Aliases for KANSL3 Gene
Aliases for KANSL3 Gene
External Ids for KANSL3 Gene
- HGNC: 25473
- Entrez Gene: 55683
- Ensembl: ENSG00000114982
- OMIM: 617742
- UniProtKB: Q9P2N6
Previous HGNC Symbols for KANSL3 Gene
- KIAA1310
Previous GeneCards Identifiers for KANSL3 Gene
- GC02M097259
Summaries for KANSL3 Gene
GeneCards Summary for KANSL3 Gene
KANSL3 (KAT8 Regulatory NSL Complex Subunit 3) is a Protein Coding gene. Diseases associated with KANSL3 include Colorblindness, Partial, Protan Series and Calcific Tendinitis. Among its related pathways are Chromatin organization. Gene Ontology (GO) annotations related to this gene include histone acetyltransferase activity (H4-K5 specific) and histone acetyltransferase activity (H4-K16 specific).
UniProtKB/Swiss-Prot for KANSL3 Gene
-
As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
Additional gene information for KANSL3 Gene
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KANSL3 Gene
Genomics for KANSL3 Gene
GeneHancer (GH) Regulatory Elements for KANSL3 Gene
Promoters and enhancers for KANSL3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around KANSL3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for KANSL3 Gene
Genomic Locations for KANSL3 Gene
- chr2:96,593,155-96,642,787
- (GRCh38/hg38)
- Size:
- 49,633 bases
- Orientation:
- Minus strand
- chr2:97,258,907-97,308,524
- (GRCh37/hg19)
- Size:
- 49,618 bases
- Orientation:
- Minus strand
Genomic View for KANSL3 Gene
Genes around KANSL3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q11.2 by Entrez Gene
- 2q11.2 by HGNC
- 2q11.2 by Ensembl
KANSL3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for KANSL3 Gene
Proteins for KANSL3 Gene
-
Protein details for KANSL3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9P2N6-KANL3_HUMAN
- Recommended name:
- KAT8 regulatory NSL complex subunit 3
- Protein Accession:
- Q9P2N6
- A1L184
- D3DXH3
- D3DXH4
- Q05BU4
- Q6P3X2
- Q6PJH6
- Q86T19
- Q96L64
- Q9H0C9
- Q9H8C9
- Q9HAP8
- Q9NWE5
Protein attributes for KANSL3 Gene
- Size:
- 904 amino acids
- Molecular mass:
- 95992 Da
- Quaternary structure:
-
- Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
- SequenceCaution:
-
- Sequence=AAH15469.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=AAI27821.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the C-terminal part.; Evidence={ECO:0000305}; Sequence=BAA92548.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for KANSL3 Gene
Post-translational modifications for KANSL3 Gene
Other Protein References for KANSL3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- XP_011509760.1
- XP_011509763.1
- NP_001108488.1
- XP_011509765.1
- XP_005264044.1
- XP_011509762.1
- XP_016859961.1
- NP_001336188.1
- XP_011509764.1
- NP_001336185.1
- XP_011509757.1
- XP_011509769.1
- XP_011509759.1
- NP_001336186.1
- NP_001336190.1
- NP_001336189.1
- XP_011509766.1
- XP_011509756.1
- XP_011509768.1
- XP_011509758.1
- NP_001336187.1
- XP_011509761.1
- NP_001336191.1
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for KANSL3
- Novus Biologicals Antibodies for KANSL3
- Invitrogen Antibodies for KANSL3 (AFLGC-KANSL3)
- GeneTex KANSL3 Antibody for KANSL3
Protein Products
-
OriGene Purified Proteins for KANSL3
- Search Origene for MassSpec and Protein Over-expression Lysates for KANSL3
- Origene Custom Protein Services for KANSL3
- antibodies-online: Search results for 3 available KANSL3 Proteins ranked by validation data
- Compare Top KANSL3 Proteins
-
Quality Products:
- Search GeneTex for Proteins for KANSL3
Assay Products
No data available for DME Specific Peptides for KANSL3 Gene
Domains & Families for KANSL3 Gene
Gene Families for KANSL3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for KANSL3 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for KANSL3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for KANSL3 Gene
Function for KANSL3 Gene
Molecular function for KANSL3 Gene
- UniProtKB/Swiss-Prot Function:
- As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
Phenotypes From GWAS Catalog for KANSL3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004402 | CONTRIBUTES_TO histone acetyltransferase activity | IBA | -- |
| GO:0043995 | contributes_to histone acetyltransferase activity (H4-K5 specific) | IDA | 20018852 |
| GO:0043996 | contributes_to histone acetyltransferase activity (H4-K8 specific) | IDA | 20018852 |
| GO:0046972 | contributes_to histone acetyltransferase activity (H4-K16 specific) | IDA | 20018852 |
Phenotypes for KANSL3 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for KANSL3
-
CRISPR Products
-
OriGene CRISPR knockouts for KANSL3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for KANSL3
