes that share phenotypes with KCNT2: view

Human Phenotype Ontology for KCNT2 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for KCNT2 Gene

MGI Knock Outs for KCNT2:

Animal Models for research

  • Taconic Biosciences Mouse Models for KCNT2

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KCNT2

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for KCNT2 Gene

Localization for KCNT2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for KCNT2 Gene

Cell membrane. Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KCNT2 gene
Compartment Confidence
plasma membrane 5
extracellular 1
cytoskeleton 1
mitochondrion 1
peroxisome 1
nucleus 1
endoplasmic reticulum 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for KCNT2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IBA,IDA 29069600
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA,IBA 21873635
genes like me logo Genes that share ontologies with KCNT2: view

Pathways & Interactions for KCNT2 Gene

PathCards logo

SuperPathways for KCNT2 Gene

SuperPathway Contained pathways
1 Sweet Taste Signaling
.72
.72
.46
.44
.37
2 Activation of cAMP-Dependent PKA
.77
.77
.56
3 Neuropathic Pain-Signaling in Dorsal Horn Neurons
.47
.47
.40
4 Hepatic ABC Transporters
.41
.41
genes like me logo Genes that share pathways with KCNT2: view

Pathways by source for KCNT2 Gene

13 Qiagen pathways for KCNT2 Gene
  • Activation of cAMP-Dependent PKA
  • Aldosterone Signaling in Epithelial Cells
  • Bitter Taste Signaling
  • cAMP Pathway
  • Cellular Effects of Sildenafil

Gene Ontology (GO) - Biological Process for KCNT2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006811 ion transport IEA --
GO:0006813 potassium ion transport IEA --
GO:0071805 potassium ion transmembrane transport IEA --
GO:0097623 potassium ion export across plasma membrane IMP 29069600
genes like me logo Genes that share ontologies with KCNT2: view

No data available for SIGNOR curated interactions for KCNT2 Gene

Drugs & Compounds for KCNT2 Gene

(14) Drugs for KCNT2 Gene - From: PharmGKB, DGIdb, IUPHAR, HMDB, and Tocris

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
tetraethylammonium Experimental, Investigational Pharma Inhibitor, Pore Blocker, Inhibition 1
Chloride ion Experimental Pharma 0
Ba<sup>2+</sup> Pharma Pore Blocker, Inhibition 0
Charybdotoxin Pharma Inhibitor, blocker 0
Iberiotoxin Pharma Inhibitor 0

(1) Additional Compounds for KCNT2 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
sodium
  • Na(+)
  • Na+
  • SODIUM ion
  • Sodium(1+)
7440-23-5

(4) Tocris Compounds for KCNT2 Gene

Compound Action Cas Number
1-EBIO Activator of epithelial KCa channels 10045-45-1
BMS 191011 Potent BKCa (KCa1.1) channel opener 202821-81-6
CyPPA Activator of KCa2.2 and KCa2.3 channels 73029-73-9
SKA 31 Activator of KCa3.1 and KCa2 channels 40172-65-4
genes like me logo Genes that share compounds with KCNT2: view

Transcripts for KCNT2 Gene

mRNA/cDNA for KCNT2 Gene

3 REFSEQ mRNAs :
12 NCBI additional mRNA sequence :
9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KCNT2

Alternative Splicing Database (ASD) splice patterns (SP) for KCNT2 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^
SP1: -
SP2: -

ExUns: 27 ^ 28a · 28b
SP1:
SP2:

Relevant External Links for KCNT2 Gene

GeneLoc Exon Structure for
KCNT2

Expression for KCNT2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for KCNT2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for KCNT2 Gene

This gene is overexpressed in Artery - Coronary (x4.1).

Protein differential expression in normal tissues from HIPED for KCNT2 Gene

This gene is overexpressed in Skin (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for KCNT2 Gene



Protein tissue co-expression partners for KCNT2 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for KCNT2

SOURCE GeneReport for Unigene cluster for KCNT2 Gene:

Hs.657046

Evidence on tissue expression from TISSUES for KCNT2 Gene

  • Nervous system(3.4)
genes like me logo Genes that share expression patterns with KCNT2: view

Primer products for research

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KCNT2 Gene

Orthologs for KCNT2 Gene

This gene was present in the common ancestor of animals.

Orthologs for KCNT2 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia KCNT2 29 30
  • 99.82 (n)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 30
  • 97 (a)
OneToMany
-- 30
  • 95 (a)
OneToMany
-- 30
  • 92 (a)
OneToMany
-- 30
  • 87 (a)
OneToMany
-- 30
  • 86 (a)
OneToMany
-- 30
  • 81 (a)
OneToMany
Oppossum
(Monodelphis domestica)
Mammalia KCNT2 30
  • 95 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia KCNT2 29 30
  • 94.27 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia KCNT2 29 30
  • 92.77 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Kcnt2 29 16 30
  • 90.46 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Kcnt2 29
  • 90.43 (n)
Chicken
(Gallus gallus)
Aves KCNT2 29 30
  • 83.7 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia KCNT2 30
  • 89 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia kcnt1 29
  • 68.85 (n)
Zebrafish
(Danio rerio)
Actinopterygii LOC565691 29
  • 68.67 (n)
kcnt2 30
  • 63 (a)
OneToOne
Fruit Fly
(Drosophila melanogaster)
Insecta CG42732 30
  • 33 (a)
OneToOne
Worm
(Caenorhabditis elegans)
Secernentea slo-2 30
  • 43 (a)
OneToOne
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 30
  • 45 (a)
OneToOne
Species where no ortholog for KCNT2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for KCNT2 Gene

