Aliases for KCNG2 Gene
External Ids for KCNG2 Gene
Previous GeneCards Identifiers for KCNG2 Gene
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit of the voltage-gated potassium channel. The delayed-rectifier type channels containing this subunit may contribute to cardiac action potential repolarization. [provided by RefSeq, Jul 2008]
GeneCards Summary for KCNG2 Gene
KCNG2 (Potassium Voltage-Gated Channel Modifier Subfamily G Member 2) is a Protein Coding gene. Among its related pathways are Metabolism and Dopamine-DARPP32 Feedback onto cAMP Pathway. Gene Ontology (GO) annotations related to this gene include ion channel activity and delayed rectifier potassium channel activity. An important paralog of this gene is KCNG1.
UniProtKB/Swiss-Prot Summary for KCNG2 Gene
Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.
Voltage-gated potassium channels (KV) belong to the 6-TM family of potassium channel that also comprises the Ca2+-activated Slo (actually 7-TM) and the Ca2+-activated SK subfamilies. The alpha-subunits contain a single pore-forming region and combine to form tetramers.