- genomics-online: gRNA clones - Search results for 82 available KANSL3 gene related products
- Overview of 82 available KANSL3 gene related products
- Applied Biological Materials CRISPR for KANSL3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for KANSL3
- GenScript: Design CRISPR guide RNA sequences for KANSL3
miRNA for KANSL3 Gene
- miRTarBase miRNAs that target KANSL3
-
- hsa-mir-26b-5p (MIRT030314)
- hsa-mir-877-3p (MIRT036963)
- hsa-mir-93-3p (MIRT038818)
- hsa-mir-484 (MIRT041753)
- hsa-mir-92a-3p (MIRT049440)
- hsa-mir-16-5p (MIRT051184)
- hsa-mir-3156-3p (MIRT643607)
- hsa-mir-1260b (MIRT643608)
- hsa-mir-1260a (MIRT643609)
- hsa-mir-188-3p (MIRT643610)
- hsa-mir-4301 (MIRT643611)
- hsa-mir-4705 (MIRT643612)
- hsa-mir-6500-3p (MIRT643613)
- hsa-mir-141-5p (MIRT643614)
- hsa-mir-196a-3p (MIRT712971)
- hsa-mir-7106-3p (MIRT712972)
- hsa-mir-3128 (MIRT712973)
- hsa-mir-150-5p (MIRT712974)
- hsa-mir-8073 (MIRT712975)
- hsa-mir-221-5p (MIRT712976)
- hsa-mir-1273g-3p (MIRT712977)
- hsa-mir-21-5p (MIRT763857)
- hsa-mir-3200-5p (MIRT765515)
- hsa-mir-4539 (MIRT770232)
- hsa-mir-4754 (MIRT771942)
- hsa-mir-590-5p (MIRT775360)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for KANSL3
- Browse OriGene Inhibitory RNA Products For KANSL3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KANSL3
- genomics-online: shRNA clones - Search results for 82 available KANSL3 gene related products
- Overview of 82 available KANSL3 gene related products
Clone Products
-
GenScript: Next-day shipping of latest version cDNA ORF clones for KANSL3 in any vector
- XM_011511463.2
- NM_001115016.2
- XM_011511460.2
- XM_011511464.2
- XM_011511466.2
- XM_011511455.2
- XM_005263982.2
- XM_011511462.2
- XM_011511457.2
- XM_011511459.2
- XM_011511467.2
- XM_011511454.2
- XM_011511456.2
- XM_011511461.2
- XM_011511458.2
- NM_001349262.1
- NM_001349261.1
- XM_017004472.1
- NM_001349258.1
- NM_001349256.1
- XM_005263984.1
- XM_017004473.1
- XM_017004474.1
- NM_001349259.1
- NM_001349257.1
- NM_001349260.1
- XM_005263987.1
- XM_017004471.1
- XM_017004470.1
- Sino Biological Human cDNA Clone for KANSL3
- Addgene plasmids for KANSL3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for KANSL3
- Applied Biological Materials Clones for KANSL3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KANSL3 Gene
Localization for KANSL3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for KANSL3 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
| extracellular | 1 |
| mitochondrion | 1 |
- Nucleus (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000123 | histone acetyltransferase complex | IDA | 20018852 |
| GO:0005634 | nucleus | IDA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005730 | nucleolus | IDA | -- |
| GO:0043231 | intracellular membrane-bounded organelle | IDA | -- |
Pathways & Interactions for KANSL3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Chromatin organization | ||
Pathways by source for KANSL3 Gene
3 Reactome pathways for KANSL3 Gene
Interacting Proteins for KANSL3 Gene
GPS-Prot Interaction Network for KANSL3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006325 | chromatin organization | IEA | -- |
| GO:0016573 | histone acetylation | IBA | -- |
| GO:0043981 | histone H4-K5 acetylation | IDA | 20018852 |
| GO:0043982 | histone H4-K8 acetylation | IDA | 20018852 |
| GO:0043984 | histone H4-K16 acetylation | IDA | 20018852 |
No data available for SIGNOR curated interactions for KANSL3 Gene
Drugs & Compounds for KANSL3 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Naringenin | Experimental | Pharma | Target | 2 |
Drug Products
Transcripts for KANSL3 Gene
mRNA/cDNA for KANSL3 Gene
- (24) REFSEQ mRNAs :
- (23) Additional mRNA sequences :
- (402) Selected AceView cDNA sequences:
- (20) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000354204 5253 bps (uc061lwa.1)
- ENST00000447759 5012 bps (uc061lwb.1)
- ENST00000487070 4937 bps (uc002swj.6)
- ENST00000431828 5153 bps (uc002swn.6)
- ENST00000420155 5028 bps (uc061lwc.1)
Unigene Clusters for KANSL3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for KANSL3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for KANSL3
- genomics-online: gRNA clones - Search results for 82 available KANSL3 gene related products
- Overview of 82 available KANSL3 gene related products
- Applied Biological Materials CRISPR for KANSL3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for KANSL3
- GenScript: Design CRISPR guide RNA sequences for KANSL3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for KANSL3
- Browse OriGene Inhibitory RNA Products For KANSL3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KANSL3