ENSEMBL:
Gene Tree for KCNT2 (if available)
TreeFam:
Gene Tree for KCNT2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for KCNT2: view image
Alliance of Genome Resources:
Additional Orthologs for KCNT2

Paralogs for KCNT2 Gene

Paralogs for KCNT2 Gene

(1) SIMAP similar genes for KCNT2 Gene using alignment to 5 proteins:

  • KCNT2_HUMAN
  • A9LNM6_HUMAN
  • G8JLE3_HUMAN
  • Q3SY61_HUMAN
  • V9GZ63_HUMAN
genes like me logo Genes that share paralogs with KCNT2: view

Variants for KCNT2 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for KCNT2 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
1013545 Uncertain Significance: not provided 196,467,695(-) A/T
NM_198503.5(KCNT2):c.543+8T>A
INTRON
1027925 Uncertain Significance: Developmental and epileptic encephalopathy, 57 196,428,113(-) T/C
NM_198503.5(KCNT2):c.976A>G (p.Arg326Gly)
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT
1033261 Uncertain Significance: Developmental and epileptic encephalopathy, 57 196,373,266(-) G/A
NM_198503.5(KCNT2):c.1295-18C>T
INTRON
1038932 Uncertain Significance: not provided 196,467,711(-) T/A
NM_198503.5(KCNT2):c.535A>T (p.Asn179Tyr)
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT
871207 Uncertain Significance: not provided 196,305,269(-) C/T
NM_198503.5(KCNT2):c.2560G>A (p.Asp854Asn)
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for KCNT2 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for KCNT2 Gene

Variant ID Type Subtype PubMed ID
esv1430984 CNV insertion 17803354
esv1933670 CNV deletion 18987734
esv2720973 CNV deletion 23290073
esv2720984 CNV deletion 23290073
esv2762213 CNV loss 21179565
esv3578348 CNV loss 25503493
esv3588460 CNV gain 21293372
esv3588462 CNV loss 21293372
esv3588464 CNV loss 21293372
esv3588465 CNV loss 21293372
nsv1112558 CNV deletion 24896259
nsv469680 CNV gain 16826518
nsv477253 CNV novel sequence insertion 20440878
nsv477628 CNV novel sequence insertion 20440878
nsv508685 CNV deletion 20534489
nsv528460 CNV gain 19592680
nsv548741 CNV loss 21841781
nsv548742 CNV loss 21841781
nsv832237 CNV gain 17160897

Variation tolerance for KCNT2 Gene

Residual Variation Intolerance Score: 1.81% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.70; 32.37% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for KCNT2 Gene

Human Gene Mutation Database (HGMD)
KCNT2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
KCNT2
Leiden Open Variation Database (LOVD)
KCNT2

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KCNT2 Gene

Disorders for KCNT2 Gene

MalaCards: The human disease database

(10) MalaCards diseases for KCNT2 Gene - From: OMI, CVR, GTR, SWI, COP, and GCD

- elite association - COSMIC cancer census association via MalaCards
Search KCNT2 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

KCNT2_HUMAN
  • Epileptic encephalopathy, early infantile, 57 (EIEE57) [MIM:617771]: A form of epileptic encephalopathy, a heterogeneous group of severe childhood onset epilepsies characterized by refractory seizures, neurodevelopmental impairment, and poor prognosis. Development is normal prior to seizure onset, after which cognitive and motor delays become apparent. EIEE57 is an autosomal dominant condition. {ECO:0000269 PubMed:29069600}. Note=The disease is caused by variants affecting the gene represented in this entry.

Additional Disease Information for KCNT2

genes like me logo Genes that share disorders with KCNT2: view

No data available for Genatlas for KCNT2 Gene

Publications for KCNT2 Gene

  1. Opposite regulation of Slick and Slack K+ channels by neuromodulators. (PMID: 16687497) Santi CM … Salkoff L (The Journal of neuroscience : the official journal of the Society for Neuroscience 2006) 3 4 22
  2. Slick (Slo2.1), a rapidly-gating sodium-activated potassium channel inhibited by ATP. (PMID: 14684870) Bhattacharjee A … Kaczmarek LK (The Journal of neuroscience : the official journal of the Society for Neuroscience 2003) 3 4 22
  3. A De Novo Mutation in the Sodium-Activated Potassium Channel KCNT2 Alters Ion Selectivity and Causes Epileptic Encephalopathy. (PMID: 29069600) Gururaj S … Bhattacharjee A (Cell reports 2017) 3 4
  4. International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels. (PMID: 16382103) Wei AD … Wulff H (Pharmacological reviews 2005) 2 3
  5. AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair. (PMID: 31900314) Chen Z … Chen J (Molecular & cellular proteomics : MCP 2020) 3

Products for KCNT2 Gene

Sources for KCNT2 Gene