Aliases for KCNK16 Gene
External Ids for KCNK16 Gene
Previous GeneCards Identifiers for KCNK16 Gene
The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is expressed predominantly in the pancreas and is activated at alkaline pH. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008]
GeneCards Summary for KCNK16 Gene
KCNK16 (Potassium Two Pore Domain Channel Subfamily K Member 16) is a Protein Coding gene. Diseases associated with KCNK16 include Birk-Barel Syndrome and Maturity-Onset Diabetes Of The Young. Among its related pathways are Cardiac conduction and Sweet Taste Signaling. Gene Ontology (GO) annotations related to this gene include ion channel activity and voltage-gated ion channel activity. An important paralog of this gene is KCNK17.
UniProtKB/Swiss-Prot Summary for KCNK16 Gene
Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.