- genomics-online: shRNA clones - Search results for 82 available KANSL3 gene related products
- Overview of 82 available KANSL3 gene related products
Clone Products
-
GenScript: Next-day shipping of latest version cDNA ORF clones for KANSL3 in any vector
- XM_011511463.2
- NM_001115016.2
- XM_011511460.2
- XM_011511464.2
- XM_011511466.2
- XM_011511455.2
- XM_005263982.2
- XM_011511462.2
- XM_011511457.2
- XM_011511459.2
- XM_011511467.2
- XM_011511454.2
- XM_011511456.2
- XM_011511461.2
- XM_011511458.2
- NM_001349262.1
- NM_001349261.1
- XM_017004472.1
- NM_001349258.1
- NM_001349256.1
- XM_005263984.1
- XM_017004473.1
- XM_017004474.1
- NM_001349259.1
- NM_001349257.1
- NM_001349260.1
- XM_005263987.1
- XM_017004471.1
- XM_017004470.1
- Sino Biological Human cDNA Clone for KANSL3
- Addgene plasmids for KANSL3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for KANSL3
- Applied Biological Materials Clones for KANSL3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP12: | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP14: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP15: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP16: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP17: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP18: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP19: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP20: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP21: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP22: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP23: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP24: |
| ExUns: | 11c | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | ^ | 22a | · | 22b | ^ | 23a | · | 23b | ^ | 24 | ^ | 25a | · | 25b | ^ | 26a | · | 26b | ^ | 27 | ^ | 28 | ^ | 29a | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP17: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP18: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP19: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP20: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP21: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP22: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP23: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP24: |
Expression for KANSL3 Gene
This gene is overexpressed in Liver, secretome (27.6), Peripheral blood mononuclear cells (19.3), and CD8 Tcells (9.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for KANSL3 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of KANSL3 Gene:
KANSL3SOURCE GeneReport for Unigene cluster for KANSL3 Gene:
Hs.516341Evidence on tissue expression from TISSUES for KANSL3 Gene
- Nervous system(4.8)
- Intestine(4.3)
- Lung(3.6)
Primer Products
-
OriGene qPCR primer pairs for KANSL3
- genomics-online: primer clones - Search results for 82 available KANSL3 gene related products
- Overview of 82 available KANSL3 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KANSL3 Gene
Orthologs for KANSL3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | KANSL3 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | KANSL3 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | KANSL3 34 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Kansl3 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Kansl3 16 34 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | KANSL3 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| -- 34 |
|
OneToMany | |||
| chicken (Gallus gallus) |
Aves | KANSL3 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | KANSL3 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC100158552 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | kansl3 34 33 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | Rcd1 34 |
|
OneToOne | |
| worm (Caenorhabditis elegans) |
Secernentea | F54D11.2 34 |
|
OneToOne | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne |
- Species where no ortholog for KANSL3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for KANSL3 Gene
- ENSEMBL:
- Gene Tree for KANSL3 (if available)
- TreeFam:
- Gene Tree for KANSL3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for KANSL3: view image
Paralogs for KANSL3 Gene
No data available for Paralogs for KANSL3 Gene
Variants for KANSL3 Gene
| SNP ID | Clin | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000045868 | -- | 96,614,185(-) | G/A | intron_variant | |
| rs1000252655 | -- | 96,634,707(-) | T/A | intron_variant | |
| rs1000254129 | -- | 96,593,136(-) | G/T | downstream_transcript_variant | |
| rs1000287855 | -- | 96,612,750(-) | TTCTTCT/TTCT | intron_variant | |
| rs1000376637 | -- | 96,620,309(-) | C/T | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv607e201 | CNV | deletion | 23290073 |
