Aliases for KCNK12 Gene
External Ids for KCNK12 Gene
Previous GeneCards Identifiers for KCNK12 Gene
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008]
GeneCards Summary for KCNK12 Gene
KCNK12 (Potassium Two Pore Domain Channel Subfamily K Member 12) is a Protein Coding gene. Diseases associated with KCNK12 include Lynch Syndrome I and Brain Glioblastoma Multiforme. Among its related pathways are Sweet Taste Signaling and Hepatic ABC Transporters. Gene Ontology (GO) annotations related to this gene include potassium channel activity and potassium ion leak channel activity. An important paralog of this gene is KCNK13.
UniProtKB/Swiss-Prot Summary for KCNK12 Gene
Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel (By similarity).