Aliases for KCNK9 Gene
- Potassium Two Pore Domain Channel Subfamily K Member 9 2 3 5
- Potassium Channel, Two Pore Domain Subfamily K, Member 9 2 3
- Acid-Sensitive Potassium Channel Protein TASK-3 3 4
- TWIK-Related Acid-Sensitive K(+) Channel 3 3 4
- Potassium Channel Subfamily K Member 9 3 4
- Two Pore Potassium Channel KT3.2 3 4
External Ids for KCNK9 Gene
Previous GeneCards Identifiers for KCNK9 Gene
This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel dysmorphism syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
GeneCards Summary for KCNK9 Gene
KCNK9 (Potassium Two Pore Domain Channel Subfamily K Member 9) is a Protein Coding gene. Diseases associated with KCNK9 include Birk-Barel Syndrome and Kcnk9 Imprinting Syndrome. Among its related pathways are Activation of cAMP-Dependent PKA and Transmission across Chemical Synapses. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and potassium channel activity. An important paralog of this gene is KCNK3.
UniProtKB/Swiss-Prot Summary for KCNK9 Gene
pH-dependent, voltage-insensitive, background potassium channel protein.