| esv2660856 | CNV | deletion | 23128226 |
| esv2720413 | CNV | deletion | 23290073 |
| esv3425717 | CNV | duplication | 20981092 |
| esv5003 | OTHER | complex | 18987735 |
| nsv1135873 | CNV | deletion | 24896259 |
| nsv1138819 | CNV | deletion | 24896259 |
| nsv469775 | CNV | loss | 16826518 |
| nsv819818 | CNV | loss | 19587683 |
| nsv834306 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
27.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.17;
61.69% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for KANSL3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- KANSL3
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KANSL3 Gene
Disorders for KANSL3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| colorblindness, partial, protan series |
|
|
| calcific tendinitis |
|
|
Search KANSL3 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for KANSL3
No data available for UniProtKB/Swiss-Prot and Genatlas for KANSL3 Gene
Publications for KANSL3 Gene
- Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex. (PMID: 20018852) Cai Y … Conaway RC (The Journal of biological chemistry 2010) 3 4 58
- Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila. (PMID: 16543150) Mendjan S … Akhtar A (Molecular cell 2006) 3 4 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S … Poustka A (Genome research 2001) 3 4 58
- Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2000) 3 4 58
Products for KANSL3 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for KANSL3
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for KANSL3
- Search Origene for MassSpec and Protein Over-expression Lysates for KANSL3
- Origene Custom Protein Services for KANSL3
- Origene shrna, sirna, and RNAi products in human, mouse, rat for KANSL3
- Browse OriGene Inhibitory RNA Products For KANSL3
- OriGene qPCR primer pairs for KANSL3
- OriGene CRISPR knockouts for KANSL3
- OriGene ORF clones in human for KANSL3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For KANSL3
- GenScript: Next-day shipping of latest version cDNA ORF clones for KANSL3 in any vector
- XM_011511463.2
- NM_001115016.2
- XM_011511460.2
- XM_011511464.2
- XM_011511466.2
- XM_011511455.2
- XM_005263982.2
- XM_011511462.2
- XM_011511457.2
- XM_011511459.2
- XM_011511467.2
- XM_011511454.2
- XM_011511456.2
- XM_011511461.2
- XM_011511458.2
- NM_001349262.1
- NM_001349261.1
- XM_017004472.1
- NM_001349258.1
- NM_001349256.1
- XM_005263984.1
- XM_017004473.1
- XM_017004474.1
- NM_001349259.1
- NM_001349257.1
- NM_001349260.1
- XM_005263987.1
- XM_017004471.1
- XM_017004470.1
- GenScript Custom Purified and Recombinant Proteins Services for KANSL3
- GenScript Custom Assay Services for KANSL3
- GenScript Custom overexpressing Cell Line Services for KANSL3
- GenScript: Design CRISPR guide RNA sequences for KANSL3
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for KANSL3
- Sino Biological Human cDNA Clone for KANSL3
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for KANSL3
- Novus Biologicals lysates and proteins for KANSL3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for KANSL3 (AFLGC-KANSL3)
- Cyagen custom Knockout/knockin (KOKI) mouse models for KANSL3
- Addgene plasmids for KANSL3
- antibodies-online: Search results for 27 available KANSL3 Antibodies ranked by validation data
- Compare Top KANSL3 Antibodies
- antibodies-online: Search results for available KANSL3 related products ranked by validation data
- antibodies-online: Search results for 3 available KANSL3 Proteins ranked by validation data
- Compare Top KANSL3 Proteins
- Quality Products:
- GeneTex KANSL3 Antibody for KANSL3
- Search GeneTex for Proteins for KANSL3
- genomics-online: cdna clones - Search results for 82 available KANSL3 gene related products
- Overview of 82 available KANSL3 gene related products
- orf clones - Search results for 82 available KANSL3 gene related products
- Overview of 82 available KANSL3 gene related products
- genomics-online: gRNA clones - Search results for 82 available KANSL3 gene related products
- Overview of 82 available KANSL3 gene related products
- genomics-online: primer clones - Search results for 82 available KANSL3 gene related products
- Overview of 82 available KANSL3 gene related products
- genomics-online: shRNA clones - Search results for 82 available KANSL3 gene related products
- Overview of 82 available KANSL3 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for KANSL3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for KANSL3
- GeneCopoeia miRNA 3'UTR Target clone products for KANSL3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for KANSL3
Sources for KANSL3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt