Aliases for KCNK7 Gene
External Ids for KCNK7 Gene
Previous GeneCards Identifiers for KCNK7 Gene
This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for KCNK7 Gene
KCNK7 (Potassium Two Pore Domain Channel Subfamily K Member 7) is a Protein Coding gene. Diseases associated with KCNK7 include Adrenal Cortical Adenocarcinoma. Among its related pathways are Cardiac conduction and Neuropathic Pain-Signaling in Dorsal Horn Neurons. Gene Ontology (GO) annotations related to this gene include potassium channel activity and potassium ion leak channel activity. An important paralog of this gene is KCNK1.
UniProtKB/Swiss-Prot Summary for KCNK7 Gene
Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as yet unknown partner in order to reach the plasma membrane.