Aliases for KCNK13 Gene
External Ids for KCNK13 Gene
Previous GeneCards Identifiers for KCNK13 Gene
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a potassium channel containing two pore-forming domains. This protein is an open channel that can be stimulated by arachidonic acid and inhibited by the anesthetic halothane. [provided by RefSeq, Jul 2013]
GeneCards Summary for KCNK13 Gene
KCNK13 (Potassium Two Pore Domain Channel Subfamily K Member 13) is a Protein Coding gene. Diseases associated with KCNK13 include Birk-Barel Syndrome. Among its related pathways are Sweet Taste Signaling and Neuropathic Pain-Signaling in Dorsal Horn Neurons. Gene Ontology (GO) annotations related to this gene include potassium channel activity and potassium ion leak channel activity. An important paralog of this gene is KCNK12.
UniProtKB/Swiss-Prot Summary for KCNK13 Gene
Potassium channel displaying weak inward rectification in symmetrical K(+) solution.