Aliases for KCNH7 Gene
External Ids for KCNH7 Gene
Previous GeneCards Identifiers for KCNH7 Gene
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. [provided by RefSeq, Jul 2008]
GeneCards Summary for KCNH7 Gene
KCNH7 (Potassium Voltage-Gated Channel Subfamily H Member 7) is a Protein Coding gene. Among its related pathways are Transmission across Chemical Synapses and Potassium Channels. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity and voltage-gated potassium channel activity. An important paralog of this gene is KCNH2.
UniProtKB/Swiss-Prot Summary for KCNH7 Gene
Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly.
Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The alpha-subunits contain a single pore-forming region and combine to form tetramers.