Aliases for JPT2 Gene

Aliases for JPT2 Gene

  • Jupiter Microtubule Associated Homolog 2 2 3 3 4 5
  • Hematological And Neurological Expressed 1-Like Protein 3 4
  • Hematological And Neurological Expressed 1 Like 2 3
  • HN1-Like Protein 3 4
  • C16orf34 3 4
  • HN1L 3 4
  • Hematological And Neurological Expressed 1-Like 2
  • Chromosome 16 Open Reading Frame 34 2
  • CRAMP_1 Like 3
  • HN1 Like 3
  • L11 3

External Ids for JPT2 Gene

Previous HGNC Symbols for JPT2 Gene

  • C16orf34
  • HN1L

Summaries for JPT2 Gene

GeneCards Summary for JPT2 Gene

JPT2 (Jupiter Microtubule Associated Homolog 2) is a Protein Coding gene.

Gene Wiki entry for JPT2 Gene

Additional gene information for JPT2 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for JPT2 Gene

Genomics for JPT2 Gene

GeneHancer (GH) Regulatory Elements for JPT2 Gene

Promoters and enhancers for JPT2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around JPT2 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for JPT2

Genomic Locations for JPT2 Gene

Genomic Locations for JPT2 Gene
24,025 bases
Plus strand
24,025 bases
Plus strand

Genomic View for JPT2 Gene

Genes around JPT2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
JPT2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for JPT2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for JPT2 Gene

Proteins for JPT2 Gene

  • Protein details for JPT2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Jupiter microtubule associated homolog 2
    Protein Accession:
    Secondary Accessions:
    • B1AJY2
    • B4DLH4
    • Q6EIC7

    Protein attributes for JPT2 Gene

    190 amino acids
    Molecular mass:
    20063 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for JPT2 Gene


neXtProt entry for JPT2 Gene

Post-translational modifications for JPT2 Gene

  • Glycosylation at Thr159
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for JPT2 Gene

Domains & Families for JPT2 Gene

Gene Families for JPT2 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for JPT2 Gene


Suggested Antigen Peptide Sequences for JPT2 Gene

GenScript: Design optimal peptide antigens:
  • cDNA, FLJ79413, highly similar to Hematological and neurological expressed 1-like protein (A6NGP5_HUMAN)
  • cDNA FLJ60660, highly similar to Hematological and neurological expressed1-like protein (B4DL85_HUMAN)
  • cDNA FLJ53622, highly similar to Hematological and neurological expressed1-like protein (B4DLH4_HUMAN)
  • Hematological and neurological expressed 1-like protein (HN1L_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the JUPITER family.
  • Belongs to the JUPITER family.
genes like me logo Genes that share domains with JPT2: view

Function for JPT2 Gene

Molecular function for JPT2 Gene

UniProtKB/Swiss-Prot Induction:
Up-regulated in squamous cell carcinoma (SCC) adenocarcinoma (AC), adenosquamous cell carcinoma (ASCC), bronchioalveolar carcinoma (BAC), breast and uterus tumors.

Phenotypes From GWAS Catalog for JPT2 Gene

Phenotypes for JPT2 Gene

genes like me logo Genes that share phenotypes with JPT2: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for JPT2 Gene

Localization for JPT2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for JPT2 Gene

Cytoplasm. Nucleus.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for JPT2 gene
Compartment Confidence
plasma membrane 5
cytosol 5
nucleus 4

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (4)
  • Plasma membrane (4)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for JPT2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol IDA --
GO:0005886 plasma membrane IDA --
genes like me logo Genes that share ontologies with JPT2: view

Pathways & Interactions for JPT2 Gene

PathCards logo

SuperPathways for JPT2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for JPT2 Gene


No data available for Pathways by source and SIGNOR curated interactions for JPT2 Gene

Drugs & Compounds for JPT2 Gene

No Compound Related Data Available

Transcripts for JPT2 Gene

mRNA/cDNA for JPT2 Gene

15 NCBI additional mRNA sequence :
14 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for JPT2 Gene

No ASD Table

Relevant External Links for JPT2 Gene

GeneLoc Exon Structure for

Expression for JPT2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for JPT2

mRNA Expression by UniProt/SwissProt for JPT2 Gene:

Tissue specificity: Expressed in liver, kidney, prostate, testis and uterus.

Evidence on tissue expression from TISSUES for JPT2 Gene

  • Nervous system(4.8)
  • Liver(4.2)
  • Skin(4.2)
genes like me logo Genes that share expression patterns with JPT2: view

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for JPT2 Gene

Orthologs for JPT2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for JPT2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia HN1L 31 30
  • 99.65 (n)
(Canis familiaris)
Mammalia HN1L 31 30
  • 82.62 (n)
(Mus musculus)
Mammalia Hn1l 31 30
  • 80.88 (n)
Jpt2 17
(Rattus norvegicus)
Mammalia Hn1l 30
  • 80.7 (n)
(Bos Taurus)
Mammalia HN1L 31 30
  • 78.57 (n)
(Ornithorhynchus anatinus)
Mammalia HN1L 31
  • 65 (a)
(Monodelphis domestica)
Mammalia -- 31
  • 65 (a)
-- 31
  • 64 (a)
(Gallus gallus)
Aves HN1L 31 30
  • 67.55 (n)
(Anolis carolinensis)
Reptilia HN1L 31
  • 53 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia hn1l 30
  • 57.58 (n)
(Danio rerio)
Actinopterygii hn1l 31 30
  • 54.72 (n)
wufb37f03 30
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.297 30
Species where no ortholog for JPT2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for JPT2 Gene

Gene Tree for JPT2 (if available)
Gene Tree for JPT2 (if available)
Evolutionary constrained regions (ECRs) for JPT2: view image

Paralogs for JPT2 Gene

No data available for Paralogs for JPT2 Gene

Variants for JPT2 Gene

Additional dbSNP identifiers (rs#s) for JPT2 Gene

Structural Variations from Database of Genomic Variants (DGV) for JPT2 Gene

Variant ID Type Subtype PubMed ID
dgv4855n54 CNV loss 21841781
dgv4856n54 CNV loss 21841781
esv2422427 CNV duplication 17116639
nsv1051692 CNV loss 25217958
nsv428317 CNV gain 18775914
nsv478955 CNV novel sequence insertion 20440878
nsv518641 CNV loss 19592680
nsv833118 CNV loss 17160897

Variation tolerance for JPT2 Gene

Residual Variation Intolerance Score: 50.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.32; 7.16% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for JPT2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for JPT2 Gene

Disorders for JPT2 Gene

Additional Disease Information for JPT2

No disorders were found for JPT2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for JPT2 Gene

Publications for JPT2 Gene

  1. Cloning, expression and subcellular localization of HN1 and HN1L genes, as well as characterization of their orthologs, defining an evolutionarily conserved gene family. (PMID: 15094197) Zhou G … Zhao S (Gene 2004) 2 3 4 23 54
  2. Jupiter, a new Drosophila protein associated with microtubules. (PMID: 16518797) Karpova N … Debec A (Cell motility and the cytoskeleton 2006) 2 3 54
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54
  5. Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer. (PMID: 15334068) Petroziello J … Carter P (Oncogene 2004) 3 4 54

Products for JPT2 Gene

Sources for JPT2 Gene